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Showing 1–24 of 117 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers

NCT01779024
Conditions
fMRI, Alcohol Drinking, Alcoholism
Interventions
Ghrelin, Placebo, fMRI, Alcohol
Drug · Procedure
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Heavy Drinking
Interventions
Academic Episodic Future Thinking, Vivid Memory Task
Behavioral · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 25 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Alcoholism
Interventions
Perampanel, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
Farmington, Connecticut • New Haven, Connecticut • West Haven, Connecticut + 1 more
Conditions
Alcoholism
Interventions
Prazosin medication, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Use Disorder (AUD)
Interventions
Stand Down mobile app, Standard Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
15
States / cities
Phoenix, Arizona • Fayetteville, Arkansas • Washington D.C., District of Columbia + 12 more
Not yet recruiting Phase 2 Interventional

Effects of Nimodipine on Alcohol Drinking

NCT07681869
Conditions
Alcohol Use Disorder
Interventions
Nimodipine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects

NCT00329407
Conditions
Alcoholism
Interventions
Topiramate (Topamax)
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 4 Interventional Results available

Alcohol Disorder hOsPital Treatment Trial

NCT02478489
Conditions
Heavy Drinking, Alcohol Dependence, Alcohol Use Disorder
Interventions
Oral naltrexone (PO-NTX), Extended-release injectable naltrexone (XR-NTX)
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Brief Online Intervention for Veterans

NCT04244461
Conditions
Heavy Drinking, Mental Health Wellness
Interventions
Personalized Normative Feedback
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 40 Years
Enrollment
754 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Terminated Phase 2 Interventional Results available

Topiramate's Effects on Heavy Drinking

NCT02074904
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol and Sex Risk Intervention for MSM Supplement

NCT03522948
Conditions
Heavy Drinking and Sexual Risk Behavior
Interventions
Brief intervention with text messaging to reduce sexual risk and heavy drinking among MSM
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sexual Aggression, Heavy Drinking
Interventions
Cognitive Restructuring, Mindfulness, Alcohol consumption
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 30 Years · Male only
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Consumption
Interventions
Sham iTBS, Active iTBS, 10 Hz TMS, 1 Hz TMS
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation

NCT02859142
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Chantix, Behavioral Counseling Sessions, NicodermCQ, Placebo
Drug · Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 85 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Smoking Tobacco and Drinking Study

NCT03163303
Conditions
Smoking, Heavy Episodic Drinking
Interventions
Tobacco Status Project Intervention, Tobacco Status Project + Alcohol Intervention, nicotine patch
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 25 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Regular Heavy AOD Use, Excessive Drinking
Interventions
Treatment Group
Behavioral
Lead sponsor
Pro-Change Behavior Systems
Other
Eligibility
21 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
South Kingstown, Rhode Island
Conditions
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Interventions
Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Full Motivational Interviewing ("FMI"), Spirit Only Motivational Interviewing ("SOMI")
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 65 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Probiotics, Immune Function, and the Brain in Alcohol Consumers

NCT05232682
Conditions
Alcohol; Use, Problem
Interventions
Seed DS-01 Daily Synbiotic
Dietary Supplement
Lead sponsor
Brown University
Other
Eligibility
18 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers

Brief Web-Based Alcohol Reduction Intervention for Undergraduates

NCT01694082
Conditions
Alcohol Use, Heavy Drinking, Negative Consequences of Alcohol Use
Interventions
THRIVE, Brief brochure and assessment control
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Alcohol Dependence, Alcohol Abuse/Dependence, Alcohol Addiction
Interventions
Deep TMS (DTMS), Sham (No Treatment)
Device
Lead sponsor
Brainsway
Industry
Eligibility
18 Years to 86 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
Tuscaloosa, Alabama • La Jolla, California • West Palm Beach, Florida + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multimodal Sleep Intervention Using Wearable Technology

NCT03658954
Conditions
Drinking, Alcohol
Interventions
Advice, Self-monitoring, Feedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing

NCT03435783
Conditions
HIV Infections, Alcohol Abuse
Interventions
Brief Electronic Intervention, Attention-Matched Control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Sexual Assault, Heavy Drinking
Interventions
Alc-ERDT
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Seattle, Washington