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Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Driving Impaired Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
View directory record Official record
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations

NCT04856566
View directory record Official record
Conditions
Marijuana Impairment, Alcohol Impairment
Interventions
Low Marijuana, Hash, THC, or Grass, High Marijuana, Hash, THC, or Grass, Placebo, 0.05 BAC Alcohol, 0.08 BAC Alcohol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validation of Alcohol Level Identification Using DRIVESC

NCT07282405
View directory record Official record
Conditions
Driving Impaired
Interventions
DRIVESC, Alcohol
Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050
View directory record Official record
Conditions
Drinking and Driving
Interventions
BAC feedback/warning, No BAC feedback/warning
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 35 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Driving Simulation to Assess Non-Sedative Effects of Tolperisone

NCT03353922
View directory record Official record
Conditions
Driving Impaired
Interventions
Cyclobenzaprine 10 Mg Oral Tablet, Placebo Oral Tablet
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Long Beach, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High Confusion: Cannabis & Driving

NCT06236815
View directory record Official record
Conditions
Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
Interventions
Delta-9-THC, Delta-8-THC, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 49 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional

Speed of Processing Training in Adults With HIV

NCT02758093
View directory record Official record
Conditions
HIV, Cognition - Other, Impaired Driving
Interventions
Speed of Processing Training, Internet Navigational
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 6, 2021 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fire Fighter Fatigue Management Program: Operation Fight Fatigue

NCT01672502
View directory record Official record
Conditions
Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea, Impaired Driving
Interventions
Sleep health education provided via a web-based program, Sleep disorder detection and treatment, Optimization of Sleep in Fire Station
Behavioral · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving

NCT05469477
View directory record Official record
Conditions
Distracted Driving, Impaired Driving, Driving Behaviors
Interventions
Persuasive education, WOOP (aka, mental contrasting with implementation intentions., Wish, Outcome, Obstacle, Plan), Customized Habit Tips, Raffle Financial Incentive, Shared Pot Financial Incentive, Weekly SMS Support text, Weekly SMS Encouragement
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants

NCT03638596
View directory record Official record
Conditions
Drunk Driving
Interventions
Contingency Management, Control
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fire Fighter Fatigue Management Program: Operation Healthy Sleep

NCT01988129
View directory record Official record
Conditions
Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea, Impaired Driving, Injuries
Interventions
Sleep disorders education and screening
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

NCT04587609
View directory record Official record
Conditions
Distracted Driving, Driving Impaired
Interventions
Free Phone Mounts, Commitment Contract, Personalized Habit Tips, Social Gamification Feedback, "Contest" Financial Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,668 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Phase 4 Interventional Results available

Vivitrol for Reducing Driving While Impaired Behavior Among Repeat Offenders

NCT00537745
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Vivitrol (Medication Therapy), Medication Management Therapy
Drug · Other
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 26, 2012 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sedative-Anxiolytic Effects on Simulated Driving Performance

NCT03297944
View directory record Official record
Conditions
Psychomotor Impairment
Interventions
Alprazolam 2mg (2ALP/PLC), Alprazolam 1mg (1ALP/PLC), Alprazolam 0.5mg (0.5ALP/PLC), Zolpidem 10mg (ZOL/PLC), Placebo (PLC/PLC), Alprazolam 1mg (PLC/ALC)
Drug
Lead sponsor
Marion Coe
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Jul 21, 2026, 10:24 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents

NCT04564599
View directory record Official record
Conditions
Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use, Motor Collision, Sexual Assault
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 10:24 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Cannabis Consumption and Driving Impairment Assessment on a Closed Course

NCT06059677
View directory record Official record
Conditions
Cannabis Smoking, Driving Impaired
Interventions
Active smoked cannabis, Placebo smoked cannabis
Drug
Lead sponsor
Bayliss J. Camp, PhD
Government
Eligibility
21 Years to 55 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Standardized Field Test for Marijuana Impairment II

NCT05115513
View directory record Official record
Conditions
Marijuana Impairment
Interventions
Medium THC, Placebo THC
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Impaired Driving in the Natural Environment

NCT03503396
View directory record Official record
Conditions
Driving Under the Influence
Interventions
BAC Driving Feedback/Warning, No Feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 21, 2026, 10:24 PM EDT
Completed Phase 4 Interventional Results available

Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease

NCT00476008
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Memantine, Placebo
Drug
Lead sponsor
Florida Atlantic University
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Jul 21, 2026, 10:24 PM EDT