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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277
View directory record Official record
Conditions
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil, Alcohol Effect, Driving Under the Influence, Alcohol Impairment
Interventions
Active Ethanol, Active Iomazenil, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 35 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jul 21, 2026, 4:41 PM EDT
Terminated Not applicable Interventional

Study of Acamprosate in Driving Under the Influence (DUI) Court Participants

NCT00425711
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Acamprosate
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 64 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Behavior and Driving Safety Study

NCT00575679
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Brief motivational interview
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Jul 21, 2026, 4:41 PM EDT
Completed No phase listed Observational

Effect of Interferon Beta-1a (Avonex®) on Changes of Non-conventional MRI Measures in Patients With MS

NCT00463710
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Avonex® monotherapy (6.0 MIU administered i.m. each week)
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2020 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting No phase listed Observational

Community-based Partnership's Efficacy in Decreasing Injury Rates At Night in Dallas, TX

NCT06695416
View directory record Official record
Conditions
Blood Alcohol Concentration, Drunk Driving
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Phase 2 Interventional

Evaluation of an School-based Alcohol Prevention Program for Middle School Students

NCT01847183
View directory record Official record
Conditions
Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
Interventions
Click City®: Alcohol
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
12 Years to 16 Years
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 21, 2026, 4:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional

A Web Application to Reduce Heavy Drinking in First-time DWI Offenders

NCT02071836
View directory record Official record
Conditions
Driving While Intoxicated, Driving Under the Influence, Heavy Drinking, Alcohol Abstinence
Interventions
Right Turns web application, Treatment as usual
Behavioral
Lead sponsor
Behavior Therapy Associates, LLP
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jul 21, 2026, 4:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

WayToServePlus: Improving Responsible Alcohol Service Ph II

NCT05779774
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Use, Unspecified
Interventions
WayToServe Plus In-service Component, WayToServe Training Only
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
19 Years and older
Enrollment
1,172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

NCT02709954
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active inhaled delta-9-THC, Placebo, Active Oral Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

NCT05276232
View directory record Official record
Conditions
Cannabis
Interventions
Cannabis(THC) inhaled
Drug
Lead sponsor
ISBRG Corp
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving

NCT03335735
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive, Driving Impaired, Driving Under the Influence, Behavior, Drinking
Interventions
Loss-framed text message, Gain-Framed text message
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Global Smart Drinking Goals Initiative

NCT03262259
View directory record Official record
Conditions
Binge Drinking, Underage Drinking, Drinking and Driving, Alcohol-Related Harms
Interventions
GSDG multi-component intervention
Behavioral
Lead sponsor
HBSA
Other
Eligibility
12 Years and older
Enrollment
36,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Calverton, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim

NCT04970342
View directory record Official record
Conditions
Driving Behavior, Driving Under the Influence
Interventions
Placebo (Lactose) Capsule, 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
Drug
Lead sponsor
Timothy L. Brown
Other
Eligibility
19 Years to 45 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Jul 21, 2026, 4:41 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

NCT02404688
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active delta-9-THC, Placebo, Active Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking

NCT02849587
View directory record Official record
Conditions
Cannabis Intoxication
Interventions
Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Perceived Fitness to Drive While Intoxicated

NCT05028413
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Perception, Self, Drinking, Alcohol, Driving Under the Influence, Drinking Behavior
Interventions
Participants Shown their Breath Alcohol Content Measurement
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
View directory record Official record
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validation of Alcohol Level Identification Using DRIVESC

NCT07282405
View directory record Official record
Conditions
Driving Impaired
Interventions
DRIVESC, Alcohol
Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050
View directory record Official record
Conditions
Drinking and Driving
Interventions
BAC feedback/warning, No BAC feedback/warning
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 35 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jul 21, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

WayToServePlus: Improving Responsible Alcohol Service Ph I

NCT05146024
View directory record Official record
Conditions
Driving While Intoxicated
Interventions
Way To Serve Plus: Improving Responsible Alcohol Service
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
19 Years and older
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Berkeley, California • Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 11, 2023 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Behavior and Driving Safety Study II

NCT01270217
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Brief motivational interview
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Jul 21, 2026, 4:41 PM EDT