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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:14 AM EDT

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Showing 433–456 of 460 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Drug Abuse Clear all
Completed No phase listed Observational Results available

Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study

NCT00653263
View directory record Official record
Conditions
Methamphetamine Dependence, Methamphetamine Withdrawal
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse

NCT02080819
View directory record Official record
Conditions
Cocaine Dependence
Interventions
levodopa/carbidopa 400/100 BID
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Expectancy Challenges to Prevent Nonmedical Prescription Stimulant Use

NCT03648684
View directory record Official record
Conditions
Prescription Drug Abuse (Not Dependent)
Interventions
Caffeine-Based Expectancy Challenge, Placebo-Based Expectancy Challenge
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 25 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 21, 2026, 10:14 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Clinical Time and Temporal Dynamics Study (CLIN-TIME)

NCT07812831
View directory record Official record
Conditions
Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests, Telemedicine, Time of Death, Time Perception, Time Reaction, Time Efficiency, Time Management, Population, Population Groups, Epidemic Disease, Pandemic, Sex Behavior, Sex Characteristics, Sex Hormone, Cardio-pulmonary, Surgical, Drugs of Abuse, Health Risks, Clinical Outcomes
Interventions
No Study-Assigned Intervention
Other
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2076
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1

NCT00158288
View directory record Official record
Conditions
Behavior Therapy, Cocaine, Contingency Management, Heroin Dependence, LAAM, Opioid Dependence, Substance-Related Disorders, Alcohol & Drug Use
Interventions
LAAM
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 55 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2001
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Healthy Teen Girls: HIV Risk Reduction

NCT00787696
View directory record Official record
Conditions
HIV-infection/Aids
Interventions
Cognitive-behavioral HIV/STD risk reduction
Behavioral
Lead sponsor
Mississippi State University
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
333 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Columbia, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 20, 2011 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Intranasal Delivery of Testosterone and Its Effect on Doping Markers

NCT02611154
View directory record Official record
Conditions
Abuse of Anabolic Steroids
Interventions
Testosterone
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Intervention vs. Delayed Computerized Brief Intervention

NCT01936623
View directory record Official record
Conditions
Drug Abuse
Interventions
Computerized Brief Intervention
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Edgewood, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Results available

Study of the Medication Prazosin for Alcohol Dependence

NCT00762710
View directory record Official record
Conditions
Alcoholism
Interventions
Prazosin medication, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional

Home Based Treatment for Drug Use in Early Adolescents

NCT00280228
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
Interventions
Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
11 Years to 14 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2011 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 3 Interventional Results available

Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder

NCT03078075
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
Naltrexone: Vivitrol®, Placebo (PLB) Injectable, Bupropion: Wellbutrin XL®, Placebo (PLB) Oral
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
8
States / cities
Los Angeles, California • San Francisco, California • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Neurological Influences on Drug Prevention Intervention

NCT00198939
View directory record Official record
Conditions
Youths At-risk for Drug Use/Abuse
Interventions
Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 15 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2012 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional

CRAFT Behavior Therapy: Treatment Entry Component

NCT00842036
View directory record Official record
Conditions
Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Interventions
Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 21, 2026, 10:14 AM EDT
Not listed Not applicable Interventional

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

NCT01621711
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Substance, Addiction, Alcohol Abuse
Interventions
Linkage patient activation intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
504 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 21, 2026, 10:14 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)

NCT07661823
View directory record Official record
Conditions
Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
Interventions
AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
Behavioral
Lead sponsor
Veterans Recovery Network Inc.
Other
Eligibility
17 Years to 99 Years
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2045
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Interactive Motivational Media for Perinatal Drug Abuse - 3

NCT00230048
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Brief computer-delivered intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2012 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Disulfiram Interactions With HIV Medications: Clinical Implications

NCT00878306
View directory record Official record
Conditions
HIV Infections, Drug Abuse
Interventions
Disulfiram, Disulfiram + Efavirenz, Disulfiram + Atazanavir, Disulfiram + Ritonavir
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 6, 2014 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Levetiracetam (Keppra) on Alcohol Consumption

NCT01168687
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Levetiracetam (Keppra), Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 50 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2020 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse

NCT00248092
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
Interventions
NRP104
Drug
Lead sponsor
New River Pharmaceuticals
Industry
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2007 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.

NCT02325011
View directory record Official record
Conditions
Healthy Subjects
Interventions
Sativex® (Treatment A), Sativex® and fluconazole concomitantly (Treatment B)
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of Smoked THC and CBD in Men and Women

NCT05037487
View directory record Official record
Conditions
Drug Abuse, Intoxication by Drug, Impairment
Interventions
Placebo Cannabis, 20 mg CBD Cannabis, 20 mg CBD + 20 mg THC Cannabis, 20 mg THC Cannabis
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Data-driven Identification for Substance Misuse

NCT03833804
View directory record Official record
Conditions
Substance Use, Substance Abuse, Substance-Related Disorders
Interventions
Processing of clinical notes in the EHR data collected during routine care
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
64,996 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 21, 2026, 10:14 AM EDT
Completed Phase 4 Interventional

Buprenorphine and Integrated HIV Care

NCT00317460
View directory record Official record
Conditions
Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS, HIV Infections
Interventions
Physician Management, Counseling
Other · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 21, 2026, 10:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Young Adult Tobacco/Nicotine and Cannabis Co-use

NCT06239350
View directory record Official record
Conditions
Tobacco Use Disorder, Nicotine Dependence
Interventions
Counseling, Contingency management, Text-based support
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 25 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 21, 2026, 10:14 AM EDT