- Conditions
- Dry Eye Disease
- Interventions
- licaminlimab, vehicle of OCS-02, Artificial tears
- Drug · Other
- Lead sponsor
- Oculis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 122 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 5
- States / cities
- Newport Beach, California • Colorado Springs, Colorado • Shelby, North Carolina + 2 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 54
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Dry Eye Disease
- Interventions
- Lotemax, Soothe Tired Eyes Lubricant Eye Drop (Artificial Tears), In Vivo Confocal Microscopy (IVCM)
- Drug · Diagnostic Test
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Dry Eye Disease (DED)
- Interventions
- SYSTANE® PRO, MIEBO™ (Perfluorohexyloctane, PFHO)
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Bloomington, Indiana • Pittsburg, Kansas + 1 more
- Conditions
- Kerato Conjunctivitis Sicca
- Interventions
- KPI-121 Ophthalmic Suspension, Vehicle
- Drug
- Lead sponsor
- Kala Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 901 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 81
- States / cities
- Birmingham, Alabama • Dothan, Alabama • Chandler, Arizona + 64 more
- Conditions
- Dry Eye Disease (DED)
- Interventions
- instillation of NOV03
- Drug
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Dry Eye Disease (DED)
- Interventions
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Device
- Lead sponsor
- Vance Thompson Vision
- Other
- Eligibility
- 22 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Sioux Falls, South Dakota
- Conditions
- Eyelid Diseases, Eyelid Movement Disorders, Dry Eye, Dry Eye Syndromes, Skin Laxity
- Interventions
- TriLift device
- Device
- Lead sponsor
- Lumenis Be Ltd.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Dry Eye Syndromes
- Interventions
- Cyclosporine A, Placebo
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 207 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Lewiston, Maine • Andover, Massachusetts + 1 more
- Conditions
- Dry Eye Disease
- Interventions
- Cyclosporine ophthalmic solution, 0.1%, Saline solution, 0.6%
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 6
- States / cities
- Newport Beach, California • Torrance, California • Garner, North Carolina + 3 more
- Conditions
- Dry Eye Disease
- Interventions
- ST-100 (vezocolmitide), Vehicle
- Drug
- Lead sponsor
- ORA, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Dry Eye Disease
- Interventions
- rhNGF 5 μg/mL, rhNGF 10 μg/mL, Vehicle (Placebo solution)
- Drug
- Lead sponsor
- Dompé Farmaceutici S.p.A
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 317 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 10
- States / cities
- Chandler, Arizona • Torrance, California • Colorado Springs, Colorado + 7 more
- Conditions
- Dry Eye
- Interventions
- Brimonidine Tartrate, Placebos
- Drug
- Lead sponsor
- Ocugen
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 252 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 16
- States / cities
- Newport Beach, California • Rancho Cordova, California • Pompano Beach, Florida + 11 more
- Conditions
- Dry Eye Disease (DED)
- Interventions
- acoltremon 0.003%
- Drug
- Lead sponsor
- Center for Sight Las Vegas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Dry Eye Syndromes, Eye Diseases
- Interventions
- OTX-DED, Controlled Insertion, Collagen Punctal Plug
- Drug
- Lead sponsor
- Ocular Therapeutix, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Dry Eye Disease
- Interventions
- CyclASol topical ocular, eye drops, Vehicle topical ocular, eye drops
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 834 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 27
- States / cities
- Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 23 more
- Conditions
- Dry Eye
- Interventions
- Optive MEGA-3 (OM3)
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Dry Eye Disease (DED)
- Interventions
- OC-01 (varenicline) nasal spray, Placebo (vehicle) nasal spray
- Drug
- Lead sponsor
- Oyster Point Pharma, Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 758 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 22
- States / cities
- Phoenix, Arizona • Newport Beach, California • Fort Collins, Colorado + 18 more
- Conditions
- Dry Eye Disease
- Interventions
- GRF312 5%, Placebo Comparator
- Drug · Other
- Lead sponsor
- Instituto Grifols, S.A.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 10
- States / cities
- Glendale, California • Grove, California • Newport Beach, California + 7 more
- Conditions
- Dry Eye
- Interventions
- Vehicle, SDP-4 Ophthalmic Solution (1.0%)
- Drug
- Lead sponsor
- Silk Technologies, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 153 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 5
- States / cities
- Garden Grove, California • Murrieta, California • Newport Beach, California + 2 more
- Conditions
- Dry Eye Disease (DED)
- Interventions
- Artificial Tear Run-in, licaminlimab, Vehicle of licaminlimab
- Other · Drug
- Lead sponsor
- Oculis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 14
- States / cities
- Aliso Viejo, California • Garden Grove, California • Glendale, California + 11 more
- Conditions
- Dry Eye Disease
- Interventions
- AZR-MD-001, Vehicle
- Drug · Other
- Lead sponsor
- Azura Ophthalmics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 16
- States / cities
- Chandler, Arizona • Glendale, California • Newport Beach, California + 13 more
- Conditions
- Dry Eye Disease (DED)
- Interventions
- NOV03, Placebo
- Drug
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 599 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 29
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Glendale, California + 25 more
- Conditions
- Keratoconjunctivitis Sicca
- Interventions
- Lotemax, Restasis, Soothe® Lubricant Eye Drops
- Drug
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Irvine, California
- Conditions
- Dry Eye Disease (DED)
- Interventions
- DFL24498, Vehicle
- Drug · Other
- Lead sponsor
- Dompé Farmaceutici S.p.A
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 417 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 24
- States / cities
- Chandler, Arizona • Azusa, California • Glendale, California + 21 more