Safety and Efficacy of KPI-121 in Subjects With DED
Public ClinicalTrials.gov record NCT03616899. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-masked, Randomized, Controlled Study of KPI-121 0.25% Ophthalmic Suspension Compared to Vehicle In Subjects With Dry Eye Disease (STRIDE 3)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to determine the efficacy and safety of KPI-121 0.25% ophthalmic suspension compared to vehicle (placebo) in subjects who have a documented clinical diagnosis of dry eye disease. The product will be studied over 14 days, with 1-2 drops instilled in each eye four times daily (QID).
Study identification
- NCT ID
- NCT03616899
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 901 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 10, 2018 (Actual)
- Primary completion
- Feb 5, 2020 (Actual)
- Completion
- Feb 5, 2020 (Actual)
- Last update posted
- Apr 2, 2021
2018 – 2020
United States locations
- U.S. sites
- 81
- U.S. states
- 21
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigator #133 | Birmingham | Alabama | 35294 | — |
| Investigator #278 | Dothan | Alabama | 36301 | — |
| Investigator #146 | Chandler | Arizona | 85224 | — |
| Investigator #148 | Phoenix | Arizona | 85032 | — |
| Investigator #280 | Prescott | Arizona | 86301 | — |
| Investigator #276 | Sun City | Arizona | 85351 | — |
| Investigator #185 | Azusa | California | 91702 | — |
| Investigator #143 | Garden Grove | California | 92843 | — |
| Investigator #147 | Glendale | California | 91204 | — |
| Investigator #272 | Hemet | California | 92545 | — |
| Investigator #155 | Inglewood | California | 90301 | — |
| Investigator #273 | Long Beach | California | 90805 | — |
| Investigator #130 | Mission Hills | California | 91345 | — |
| Investigator #247 | Murrieta | California | 92562 | — |
| Investigator #215 | Newport Beach | California | 92663 | — |
| Site #111 | Rancho Cordova | California | 95670 | — |
| Investigator #271 | Santa Ana | California | 92705 | — |
| Investigator #107 | Torrance | California | 90505 | — |
| Investigator #213 | Westminster | California | 92683 | — |
| Investigator #218 | Littleton | Colorado | 80120 | — |
| Investigator #184 | Brooksville | Florida | 34613 | — |
| Investigator #262 | Delray Beach | Florida | 33484 | — |
| Investigator #279 | Fort Myers | Florida | 33901 | — |
| Investigator #265 | Jacksonville | Florida | 32256 | — |
| Investigator #157 | Largo | Florida | 33773 | — |
| Investigator #189 | Tampa | Florida | 33603 | — |
| Investigator #136 | Morrow | Georgia | 30260 | — |
| Investigator #268 | Roswell | Georgia | 30076 | — |
| Investigator #266 | Chicago | Illinois | 60616 | — |
| Investigator #187 | Hoffman Estates | Illinois | 60169 | — |
| Investigator #151 | Lake Villa | Illinois | 60046 | — |
| Investigator #128 | Indianapolis | Indiana | 46260 | — |
| Investigator #250 | Indianapolis | Indiana | 46290 | — |
| Investigator #125 | New Albany | Indiana | 47150 | — |
| Investigator #274 | Lexington | Kentucky | 40517 | — |
| Investigator #195 | Louisville | Kentucky | 40206 | — |
| Investigator #168 | Louisville | Kentucky | 40220 | — |
| Investigator #219 | Winchester | Massachusetts | 01890 | — |
| Investigator #267 | Kansas City | Missouri | 64133 | — |
| Investigator #123 | St Louis | Missouri | 63128 | — |
| Investigator #106 | St Louis | Missouri | 63131 | — |
| Investigator #126 | St Louis | Missouri | 63131 | — |
| Investigator #131 | Washington | Missouri | 63090 | — |
| Investigator #281 | Henderson | Nevada | 89052 | — |
| Investigator #275 | Las Vegas | Nevada | 89123 | — |
| Investigator #263 | Las Vegas | Nevada | 89145 | — |
| Investigator #138 | Las Vegas | Nevada | 89148 | — |
| Investigator #105 | New York | New York | 10013 | — |
| Investigator #108 | Rochester | New York | 14618 | — |
| Investigator #132 | Wantagh | New York | 11793 | — |
| Investigator #264 | Asheville | North Carolina | 28803 | — |
| Investigator #217 | Durham | North Carolina | 27704 | — |
| Investigator #149 | Durham | North Carolina | 27710 | — |
| Investigator #102 | High Point | North Carolina | 27262 | — |
| Investigator #163 | Raleigh | North Carolina | 27603 | — |
| Investigator #282 | Southern Pines | North Carolina | 28387 | — |
| Investigator #269 | Cincinnati | Ohio | 45242 | — |
| Investigator #142 | Cincinnati | Ohio | 45247 | — |
| Investigator #137 | Cleveland | Ohio | 44115 | — |
| Investigator #171 | Mason | Ohio | 45040 | — |
| Investigator #224 | Cranberry Township | Pennsylvania | 16066 | — |
| Investigator #156 | Kingston | Pennsylvania | 18704 | — |
| Investigator #200 | Lancaster | Pennsylvania | 17601 | — |
| Investigator #277 | West Mifflin | Pennsylvania | 15122 | — |
| Investigator #240 | Rapid City | South Dakota | 57701 | — |
| Investigator #127 | Memphis | Tennessee | 38119 | — |
| Investigator #270 | Austin | Texas | 78681 | — |
| Investigator #188 | Austin | Texas | 78731 | — |
| Investigator #174 | Cedar Park | Texas | 78613 | — |
| Investigator #140 | El Paso | Texas | 79902 | — |
| Investigator #124 | Houston | Texas | 77055 | — |
| Investigator #259 | Houston | Texas | 77204 | — |
| Investigator #175 | Lakeway | Texas | 78734 | — |
| Investigator #182 | League City | Texas | 77573 | — |
| Investigator #191 | League City | Texas | 77573 | — |
| Site #177 | San Antonio | Texas | 78209 | — |
| Investigator #258 | San Antonio | Texas | 78229 | — |
| Investigator #186 | San Antonio | Texas | 78230 | — |
| Investigator #176 | San Antonio | Texas | 78240 | — |
| Investigator #222 | Layton | Utah | 84041 | — |
| Investigator #119 | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03616899, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2021 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03616899 live on ClinicalTrials.gov.