Phase 3 Study of EBI-005 in Dry Eye Disease
Public ClinicalTrials.gov record NCT01998802. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Double-Masked, Randomized, Controlled, Efficacy and Safety Study of EBI-005 5 mg/mL Topical Ophthalmic Solution Versus Vehicle Contraol In Subjects With Moderate to Severe Dry Eye Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase III double-masked, randomized, controlled study evaluating the efficacy of EBI-005 as compared to vehicle given as a topical ophthalmic solution in each eye to subjects with moderate to severe DED three times daily for 12 weeks. Approximately 730 subjects at up to approximately 50 centers in the United States will be screened, enrolled into the study.
Study identification
- NCT ID
- NCT01998802
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 670 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2014 (Type not available)
- Primary completion
- Mar 2015 (Actual)
- Completion
- Apr 2015 (Actual)
- Last update posted
- Jun 11, 2015
2014 – 2015
United States locations
- U.S. sites
- 45
- U.S. states
- 22
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site | Chandler | Arizona | 85225 | — |
| Investigational Site | Mesa | Arizona | 85208 | — |
| Investigational Site | Little Rock | Arkansas | 72212 | — |
| Investigational Site | Artesia | California | 90701 | — |
| Investigational Site | Mission Hills | California | 91345 | — |
| Investigational Site | Petaluma | California | 94954 | — |
| Investigational Site | Rancho Cordova | California | 95670 | — |
| Investiational Site | San Diego | California | 92115 | — |
| Investigational Site | Torrence | California | 90505 | — |
| Investigational Site | Littleton | Colorado | 80120 | — |
| Investigational Site | Hamden | Connecticut | 06518 | — |
| Investigational Site | Plantation | Florida | 33324 | — |
| Investigational Site | Roswell | Georgia | 30076 | — |
| Investigational Site | Bloomingdale | Illinois | 60108 | — |
| Investigational Site | Indianapolis | Indiana | 46260 | — |
| Investigational Site | Indianapolis | Indiana | 46290 | — |
| Investigational Site | New Albany | Indiana | 47150 | — |
| Investigational Site | Lexington | Kentucky | 40509 | — |
| Investigational Site | Louisville | Kentucky | 40206 | — |
| Investigational Site | Louisville | Kentucky | 40217 | — |
| Investigational Site | Bangor | Maine | 04401 | — |
| Investigational Site | Boston | Massachusetts | 02114 | — |
| Investigational Site | Winchester | Massachusetts | 01890 | — |
| Investigational Site | Chesterfield | Missouri | 63017 | — |
| Investigational Site | Des Peres | Missouri | 63131 | — |
| Investigational Site | Kansas City | Missouri | 64111 | — |
| Investigational Site | St Louis | Missouri | 63131 | — |
| Investigational Site | Washington | Missouri | 63090 | — |
| Investigational Site | Las Vegas | Nevada | 89148 | — |
| Investigational Site | New York | New York | 10036 | — |
| Investigational Site | Rochester | New York | 14618 | — |
| Investigational Site | Wantagh | New York | 11793 | — |
| Investigational Site | High Point | North Carolina | 27262 | — |
| Investigational Site | Cleveland | Ohio | 44115 | — |
| Investigational Site | Cranberry Township | Pennsylvania | 16066 | — |
| Investigational Site | Lancaster | Pennsylvania | 17601 | — |
| Investigational Site | Pittsburgh | Pennsylvania | 15213 | — |
| Investigational Site | Rapid City | South Dakota | 57701 | — |
| Investigational Site | Memphis | Tennessee | 38119 | — |
| Investigational Site | Houston | Texas | 77034 | — |
| Investigational Site#2 | Houston | Texas | 77055 | — |
| Investigational Site | League City | Texas | 77573 | — |
| Investigational Site | San Antonio | Texas | 78209 | — |
| Investigational Site# 2 | San Antonio | Texas | 78229 | — |
| Investigational Site | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01998802, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2015 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01998802 live on ClinicalTrials.gov.