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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dystonia, Focal Clear all
Completed Phase 2 Interventional

Motor Training to Treat Hand Dystonia

NCT00021853
View directory record Official record
Conditions
Focal Dystonia
Interventions
constraint-induced movement therapy
Behavioral
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 1:35 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Depotentiation in People With Focal Hand Dystonia

NCT02106936
View directory record Official record
Conditions
Focal Dystonia, Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Phase 2 Interventional Results available

Amlodipine Plus Botulinum Toxin for Focal Dystonia

NCT00015457
View directory record Official record
Conditions
Focal Dystonia
Interventions
Amlodipine plus Botulinum toxin
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 31, 2013 · Synced Jul 22, 2026, 1:35 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Loss of Depotentiation in Focal Dystonia

NCT03206112
View directory record Official record
Conditions
Focal Dystonia, Healthy Volunteers
Interventions
PAS25, PAS10, PAS25-cTBS150
Other
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Jul 22, 2026, 1:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Brain Networks in Dystonia

NCT03042962
View directory record Official record
Conditions
Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia, Craniofacial Dystonia, Blepharospasm Oromandibular Dystonia
Interventions
MRI, Blood draw
Other · Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
21 Years to 80 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Jul 22, 2026, 1:35 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Deep Brain Stimulation Surgery for Focal Hand Dystonia

NCT02911103
View directory record Official record
Conditions
Dystonia, Focal Dystonia, Musician's Dystonia
Interventions
DBS surgery, Medtronic Activa Rechargeable System
Procedure · Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
22 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Motor Features of Cervical Dystonia (CD)

NCT03471923
View directory record Official record
Conditions
Cervical Dystonia, Movement Disorders, Focal Dystonia, Signs and Symptoms, Nervous System Diseases, Neurologic Manifestations, Neuromuscular Manifestations, Spasmodic Torticollis
Interventions
Neurological Examination, Assessment of Non-Motor Features
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia

NCT02334683
View directory record Official record
Conditions
Spasticity, Focal Dystonia, Tremor, Limb
Interventions
Electrical stimulation, Ultrasound
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Bethesda, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Phase 4 Interventional Results available

Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia

NCT00208091
View directory record Official record
Conditions
Focal Dystonia
Interventions
Botulinum toxin, type B
Drug
Lead sponsor
Columbia University
Other
Eligibility
25 Years to 69 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Jul 22, 2026, 1:35 PM EDT
Recruiting Phase 2 Interventional

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

NCT07304089
View directory record Official record
Conditions
Dystonia
Interventions
VIM0423, VIM0423 Placebo
Drug
Lead sponsor
Vima Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
37
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Sun City, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 22, 2026, 1:35 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Transcranial Magnetic Stimulation for Focal Hand Dystonia

NCT01792336
View directory record Official record
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational

Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia

NCT00713414
View directory record Official record
Conditions
Spasmodic Dysphonia, Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Phase 1 Interventional Results available

Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand Dystonia

NCT01884064
View directory record Official record
Conditions
Dystonia, Focal, Task-specific
Interventions
rTMS, Sham rTMS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Transcranial Magnetic Stimulation (TMS) Studies of Dystonia

NCT00017875
View directory record Official record
Conditions
Dystonic Disorder, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Phase 2 Interventional Results available

Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand

NCT02107261
View directory record Official record
Conditions
Dystonia
Interventions
incobotulinumtoxin A, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational

Neuropathology of Spasmodic Dysphonia

NCT00118586
View directory record Official record
Conditions
Voice Disorders, Spasmodic Dysphonia, Healthy, Movement Disorder, Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 7, 2022 · Synced Jul 22, 2026, 1:35 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Brain Changes in Blepharospasm

NCT00487383
View directory record Official record
Conditions
Dystonia, Focal Dystonia, Cerebellar Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 85 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Jul 22, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional

MRgFUS Pallidotomy for the Treatment of Task Specific Focal Hand Dystonia (TSFD)

NCT06367608
View directory record Official record
Conditions
Task-Specific Focal Dystonia
Interventions
ExAblate Transcranial treatment
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational

Association Between Focal Dystonia and Complex Regional Pain Syndrome

NCT00595439
View directory record Official record
Conditions
Focal Dystonia, Peripheral Nervous System Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiology of Task-Specificity of Focal Hand Dystonia

NCT00309010
View directory record Official record
Conditions
Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Surround Inhibition in Patients With Dystonia

NCT00029601
View directory record Official record
Conditions
Dystonic Disorders, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 1:35 PM EDT
Completed No phase listed Observational

Validating a New Writer s Cramp Scale

NCT01579266
View directory record Official record
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Jul 22, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

NCT06036199
View directory record Official record
Conditions
Cerebral Palsy, Dyskinetic, Secondary Dystonia
Interventions
Focused Ultrasound Pallidotomy
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
8 Years to 22 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 1:35 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm

NCT00942851
View directory record Official record
Conditions
Focal Dystonia
Interventions
Acetyl-Hexapeptide Topical Treatment, placebo
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 5, 2012 · Synced Jul 22, 2026, 1:35 PM EDT