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Showing 1–24 of 209 matching trials from the live ClinicalTrials.gov search.
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiology of Task-Specificity of Focal Hand Dystonia

NCT00309010
Conditions
Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
Interventions
Glycerol Tributyrate
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Cervical Dystonia, Blepharospasm, Limb Dystonia, Hemifacial Spasm, Spasticity, Muscle, Fragments of Torsion Dystonia
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Not applicable Interventional

tDCS for Laryngeal Dystonia

NCT06830174
Conditions
Laryngeal Dystonia
Interventions
Starstim system
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Focal Dystonia
Interventions
constraint-induced movement therapy
Behavioral
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Activa RC
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
7 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Cincinnati, Ohio • Nashville, Tennessee + 2 more
Conditions
Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia
Interventions
Infinity DBS System with MR Conditional labelling
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
9
States / cities
Tucson, Arizona • Aurora, Colorado • Littleton, Colorado + 6 more
Completed No phase listed Observational Accepts healthy volunteers

Brain Changes in Patients With Focal Hand Dystonia

NCT00306865
Conditions
Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated Phase 2 Interventional Results available

Study of the Oral Treatment MTR-601 in Cervical Dystonia

NCT06830642
Conditions
Cervical Dystonia
Interventions
MTR-601, Placebo
Drug
Lead sponsor
Motric Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
17
States / cities
Phoenix, Arizona • Fountain Valley, California • Los Angeles, California + 14 more
Conditions
Cervical Dystonia
Interventions
ABP-450
Drug
Lead sponsor
AEON Biopharma, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
20
States / cities
Phoenix, Arizona • Fountain Valley, California • Fresno, California + 16 more
Completed Phase 1Phase 2 Interventional Results available

Dysport for the Treatment of OMD

NCT01921270
Conditions
Oral Dystonia, Tardive Dystonia
Interventions
Low Dose - AbobotulinumtoxinA
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Essential Tremor, Parkinson's Disease, Dystonia
Interventions
WINCS
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Cervical Dystonia, Telemedicine
Interventions
Telemedicine follow-up visit
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Results available

Chronic Effects of DBS in Parkinson's Disease and Dystonia

NCT01934296
Conditions
Parkinson's Disease, Isolated Dystonia
Interventions
Activa PC+S
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
22 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
San Francisco, California
Not listed Phase 1Phase 2 Interventional

ASIS for Botox in Cervical Dystonia

NCT02074293
Conditions
Cervical Dystonia Adults ,, Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus.
Interventions
Gadolinium, Efficacy of Botox intramuscularly at Week 6, Efficacy of Botox intramuscularly at Week 12, Efficacy of Botox intramuscularly at Week 18, Efficacy of Botox intramuscularly at Week 24, Efficacy of Botox intramuscularly at Week 30, Efficacy of Botox subdermally at Week 6, Efficacy of Botox subdermally at Week 12, Efficacy of Botox subdermally at Week 18, Efficacy of Botox subdermally at Week 24, Efficacy of Botox subdermally at Week 30, Adverse Reactions of Botox intramuscularly, Adverse Reactions of Botox subdermally
Drug
Lead sponsor
li nguyen
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Westminster, California
Completed No phase listed Observational Accepts healthy volunteers

Sensory Training to Treat Focal Dystonia

NCT00006336
Conditions
Dystonic Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Cervical Dystonia
Interventions
Electrodes
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Cerebral Palsy, Hypertonia, Spasticity, Dystonia, Rigidity
Interventions
portable surface electromyography
Device
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 18 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation Therapy for Task-Specific Dystonia

NCT06422104
Conditions
Isolated Focal Hand Dystonia
Interventions
Repetitive transcranial magnetic stimulation
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

Non-Motor Features of Cervical Dystonia (CD)

NCT03471923
Conditions
Cervical Dystonia, Movement Disorders, Focal Dystonia, Signs and Symptoms, Nervous System Diseases, Neurologic Manifestations, Neuromuscular Manifestations, Spasmodic Torticollis
Interventions
Neurological Examination, Assessment of Non-Motor Features
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Dystonia
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
University of Southern California
Other
Eligibility
2 Years to 29 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Conditions
Dystonia
Interventions
Deep brain stimulation (DBS)
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
7 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor, Dystonia
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated No phase listed Observational Accepts healthy volunteers

Loss of Depotentiation in Focal Dystonia

NCT03206112
Conditions
Focal Dystonia, Healthy Volunteers
Interventions
PAS25, PAS10, PAS25-cTBS150
Other
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland