Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 373 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: E Cig Use Clear all

Conditions: Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
Interventions: Not listed
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older
Enrollment: 817 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Arterial Stiffness
Interventions: E-cigarette, Nicotine 0%, Menthol Inhalant Product; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 20 Years to 30 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking, Tobacco
Interventions: P2613422, P2611222, P2615522, P2615122, P2615422; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 1,280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 7
States / cities: Maitland, Florida • Atlanta, Georgia • St Louis, Missouri + 4 more

Conditions: Vaping Behaviors, Message Exposure, Young Adults
Interventions: Intervention, Control; Other
Lead sponsor: University of Hawaii; Other
Eligibility: 18 Years to 24 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Healthy Volunteers
Interventions: Use electronic cigarette or smoke conventional cigarette; Other
Lead sponsor: British American Tobacco (Investments) Limited; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Burbank, California

Conditions: Vaping
Interventions: The FDA's The REal Cost vaping prevention ads - Health harms theme, The FDA's The Real Cost vaping prevention ads - Addiction theme, Neutral vaping ads; Behavioral
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 13 Years to 17 Years
Enrollment: 1,565 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Electronic Cigarette Use
Interventions: RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Usual Brand Cigarette, Nicorette White Ice Mint nicotine polacrilex gum; Other
Lead sponsor: Cheerain HK Limited; Industry
Eligibility: 22 Years to 59 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Healthy Volunteers, Vaping Teens
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 13 Years to 120 Years
Enrollment: 726 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Interventions: Acute (24-hour) abstinence, Ad libitum smoking/vaping; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 21 Years to 50 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
Interventions: Product A, Product B, Product C, Product D, Product E, Product N; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 2
States / cities: Springfield, Missouri • Knoxville, Tennessee

Conditions: Cigarette Smoking, Tobacco Use
Interventions: Survey Arm; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 29 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking, Tobacco Use
Interventions: Pod System E-cig, Customizable Tank E-cig, Control; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tobacco Dependence Caused by Cigarettes
Interventions: NJOY ACE commercial e-cigarette; Device
Lead sponsor: University of Nevada, Reno; Other
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Reno, Nevada

Conditions: E-Cig Use, Adolescent Behavior
Interventions: Peer-Led Peer-Elected Intervention, Adult-Led Intervention, Peer-Led Non-Elected Intervention; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: Not listed
Enrollment: 686 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Electronic Cigarette Use
Interventions: RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, RELX ENDS Tobacco and Menthol Flavors; Other
Lead sponsor: Cheerain HK Limited; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 194 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 5
States / cities: Bentonville, Arkansas • Lexington, Kentucky • Springfield, Missouri + 2 more

Conditions: Nicotine Addiction
Interventions: Not listed
Lead sponsor: Rochester Institute of Technology; Other
Eligibility: 21 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Tobacco Use
Interventions: Regulated ad condition, Unregulated ad condition; Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 26 Years
Enrollment: 195 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Electronic Cigarette Use
Interventions: Low strength nicotine e-liquid, High strength nicotine e-liquid; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 55 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation
Interventions: Enhanced E-cigarette Coaching, Quitline treatment as usual; Behavioral
Lead sponsor: Consumer Wellness Solutions; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Vaping, E-Cig Use
Interventions: cytisinicline, Placebo, Behavioral support; Drug · Behavioral
Lead sponsor: Achieve Life Sciences; Industry
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 5
States / cities: Lexington, Kentucky • Boston, Massachusetts • Rochester, New York + 2 more

Conditions: Tobacco Use, Nicotine Dependence, Other Tobacco Product, Tobacco Smoking
Interventions: JUUL 5%, Virginia Tobacco, ENDS product; Other
Lead sponsor: Juul Labs, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Smoking
Interventions: Leading U.S. non-menthol cigarette, Leading U.S. menthol cigarette, Electronic cigarette #1, Electronic cigarette #2, Electronic cigarette #3, U.S. Market-sample electronic cigarettes; Other
Lead sponsor: R.J. Reynolds Vapor Company; Industry
Eligibility: 21 Years to 99 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Stockbridge, Georgia

Conditions: Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking, Incentives, Engagement, Patient, Peer Support, Media Literacy
Interventions: Text-massaging suport, Financial incentive, Media literacy; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years to 29 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Electronic Cigarette Use
Interventions: Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 30 mg/ml nicotine concentration; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Search by objective public record fields.

Patients' Attitudes Toward and Experiences With Buprenorphine Treatment

Vascular Effects of a Single Bout of Electronic Cigarette Use

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status

Pharmacokinetic Study Comparing Nicotine Delivery From E-cigarettes and a Conventional Cigarette in Healthy Subjects

Impact of Vaping Prevention Advertisements

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers

Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol

Vaping and Smoking Project in People With Schizophrenia

CSD201201: Study to Assess Elements of Abuse Liability for Electronic Nicotine Delivery System P12

Electronic Cigarette Use in Young Adult Men and Women

JUUL vs. Mod E-cigarette Study

Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment

Identifying Student Opinion Leaders to Lead E-cigarette Interventions

Characterization of Product Use in Smokers Switching From Cigarettes to a RELX Electronic Nicotine Delivery System

Developing Evidence to Inform Regulatory Policy on Nicotine Content in E-Liquids

Responses to Regulated E-Cigarette Advertisements

Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes

A Study of Cytisinicline for Vaping Cessation in Adult Smokers

A Study to Characterize Puff Topography With Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adult Smokers

Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes

Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation

Assessing Electronic Cigarette Nicotine Flux