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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:59 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 373 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: E Cig Use Clear all

Conditions: Vaping, Social Support
Interventions: Quit the Hit (QTH) Program with Peer Mentoring; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 13 Years to 29 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Vaping Behavior
Interventions: Control ad with dark gray product with tobacco flavor name, Dark gray product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name and image, Colorful (strawberry color) product with strawberry flavor features, Colorful (strawberry color) product with strawberry flavor features and choice claim; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 30 Years
Enrollment: 3,083 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Cancer, Vaping
Interventions: Study assessments; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 15 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Smoking, Tobacco Use, Electronic Cigarette Use
Interventions: P1211216, P1213416, P1213716, P1213616, P1213816, P1211916, P1210016, P1211217, P1213417, P1211222, P1213422, P1213722, P1213622, P1213822, P1211922, P1210022; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 4
States / cities: Stockbridge, Georgia • Lexington, Kentucky • Hickory, North Carolina + 1 more

Conditions: Vaping
Interventions: Vaping prevention video ads; Behavioral
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 13 Years to 20 Years
Enrollment: 3,113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Tobacco Smoking, Healthy Participants, E-cigarette Smokers
Interventions: Felis Domesticus; Biological
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 50 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Electronic Cigarette Use
Interventions: Preferred Juul pod flavor (5% nicotine), Classic Tobacco Juul pod flavor (5% nicotine), Preferred flavor with HWL, Preferred flavor, 3% nicotine, Preferred flavor, 0% nicotine; Other
Lead sponsor: Florida International University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity, Smoking Cessation
Interventions: ENDS, CI, No ENDS, NI; Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 99 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking, Cigarette, Smoking, Tobacco, Nicotine Dependence, Exposure to Toxic Agent
Interventions: Low wattage E cigarette device, High wattage E cigarette device, Usual brand cigarette; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 99 Years
Enrollment: 372 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Electronic Cigarette Use
Interventions: 5% nicotine (Partial Nicotine Reduction), 3% or 2.4% nicotine (Partial Nicotine Reduction), 5% nicotine (Total Nicotine Reduction), 0% nicotine (Total Nicotine Reduction); Other
Lead sponsor: Florida International University; Other
Eligibility: 21 Years to 35 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Electronic Cigarette Use, Cigarette Use, Electronic, Vaping, Cigarette Smoking
Interventions: E-cigarette e-liquid; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tobacco Use
Interventions: Cigarette Brand Switching, E-cigarette Flavor; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Marijuana Dependence
Interventions: Nicotine, Cannabis, PAX Loose Leaf Vaporizer; Drug · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Tobacco Use Disorder
Interventions: Cigarette flavor restricted and e-cigarette flavor restricted, Cigarette flavor restricted and e-cigarette flavor unrestricted, Cigarette flavor unrestricted and e-cigarette flavor restricted, Cigarette flavor unrestricted and e-cigarette flavor unrestricted; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions: AD IT UP media literacy intervention, Usual health education curriculum; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 13 Years to 17 Years
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Substance Withdrawal Syndrome
Interventions: Abstinence from e-cigarettes; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Electronic Nicotine Delivery System Flavors
Interventions: Tobacco product administration and assessment; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years and older
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking, Tobacco Use
Interventions: Low Power, High Power, Low Concentration, High Concentration; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Nicotine Dependence, Tobacco-Related Carcinoma
Interventions: Smartphone app, Text Message, Survey Administration; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years to 30 Years
Enrollment: 1,178 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Survey, E-Cig Use, Smoking Behaviors, Alcohol Drinking, Vaping, Food Intake
Interventions: Not listed
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 3,245 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Tobacco-Related Carcinoma
Interventions: Vaping, Biospecimen Collection, Questionnaire Administration; Other · Procedure
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years to 55 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Nicotine Addiction, Smoking Cessation
Interventions: Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer; Drug · Other
Lead sponsor: Creighton University; Other
Eligibility: 19 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Cannabis, Vaping, Emotion Regulation
Interventions: Virtual reality videogame intervention for vaping prevention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 11 Years to 15 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Use Cessation, Tobacco Use, Electronic Cigarette Use
Interventions: UP2UTeacher; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 14 Years to 15 Years
Enrollment: 520 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

Social Media Vaping Cessation Pilot With Peer Mentors

High Impact E-cigarette Advertisement Features

Study of Vaping Use Among Adolescent and Young Adult Patients With Cancer

CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Delivery System at Three Nicotine Concentrations in an Ambulatory Setting

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model

Assessing the Effect of Flavor on ENDS Users' Experiences and Exposures

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

Examination of Low Wattage and High Wattage E-Cigarettes

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1

Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior

Vaping THC From Electronic Cigarettes

Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace

Media Literacy for High School Tobacco Prevention

Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns

A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users

Assessment of Smoking, Vaping, and Alcohol Consumption Behavior

Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography

e-Cigarettes Versus NRT Gum for Smoking Cessation

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

Development of UP2UTeacher for High School Youth