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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 373 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: E Cig Use Clear all

Conditions: Vaping
Interventions: Vape use survey; Behavioral
Lead sponsor: Methodist Health System; Other
Eligibility: 12 Years and older
Enrollment: 363 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Smoking Cessation; Tobacco Dependence, E-Cig Use, Nicotine Dependence, Other Tobacco Product
Interventions: BREATHE Free Curriculum; Behavioral
Lead sponsor: Augusta University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Electronic Nicotine Delivery Systems, Tobacco Products, Cigarette Smoking
Interventions: EQUIP, Standard Care; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 26 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Smoking, Cigarette, Electronic Cigarette Use
Interventions: Cue Reactivity Task, Computerized Visual Dot Probe, Choice Task; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 34 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking, Cigarette Smoking, Electronic Cigarettes
Interventions: Not listed
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Alcohol Abuse, Nicotine Dependence Tobacco Product
Interventions: E-cig use; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 21 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tobacco Use Disorder
Interventions: Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years and older
Enrollment: 308 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Providence, Rhode Island • Burlington, Vermont

Conditions: Smoking
Interventions: Saliva sample, Urine Sample, Toe nail clippings, Breath carbon monoxide test; Other
Lead sponsor: University of Florida; Other
Eligibility: 6 Years to 17 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Gainesville, Florida • Oklahoma City, Oklahoma

Conditions: Cardiovascular Risk Factor, Nicotine Dependence
Interventions: Electronic Cigarette; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Tobacco Use
Interventions: Brief behavioral counseling; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 21 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Vaping
Interventions: Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message, Social norms graphic message; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 12 Years to 17 Years
Enrollment: 362 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Rochester, New York

Conditions: E-cigarettes, Oxidative Stress, Inflammation
Interventions: e-cigarette, empty (-cigarette sham control); Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cannabis Dependence
Interventions: Biospecimen Collection, Cannabis sativa Extract, Nicotine, Placebo Administration, Questionnaire Administration; Procedure · Drug · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Acute Lung Injury, Pulmonary Injury, Electronic Cigarette Use, Electronic Cigarette Related Lung Injury
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Smoking, Cigarette, Electronic Cigarettes
Interventions: Spectrum Research Cigarettes; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 15 Years to 20 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking, Cigarette, Smoking E-cigarette, Healthy Volunteer
Interventions: [18F]NOS; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 45 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Electronic Cigarette Use
Interventions: Subox Mini C with Avail 18 mg nicotine salt (protonated), Subox Mini C with Avail 18 mg nicotine (unprotonated), Own brand cigarette; Other
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 21 Years to 55 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: E-Cig Use
Interventions: Hyperpolarized Xenon -129 MRI; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Endothelial Dysfunction, Inflammation, Oxidative Stress
Interventions: Traditional hookah smoking, Electronic hookah vaping; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 39 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking Cessation, Electronic Cigarette Use
Interventions: Varenicline, Nicotine patch, Dual Focused Cessation Counseling, Smoking Focused Cessation Counseling, Counseling Intensity: 1 Session, Counseling Intensity: 4 Sessions; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 21 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Electronic Cigarette Use
Interventions: RELX ENDS Tobacco Flavor 1, RELX ENDS Tobacco Flavor 2, RELX ENDS Menthol Flavor 1, RELX ENDS Menthol Flavor 2; Other
Lead sponsor: Cheerain HK Limited; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Burbank, California

Conditions: Smoking, Tobacco Use
Interventions: ENDS Product A with 1.5% nicotine, ENDS Product B with 1.5% nicotine, ENDS Product C with 1.5% nicotine, ENDS Product D with 1.5% nicotine, ENDS Product E with 1.5% nicotine, ENDS Product F with 1.5% nicotine, ENDS Product G with 1.5% nicotine, ENDS Product H with 1.5% nicotine; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: E-Cig Use
Interventions: Remote Contingency Management (CM) for nicotine abstinence, Control; Behavioral · Other
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 20 Years
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Electronic Cigarette Use
Interventions: Social Media Use Reduction; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 25 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Search by objective public record fields.

To Vape or Not to Vape

BREATHE Free Curriculum

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Dual Use of ENDS and Combustible Cigarettes

e-Cigarette - DNA Adducts

Reactions to E-cigs and Alcohol

Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes

Comparison of Smoking and Vaping in Families

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power

Predictors and Consequences of Combustible Cigarette Smokers' Switch to Standardized Research E-Cigarettes

Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents

ECigs, Inflammation and Oxidative Stress

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Electronic Nicotine Delivery Devices and Potential Progression to Acute Lung Injury

Evaluating New Nicotine Standards for Cigarettes - Project 3

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

Effects of Nicotine Salt Aerosol on Cigarette Smokers

Hyperpolarized Xenon-129 MR Imaging of the Lung

The Cardiovascular Effects of Electronic Hookah Vaping

The Avenues Study: Dual Use Cessation

Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers

CSD201202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System P12

Quit Nicotine: E-Cig Cessation Intervention

Effects of Social Media Use on Young Adults' E-Cigarette Use