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ClinicalTrials.gov public records Last synced Oct 26, 2026, 6:19 PM EDT

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Showing 1–24 of 403 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ED Clear all
Active, not recruiting No phase listed Observational

Risk Factors and Outcomes of Ischemic Stroke Associated With Tandem or Isolated Cervical Artery Occlusion in Anterior and Posterior Circulation

NCT06965036
View directory record Official record
Conditions
Acute Ischemic Stroke Related to Tandem Occlusion, Acute Ischemic Stroke Due to Isolated Cervical Artery Occlusion
Interventions
Not listed
Lead sponsor
Azienda Unità Sanitaria Locale della Romagna
Other
Eligibility
Not listed
Enrollment
2,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Phase 4 Interventional Results available

Acetaminophen (APAP) +/- Oxycodone

NCT04122443
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Acetaminophen, Oxycodone
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Clinical Decision Support to Implement ED-initiated Buprenorphine for OUD

NCT03658642
View directory record Official record
Conditions
Clinical Decision Support, Buprenorphine, Opioid-use Disorder
Interventions
Clinical Decision Support (CDS)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
5,047 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
22
States / cities
Birmingham, Alabama • Gardendale, Alabama • Aurora, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit

NCT04068311
View directory record Official record
Conditions
Fall Patients, Delirium, Quality of Life, Functional Status
Interventions
Geriatric Screening tools
Other
Lead sponsor
Ohio State University
Other
Eligibility
65 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional

Can a Rapid 2 Day Followup After Discharge From the ED Reduce Readmissions and Death for Patients 75 Years and Older?

NCT01769495
View directory record Official record
Conditions
Emergencies
Interventions
2-3 day return appointment
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
75 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional

The Impact of Routine Follow-up Contacts After a Pediatric ED Visit for Youth With Suicide Risk

NCT06616701
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Follow up call
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 21 Years
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2025 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients

NCT00116584
View directory record Official record
Conditions
Bronchiolitis
Interventions
heliox, oxygen
Drug
Lead sponsor
University of Louisville
Other
Eligibility
2 Months to 12 Months
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 26, 2026, 6:19 PM EDT
Withdrawn Phase 2 Interventional

N2O for Acute Suicidality and Depression in the ED

NCT05710887
View directory record Official record
Conditions
Suicidal Ideation, Major Depressive Disorder, Treatment Resistant Depression
Interventions
Nitrous oxide gas for inhalation, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 26, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

NCT07120334
View directory record Official record
Conditions
Stroke Recurrence, Type 2 Diabetes, Prediabetes
Interventions
PortionSize Ed + MedDiet Support, Standard of care for Stroke and Prediabetes or T2D
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
30 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ED Recovery Course Online RCT

NCT04557566
View directory record Official record
Conditions
Yoga-Based Recovery Course, Control
Interventions
EBT yoga-based eating disorder course
Behavioral
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
277 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Phase 2 Interventional Results available

Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)

NCT03173456
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
oxycodone/APAP, hydrocodone/APAP, codeine/APAP, 400 ibuprofen/APAP, 800 ibuprofen/APAP
Drug
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years to 64 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 26, 2026, 6:19 PM EDT
Not listed No phase listed Observational

CV-SQuISH-ED: Clinical Validation Study

NCT04933760
View directory record Official record
Conditions
Sepsis, Infection
Interventions
Cytovale IntellipSep test
Diagnostic Test
Lead sponsor
Cytovale, Inc.
Industry
Eligibility
18 Years and older
Enrollment
599 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Baton Rouge, Louisiana • Columbia, Missouri • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional

Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED

NCT06668766
View directory record Official record
Conditions
Difficult Intravenous Access, Midline Catheter, Peripheral Intravenous Catheter, Emergency Department Patient
Interventions
10-cm Single Lumen Mildine, 4.78 cm Long Peripheral Intravenous Catheter
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 26, 2026, 6:19 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

NCT05934669
View directory record Official record
Conditions
Laceration of Skin, Anxiety, Discharge Time
Interventions
Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Year to 5 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 26, 2026, 6:19 PM EDT
Withdrawn Phase 4 Interventional

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

NCT03529331
View directory record Official record
Conditions
Pain
Interventions
Morphine Sulfate Immediate Release, Oxycodone/Acetaminophen, Hydrocodone/Acetaminophen
Drug
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Impact of the IN•Clued Curriculum: An LGBTQ Sex ed Program

NCT04494477
View directory record Official record
Conditions
Teen Pregnancy, STD Prevention
Interventions
The IN•clued program
Behavioral
Lead sponsor
Philliber Research & Evaluation
Other
Eligibility
14 Years and older
Enrollment
1,401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Accord, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Navigation for Adolescents in ED

NCT03239041
View directory record Official record
Conditions
Adolescent Behavior, Social Stress, Emergencies
Interventions
Social navigation team
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
0 Years to 21 Years
Enrollment
395 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief MI Intervention in the ED to Increase Child Passenger Restraint Use

NCT02496481
View directory record Official record
Conditions
Child Restraint Systems, Seat Belts
Interventions
Motivational Interviewing, Tailored brochure
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Video Discharge Instructions for Fever and ED Recidivism

NCT01655251
View directory record Official record
Conditions
Children Who Present to the ED With Minor Febrile Illnesses
Interventions
Intervention
Behavioral
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
8 Weeks to 18 Years
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Phase 4 Interventional Results available

Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the ED With Cutaneous Abscess

NCT01537783
View directory record Official record
Conditions
Cutaneous Abscess
Interventions
Chlorhexidine gluconate, Mupirocin
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 26, 2026, 6:19 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction.

NCT04396795
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Autologous Platelet Rich Plasma, Saline solution
Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 75 Years · Male only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 26, 2026, 6:19 PM EDT
Completed No phase listed Observational

Endotracheal Tube (ETT) Cuff Pressure Study in the Emergency Department (ED)

NCT02160522
View directory record Official record
Conditions
Endotracheal Tube Cuff Pressure Pediatric Emergency
Interventions
Cuffed ETT
Device
Lead sponsor
Edward Ferenczy
Other
Eligibility
Not listed
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 26, 2026, 6:19 PM EDT
Completed No phase listed Observational

A Study to Detect Hyperkalemia Using Smartphone-enabled Electrocardiogram (EKG)

NCT05441852
View directory record Official record
Conditions
Hyperkalemia
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 89 Years
Enrollment
1,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 14, 2023 · Synced Oct 26, 2026, 6:19 PM EDT
Completed No phase listed Observational

Blood Collection of Patient Presenting in the ED and Prescribed a BNP

NCT02614209
View directory record Official record
Conditions
Heart Failure
Interventions
In Vitro diagnostic tests
Device
Lead sponsor
Fujirebio Diagnostics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Baltimore, Maryland • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Oct 26, 2026, 6:19 PM EDT