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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Psilocybin Administration With 5-HT1a Blockade

NCT07565493
Conditions
Psychedelic Effects in Healthy Volunteers
Interventions
Pindolol, Placebo, Psilocybin
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Brain Health With Inner Engineering Meditation

NCT05455814
Conditions
Meditation, Brain; Agenesis
Interventions
Shambhavi Madamudra Kriya
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
20 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Epilepsy, Seizures
Interventions
Not listed
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

Pranayama Practice on the Autonomic Nervous System

NCT03280589
Conditions
Pranayama Effect on Autonomic Nervous System, Respiration Variability Effect on Nervous System
Interventions
Sheetali/Sheekari Pranayama, Sitting Quietly, Deep breathing
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Hypoactive Sexual Desire Disorder
Interventions
Flibanserin, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 74 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Depression
Interventions
Trigeminal Nerve Stimulation
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
SedLine EEG, RRa monitoring
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
19 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Stanford, California
Conditions
Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
Interventions
tACS (aperiodic)
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Major Depressive Disorder
Interventions
apimostinel, Placebo
Drug
Lead sponsor
Syndeio Biosciences, Inc
Industry
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rogers, Arkansas
Conditions
Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
Interventions
transcranial alternating current stimulation (tACS)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Recruiting Not applicable Interventional Accepts healthy volunteers

REcovery From DEXmedetomidine-induced Unconsciousness

NCT06003127
Conditions
Anesthesia, Healthy, Consciousness, Level Altered
Interventions
Transcranial Magnetic Stimulation-Electroencephalography
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Ketamine on ERP/EEG Measures in Healthy Volunteers

NCT04928703
Conditions
Healthy
Interventions
Ketamine
Drug
Lead sponsor
ERP Biomarker Qualification Consortium
Industry
Eligibility
21 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Marlton, New Jersey
Completed Phase 2 Interventional Results available

CX-8998 for Absence Seizures

NCT03406702
Conditions
Epilepsy
Interventions
CX-8998
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
16 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
7
States / cities
Little Rock, Arkansas • Tampa, Florida • Lexington, Kentucky + 4 more
Conditions
Depression, Delirium, Seizures, Cognitive Disorders
Interventions
Ketamine, Electroconvulsive Therapy
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Completed Early Phase 1 Interventional Accepts healthy volunteers

Methylphenidate and Response to Alcohol Cues Pilot Study

NCT06063200
Conditions
Alcohol Use Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Methylphenidate Pill
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Delirium in the Intensive Care Unit
Interventions
Ceribell EEG System
Device
Lead sponsor
Ceribell Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions
RelieVRx, Sham-VR, No-VR (natural history control)
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Neurophysiologic Biomarkers in Rett Syndrome

NCT05932589
Conditions
Rett Syndrome, RTT, Rett Syndrome, Atypical
Interventions
EEG and Auditory and Visual Evoked Potentials (AEP and VEP), Clinical assessment
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 18 Years · Female only
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
6
States / cities
Los Angeles, California • Aurora, Colorado • Brookline, Massachusetts + 3 more
Conditions
Schizophrenia
Interventions
Event-Related Potentials (ERP) and Electroencephalogram (EEG) testing with the COGNISION® System
Device
Lead sponsor
ERP Biomarker Qualification Consortium
Industry
Eligibility
21 Years to 50 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
4
States / cities
Garden Grove, California • Torrance, California • Marlton, New Jersey + 1 more
Conditions
Fragile X Syndrome
Interventions
Speech discrimination
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
24 Months to 4 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates

NCT04050384
Conditions
Infant, Newborn, Infant, Premature, Pain Perception, Pain Measurement, Pain Management, Electroencephalography
Interventions
Baby GentleStick
Device
Lead sponsor
Lance M Relland, MD, PhD
Other
Eligibility
36 Weeks to 56 Weeks
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Autism Spectrum Disorder
Interventions
N-acetylcysteine
Drug
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 13 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Stanford, California
Conditions
PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms
Interventions
Active MeRT Treatment, Sham MeRT Treatment
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Costa Mesa, California • Long Beach, California • San Diego, California + 5 more