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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: EUS Guided Biopsy Clear all
Not listed Not applicable Interventional

Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies

NCT04404101
View directory record Official record
Conditions
Pancreatic Cyst
Interventions
1). EUS-FNA plus MFB, 2). EUS-FNA Alone
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Irvine, California • Aurora, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Phase 4 Interventional

Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms

NCT01673334
View directory record Official record
Conditions
Pancreatic Tumor
Interventions
Fine Needle Aspiration (FNA) and Core biopsy (FNB)
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional

Endoscopic Ultrasound Guided Liver Biopsy

NCT03307811
View directory record Official record
Conditions
Hepatic Cancer, Hepatic Neoplasm, Hepatic Carcinoma
Interventions
22 gauge needle liver biopsy
Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jun 27, 2026, 1:07 PM EDT
Not yet recruiting Not applicable Interventional

Comparison of FNB to EUS-CNB for Pancreatic Lesions

NCT07240818
View directory record Official record
Conditions
Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
Interventions
endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
Device · Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS

NCT02167074
View directory record Official record
Conditions
Pancreatic Masses, Lymph Nodes
Interventions
25G FNA needle, 20G ProCore FNB needle
Device
Lead sponsor
Foundation for Liver Research
Other
Eligibility
18 Years to 100 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
Irvine, California • New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wet Heparin for Obtaining Liver Tissue for EUS Guided Liver Biopsy

NCT03103997
View directory record Official record
Conditions
Liver Diseases
Interventions
EUS-guided liver biopsy
Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Jun 27, 2026, 1:07 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Wet Heparinized Suction for Abdominal Cancer

NCT05041335
View directory record Official record
Conditions
Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus, Cancer of Liver, Cancer
Interventions
wet heparinzed suction, Microsieve, No heparin flush, No microsieve
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Jun 27, 2026, 1:07 PM EDT
Withdrawn Not applicable Interventional

Head to Head Comparison of Two Needles EUS Guided FNB

NCT02534246
View directory record Official record
Conditions
Pancreatic Tumor
Interventions
Ultrasound biopsy needle Echo Tip ProCore, Ultrasound biopsy needle SharkCore
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 12, 2016 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

EUS GUIDED Transduodenal Biopsy Using the 19G Flex

NCT02307253
View directory record Official record
Conditions
Abdominal Neoplasms
Interventions
Expect™19Flex needle (Boston Scientific Corp.,Natick,MA,USA)
Device
Lead sponsor
Catholic University of the Sacred Heart
Other
Eligibility
18 Years to 90 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jun 27, 2026, 1:07 PM EDT
Completed No phase listed Observational

EchoTip AcuCore Post-Market Clinical Study

NCT06358001
View directory record Official record
Conditions
Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma, Malignant Lymphoma, Metastasis, Chronic Pancreatitis, Autoimmune Pancreatitis
Interventions
EchoTip AcuCore
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Orange, California • Denver, Colorado • Gainesville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional

Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses

NCT02911974
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional

19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB)

NCT04806607
View directory record Official record
Conditions
Chronic Liver Disease
Interventions
19G FNB, 22G FNB
Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Jun 27, 2026, 1:07 PM EDT
Recruiting No phase listed Observational

Artificial Intelligence (AI) Cytopathology Trial

NCT05018663
View directory record Official record
Conditions
Pancreatic Solid Lesions
Interventions
Artificial Intelligence software ROSE
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Jun 27, 2026, 1:07 PM EDT
Withdrawn Phase 2 Interventional

Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)

NCT02766842
View directory record Official record
Conditions
Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
Interventions
EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle, SharkCore needle
Procedure · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Jun 27, 2026, 1:07 PM EDT
Terminated Not applicable Interventional Results available

EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors

NCT02282111
View directory record Official record
Conditions
Esophageal Subepithelial Lesions
Interventions
22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Jun 27, 2026, 1:07 PM EDT
Not listed Not applicable Interventional

Randomized Trial for Optimal Number of Passes Required for Molecular Profiling During EUS-FNB of Pancreatic Cancer

NCT05043532
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Neoplasms, Adenocarcinoma of the Pancreas
Interventions
2 passes during EUS-guided fine needle biopsy, 3 passes during EUS-guided fine needle biopsy
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

EUS-guided Fine Needle Aspiration (FNA) With and Without the Use of a Stylet

NCT01316614
View directory record Official record
Conditions
Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods, Endosonography
Interventions
FNA with and without a stylet
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Jun 27, 2026, 1:07 PM EDT
Terminated Not applicable Interventional Results available

Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors.

NCT03264092
View directory record Official record
Conditions
Solid Tumor
Interventions
Endoscopic ultrasound guided fine needle biopsy
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jun 27, 2026, 1:07 PM EDT
Not listed No phase listed Observational

Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue

NCT03140592
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreatic Cyst
Interventions
Biopsy
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Jun 27, 2026, 1:07 PM EDT
Completed No phase listed Observational

On-site Cytopathology EUS-FNA

NCT01386931
View directory record Official record
Conditions
Pancreatic Neoplasms, Pancreatic Cancer
Interventions
EUS-guided FNA performed with on-site Cytopathologist, EUS-guided FNA performed without on-site Cytopathologist
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)

NCT00586313
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
Interventions
Tru-cut biopsy, Tru-cut
Device · Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 16, 2016 · Synced Jun 27, 2026, 1:07 PM EDT
Completed No phase listed Observational

Efficacy, Safety, and Adequacy of EUS-guided Liver Biopsy

NCT04055870
View directory record Official record
Conditions
Chronic Hepatic, Liver Diseases
Interventions
EUS-guided liver biopsy at MDMC
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

22G FNA Needle vs. 22G ProCore Needle

NCT01394159
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
22G ProCore biopsy needle, 22G standard FNA needle
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Jun 27, 2026, 1:07 PM EDT
Completed Not applicable Interventional Results available

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

NCT03408171
View directory record Official record
Conditions
Abnormal Liver Function
Interventions
19-gauge FNA needle, 19-gauge FNB needle
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Jun 27, 2026, 1:07 PM EDT