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Showing 1–24 of 994 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 3 Interventional Results available

Phase 3 Study of OTO-201 in Acute Otitis Externa

NCT02801370
Conditions
Acute Otitis Externa, Swimmer's Ear
Interventions
12 mg ciprofloxacin, Sham Control
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Not yet recruiting Not applicable Interventional

Hearing Loss and Brain Health Study

NCT07288463
Conditions
Hearing Loss, Adult-Onset, Dementia
Interventions
Over-The-Counter (OTC) hearing aid
Device
Lead sponsor
University of Southern California
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Spacer Graft Study

NCT04140734
Conditions
Eyelid Diseases, Eyelid Droop
Interventions
Spacer Graft
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

CI532 - Early Experience Study

NCT02755935
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Cochlear Nucleus CI532
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Months and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Skokie, Illinois • Iowa City, Iowa • Ann Arbor, Michigan + 3 more
Conditions
Otitis Media With Effusion
Interventions
lansoprazole, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Hearing Loss
Interventions
Tinnitus
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Hearing Loss, Sensorineural
Interventions
Electric-Acoustic Stimulation (EAS) Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Palo Alto, California • Miami, Florida • Kansas City, Kansas + 4 more
Conditions
Usher Syndrome, Cochlear Implantation
Interventions
Experimental manipulation of stimulation parameters
Other
Lead sponsor
Ohio State University
Other
Eligibility
1 Year to 85 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Boston, Massachusetts • Columbus, Ohio • Nashville, Tennessee
Completed No phase listed Observational Accepts healthy volunteers

Sight and Hearing Investigation Into Effects on Delirium

NCT06176625
Conditions
Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium, Delirium in Old Age, Delirium of Mixed Origin, Delirium With Dementia, Delirium on Emergence, Delirium, Cause Unknown, Delirium Superimposed on Dementia, Delirium Confusional State, Delirium;Non Alcoholic, Hearing Loss, Bilateral, Hearing Loss, Sensorineural, Hearing Loss, Functional, Hearing Loss, High-Frequency, Hearing
Interventions
Communication Signage, Amplifier Use
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Acute Otitis Media
Interventions
Acute Otitis Media Choice Decision Aid, Usual Care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
6 Months to 18 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Hearing Loss
Interventions
TELLYHealth
Other
Lead sponsor
Healthcare Technologies and Methods, LLC
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Rockville, Maryland
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Regulating Homeostatic Plasticity and the Physiological Response to rTMS

NCT03309696
Conditions
Tinnitus
Interventions
sham tDCS and sham rTMS, sham tDCS and active rTMS, active tDCS and active rTMS
Device
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Completed No phase listed Interventional Results available

Fundamental Asynchronous Stimulus Timing Sound Coding Study

NCT02698787
Conditions
Sensorineural Hearing Loss
Interventions
Experimental sound coding strategy (FAST), Commercially available ACE sound coding strategy
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Terminated No phase listed Observational Accepts healthy volunteers

Exploration of Cortical Neural Network in Patients With Bothersome Tinnitus

NCT01385540
Conditions
Tinnitus
Interventions
Task-Based Functional Magnetic Resonance Imaging (fMRI)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Results available

Auditory-somatosensory Stimulation to Alleviate Tinnitus

NCT02974543
Conditions
Tinnitus
Interventions
Sham Treatment: unimodal auditory stimulation, Active Treatment: Bimodal auditory-somatosensory stimulation
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Ear Drops for Children With Otitis Media

NCT00622518
Conditions
Acute Otitis Media
Interventions
Hyland's earache drops
Drug
Lead sponsor
University of Washington
Other
Eligibility
6 Months to 11 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
Interventions
Pinna-located microphone, Pinna-simulated microphone algorithm
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
8 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Valencia, California
Conditions
Sensori-Neural Deafness, Sensorineural Hearing Loss, Sensorineural Hearing Loss (Disorder), Sensorineural Hearing Loss, Bilateral, Sensorineural Hearing Loss, Profound, Sensorineural Hearing Loss, Severe
Interventions
Acclaim Cochlear Implant
Device
Lead sponsor
Envoy Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
Tucson, Arizona • Seal Beach, California • Gainesville, Florida + 4 more
Conditions
Asthma
Interventions
Antipyrine-benzocaine otic solution, Glycerin with Oxyquinoline Sulfate
Drug · Other
Lead sponsor
Global United Pharmaceutical Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Vestibular Schwannoma, NF2, Neurofibromatosis 2, Acoustic Neuroma, Auditory Tumor
Interventions
lapatinib
Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
7
States / cities
Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 3 more
Conditions
Hearing Loss
Interventions
Community Health Workers and Teleaudiology as a Culturally-Relevant Approach to Improving Access to Hearing Health Care
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nogales, Arizona
Conditions
Hearing Loss
Interventions
Cochlear Implant, Modified Implant Procedure
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Otorrhea
Interventions
Not listed
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 12 Years
Enrollment
1,389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas