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ClinicalTrials.gov public records Last synced Sep 4, 2026, 1:44 PM EDT

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Showing 1–24 of 1,094 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Early Cancer Detection Clear all
Not yet recruiting Not applicable Interventional

Reach and Engagement of GENetic Education, Risk Assessment, and TEsting Feasibility Trial

NCT07787156
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma (PDAC), Family History of Pancreas Cancer, Genetic Testing, Multi-cancer Early Detection
Interventions
Telephone education session, Online educational materials
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Recruiting No phase listed Observational

ExoLuminate Study for Early Detection of Pancreatic Cancer

NCT05625529
View directory record Official record
Conditions
Pancreas Cancer, Exosomes, Extracellular Vesicles, Pancreatic Neoplasms
Interventions
Not listed
Lead sponsor
Biological Dynamics
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 4, 2026, 1:44 PM EDT
Withdrawn Not applicable Interventional

Circulating Tumor DNA Based Minimal Residual Disease Detection for Patients With Early-Stage Breast Cancer

NCT07136493
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Estrogen Receptor-Positive Breast Carcinoma, HER2-Negative Breast Carcinoma, HER2-Positive Breast Carcinoma, Triple-Negative Breast Carcinoma
Interventions
Biospecimen Collection, Electronic Health Record Review, Survey Administration
Procedure · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
5
States / cities
Goodyear, Arizona • Duarte, California • Irvine, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Identification and Validation of Blood-Based Biomarkers for Early Detection of Asymptomatic Lung Cancer in High-Risk Heavy Smokers

NCT06816121
View directory record Official record
Conditions
Lung Cancers
Interventions
Not listed
Lead sponsor
Everest Detection, Inc.
Industry
Eligibility
30 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program

NCT05831358
View directory record Official record
Conditions
Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma
Interventions
Multiple Myeloma M-Protein Analysis, Multiple Myeloma Knowledge Questionnaires
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
50 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Study of Lung Cancer Screening in People With Unexplained Weight Loss

NCT06717334
View directory record Official record
Conditions
Lung Cancer Screening
Interventions
Low Dose CT imaging, blood draws, screening questionnaire
Diagnostic Test · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Maximizing Yield of the Fecal Immunochemical Test for Colorectal Cancer Screening

NCT01634126
View directory record Official record
Conditions
Colorectal Cancer
Interventions
1 FIT kit, 2 FIT kit
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
50 Years to 75 Years
Enrollment
2,761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Overdiagnosis and Breast Cancer Screening Decisions

NCT07071415
View directory record Official record
Conditions
Mammography Screening, Geriatrics, Decision Aid
Interventions
Breast cancer screening decision aid -- low risk, Breast cancer decision aid -- moderate risk, Breast cancer screening decision aid -- high risk, Control condition
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
70 Years and older · Female only
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional

Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up

NCT00697047
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Automated Mailing, Automated Mailing Plus Assisted, Auto Plus Assisted Plus Navigation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
50 Years to 73 Years
Enrollment
4,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 4, 2026, 1:44 PM EDT
Terminated Not applicable Interventional Results available

Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer

NCT00959985
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Compression Sleeve, Short-Stretch Compression Bandage
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 4, 2026, 1:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD

NCT06751576
View directory record Official record
Conditions
High Risk Cancer, Lung Cancer
Interventions
Median LCS
Device
Lead sponsor
Median Technologies
Industry
Eligibility
50 Years to 80 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
3
States / cities
Philadelphia, Pennsylvania • Memphis, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 4, 2026, 1:44 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Prostate Cancer Screening and Dietary Heterocyclic Amines in African American Men

NCT00354497
View directory record Official record
Conditions
Prostate Cancer
Interventions
physiologic testing, study of socioeconomic and demographic variables, evaluation of cancer risk factors, mutation carrier screening, study of high risk factors
Other · Procedure
Lead sponsor
Lawrence Livermore National Laboratory at University of California
Other
Eligibility
50 Years to 70 Years · Male only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2002
U.S. locations
2
States / cities
Livermore, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Sep 4, 2026, 1:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening for Familial Colorectal Cancer (CRC) Patients

NCT00632515
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Up to 60 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Health Service Intervention for the Improvement of Access and Adherence to Colorectal Cancer Screening

NCT04607291
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Community Health Service, Survey Administration
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Sep 4, 2026, 1:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

CESM ABMR Breast Cancer Screening Trial

NCT03517813
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
Contrast-enhanced Spectral Mammography (CESM)
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of Automated Telephone Outreach to Improve Colorectal Cancer Screening

NCT00792285
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Automated Telephone Outreach with Speech Recognition
Behavioral
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
50 Years to 64 Years
Enrollment
80,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 16, 2008 · Synced Sep 4, 2026, 1:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Computer-Based Tailored or Standard Information for Colorectal Cancer Screening

NCT00955188
View directory record Official record
Conditions
Colorectal Cancer
Interventions
computer-assisted intervention, educational intervention, medical chart review
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
50 Years to 79 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
3
States / cities
San Francisco, California • Ann Arbor, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Sep 4, 2026, 1:44 PM EDT
Not listed Phase 1Phase 2 Interventional

Circadian Thermal Sensing to Detect Breast Disease

NCT02511301
View directory record Official record
Conditions
Early-Stage Breast Carcinoma
Interventions
Cyrcadia CBR™ device placement for abnormality screening
Device
Lead sponsor
Cyrcadia Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Mountain View, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional

Lung Cancer Screening: A Multilevel Intervention

NCT03862001
View directory record Official record
Conditions
Lung Cancer
Interventions
LungCARE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

VitalTraq for the Detection of CRS

NCT06415656
View directory record Official record
Conditions
Hematologic Malignancy
Interventions
TempTraq, VitalTraq
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Sustainable Approach to Increasing Cancer Screening

NCT01395459
View directory record Official record
Conditions
Colorectal Cancer, Breast Cancer, Cervical Cancer
Interventions
IVR only, IVR+PCC
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
21 Years to 86 Years
Enrollment
13,675 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Lawrence, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Sep 4, 2026, 1:44 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cone Beam Breast CT for Breast Cancer Screening

NCT05036096
View directory record Official record
Conditions
Breast Cancer
Interventions
CBBCT Imaging, Digital Mammography
Device
Lead sponsor
Koning Corporation
Industry
Eligibility
30 Years and older · Female only
Enrollment
1,024 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
4
States / cities
Port Orange, Florida • Dacula, Georgia • Tifton, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 4, 2026, 1:44 PM EDT
Terminated Not applicable Interventional

Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer

NCT00970645
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
Mediastinoscopy/thoracoscopy, EBUS/EUS
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 17, 2011 · Synced Sep 4, 2026, 1:44 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer

NCT05868486
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions
Biospecimen Collection, Genetic Testing for Cancer Risk, Liquid Biopsy, Magnetic Resonance Imaging of the Whole Body without Contrast, Survey Administration
Procedure · Genetic · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 4, 2026, 1:44 PM EDT