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ClinicalTrials.gov public records Last synced Sep 3, 2026, 11:37 AM EDT

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Showing 1–24 of 252 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Early Detection of Cancer Clear all
Terminated No phase listed Observational

Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease

NCT00813878
View directory record Official record
Conditions
Breast Cancer
Interventions
protein analysis, protein expression analysis, proteomic profiling, diagnostic laboratory biomarker analysis, immunohistochemistry staining method, liquid chromatography, mass spectrometry, fine-needle aspiration, needle biopsy, radiomammography
Genetic · Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Not applicable Interventional

RCT of Screening Strategies Among Patients at High Risk for Developing HCC in a Safety-net Health System

NCT02312817
View directory record Official record
Conditions
Carcinoma, Hepatocellular, Liver Neoplasms
Interventions
Mailed Outreach Invitation, Mailed Outreach Invitation and Patient Navigation
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years and older
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 3, 2026, 11:37 AM EDT
Active, not recruiting Phase 2 Interventional

ChatBot and Activity Monitoring in Patients Undergoing Chemoradiotherapy

NCT05318027
View directory record Official record
Conditions
Lung Cancer, Gastrointestinal Cancer, Head and Neck Cancer
Interventions
ChatBot
Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Not listed No phase listed Observational

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

NCT05987189
View directory record Official record
Conditions
Lung Cancer
Interventions
miLungDx
Diagnostic Test
Lead sponsor
Hummingbird Diagnostics
Industry
Eligibility
50 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 3, 2026, 11:37 AM EDT
Recruiting Not applicable Interventional

Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combined With GRAIL Galleri Testing to Improve Early Detection

NCT05481697
View directory record Official record
Conditions
Unintended Weight Loss
Interventions
GRAIL Galleri
Diagnostic Test
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
40 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 1

NCT06082505
View directory record Official record
Conditions
Cervical Cancer, Breast Cancer
Interventions
Education, Navigation to clinic
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older · Female only
Enrollment
8,262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 3, 2026, 11:37 AM EDT
Recruiting No phase listed Observational

A Study of a Urine Test to Detect Colorectal Cancer

NCT07649057
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Polyp, Rectal Bleeding, CRC
Interventions
3-metabolite biosensor
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates

NCT04474184
View directory record Official record
Conditions
Endometrial Carcinoma
Interventions
Biospecimen Collection, Focus Group, Survey Administration
Procedure · Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 3, 2026, 11:37 AM EDT
Suspended No phase listed Observational

Supporting Informed Decision Making About Multi-cancer Early Detection Testing

NCT06870916
View directory record Official record
Conditions
Multi-cancer Early Detection
Interventions
Multi-cancer Early Detection
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Phase 3 Interventional

Interferon Alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis

NCT00004196
View directory record Official record
Conditions
Melanoma (Skin)
Interventions
recombinant interferon alfa, lymphangiography, Observation
Biological · Procedure · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2007
U.S. locations
4
States / cities
Birmingham, Alabama • Louisville, Kentucky • New Brunswick, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2014 · Synced Sep 3, 2026, 11:37 AM EDT
Terminated No phase listed Observational

Mesothelioma Early Detection by VOCs

NCT04106973
View directory record Official record
Conditions
Pleural Mesothelioma, Asbestos Exposure, Pleural Plaque
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

NCT03071809
View directory record Official record
Conditions
Neoplasms, Non-hematologic - Stage I-III
Interventions
Not listed
Lead sponsor
Lexent Bio, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 3, 2026, 11:37 AM EDT
Completed No phase listed Observational

Detection of Early Metastases in Patients With Stage I Non-small Cell Lung Cancer

NCT00003006
View directory record Official record
Conditions
Lung Cancer
Interventions
reverse transcriptase-polymerase chain reaction, immunohistochemistry staining method
Genetic · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2010
U.S. locations
10
States / cities
Iowa City, Iowa • Baltimore, Maryland • Minneapolis, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Sep 3, 2026, 11:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer

NCT01662609
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Endoscopic Ultrasound (EUS)
Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
30 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2022
U.S. locations
2
States / cities
Tampa, Florida • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Sep 3, 2026, 11:37 AM EDT
Recruiting No phase listed Observational

ExoLuminate Study for Early Detection of Pancreatic Cancer

NCT05625529
View directory record Official record
Conditions
Pancreas Cancer, Exosomes, Extracellular Vesicles, Pancreatic Neoplasms
Interventions
Not listed
Lead sponsor
Biological Dynamics
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Early Phase 1 Interventional

Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasia

NCT01384864
View directory record Official record
Conditions
Barrett's Esophagus, Intraepithelial Neoplasia
Interventions
proflavine
Drug
Lead sponsor
Anandasabapathy, Sharmila, M.D.
Individual
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2016 · Synced Sep 3, 2026, 11:37 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

War on Melanoma™ Public Health & Education Campaign

NCT04611568
View directory record Official record
Conditions
Melanoma
Interventions
Educational Intervention, Health Education, Media Campaign, Survey Administration
Other · Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
12 Years and older
Enrollment
75,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Detection of GEnetic Risk (EDGE)

NCT04746794
View directory record Official record
Conditions
Genetic Predisposition
Interventions
Population-level screening
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
20,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Billings, Montana • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Not applicable Interventional Results available

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

NCT04798664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Removal of Financial Barriers, Financial Incentives, Mobile Health Application
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Oakland, California • Detroit, Michigan • Danville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed No phase listed Observational

Histology Post-Endoscopic Eradication Therapy (EET)

NCT03375060
View directory record Official record
Conditions
Esophageal Reflux, Barrett Esophagus
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Not applicable Interventional Results available

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

NCT01719562
View directory record Official record
Conditions
Cardiac Toxicity, Malignant Neoplasm, Breast Cancer
Interventions
Magnetic resonance imaging, Physical Activity, Healthy Living, Cardiopulmonary Exercise Testing (CPET), Questionnaire Administration
Procedure · Other · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 3, 2026, 11:37 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pancreatic Cancer Early Detection Consortium

NCT04970056
View directory record Official record
Conditions
Pancreas Cancer, Pancreas Cyst, Pancreatic Ductal Adenocarcinoma, Genetic Predisposition
Interventions
Not listed
Lead sponsor
Arbor Research Collaborative for Health
Other
Eligibility
18 Years to 90 Years
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
45
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Burbank, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 3, 2026, 11:37 AM EDT
Completed Phase 3 Interventional Results available

Study to Improve Detection and Early Recurrence Rate in Bladder Cancer Patients Using Hexvix Fluorescence Cystoscopy

NCT00233402
View directory record Official record
Conditions
Bladder Cancer
Interventions
Hexvix, Standard white light cystoscopy
Drug · Procedure
Lead sponsor
Photocure
Industry
Eligibility
18 Years and older
Enrollment
789 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
15
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2013 · Synced Sep 3, 2026, 11:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer

NCT02549534
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Axon Reflexes, Axon Flares, Self-Reported Signs & Symptoms of CIPN
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 3, 2026, 11:37 AM EDT