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ClinicalTrials.gov public records Last synced Jun 26, 2026, 12:49 AM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Study of Cannabidiol and Neuroimaging on Stress

NCT07278505
Conditions
Early Life Adversity, Trauma, Stress
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 25 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
New York, New York
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Remote Mindfulness Training Following Early Life Adversity

NCT05516108
Conditions
Stress, Mindfulness, Early Life Adversity
Interventions
Mindfulness, Coping
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 29 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

The Resilience Clinic Evaluation

NCT05690256
Conditions
Early Life Adversity, Caregiver Stress
Interventions
Resilience Clinic, Enhanced primary care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 5 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
4
States / cities
Oakland, California • San Leandro, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Positive Affect Treatment for Adolescents With Early Life Adversity

NCT06273137
Conditions
Depression
Interventions
Positive affect treatment, Supportive psychotherapy (SUP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
12 Years to 16 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Irvine, California
Completed Not applicable Interventional Accepts healthy volunteers

Remote Mindfulness Training Following Early Life Adversity 2

NCT07085052
Conditions
Stress, Mindfulness, Early Life Adversity
Interventions
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 29 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Anxiety, Depression
Interventions
Growth, Empowerment, and Mindfulness (GEM)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 24 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers

Augmented Mindfulness Training for Resilience in Early Life

NCT04053582
Conditions
Adolescents With Early Life Stress
Interventions
AMT, Sham
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
13 Years to 17 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Collaborative Approach to Examining Adversity and Building Resilience Study

NCT05259436
Conditions
Early Life Adversity, Caregiver Stress
Interventions
Caregiver-child Intervention, Enhanced Primary Care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
4
States / cities
Oakland, California • Richmond, California • San Francisco, California + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

NCT04964726
Conditions
Emotional Dysfunction, Early Life Stress
Interventions
Real-time fMRI dyadic neurofeedback
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
14 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Conditions
Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function, Oxidative Stress, Psychosocial Influence on Cardiovascular Disease
Interventions
Mitoquinone mesylate (MitoQ), Placebo
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Child Development
Interventions
Parental Support Cold Pressor Task
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
6 Years to 9 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Health Experiences & Early Life Disadvantages

NCT02400593
Conditions
Early Life Adversity, Chronic Stress
Interventions
Meditation Workshop
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 64 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Parenting Intervention, Stress, Caregiver Child Relationship, Child Behavior Problem, Mental Health
Interventions
Attachment and Biobehavioral Catch-up (ABC), Waitlist with 4-month delay, then ABC
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, South Carolina
Conditions
Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms, Signs and Symptoms, Psychological Distress, Psychological
Interventions
Mindfulness-based intervention, up to 5 minutes 0-3 times/day
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Francisco, California