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ClinicalTrials.gov public records Last synced Nov 12, 2026, 9:41 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Early Osteoarthritis Clear all

Conditions: Ankle Osteoarthritis
Interventions: Not listed
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 85 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Osteoarthritis of Knee, Edema, Wounds and Injuries
Interventions: ODIN1, Standard Care, Diagnostic Device Testing; Device · Other
Lead sponsor: Bioelectric Research Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 2
States / cities: Las Vegas, Nevada

Conditions: Knee Osteoarthritis
Interventions: Compex Rehab; Device
Lead sponsor: Orthopaedic Research Foundation; Other
Eligibility: 45 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Greenwood, Indiana

Conditions: Osteoarthritis
Interventions: Variable-Stiffness Shoe; Device
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Osteoarthritis, Knee
Interventions: Zero Degree Knee Positioner; Device
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 40 Years to 80 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Pain, Osteoarthritis
Interventions: Canal Block and Capsular Injection, Femoral with Tibial Nerve Block; Procedure
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years to 80 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Osteoarthritis, Knee
Interventions: Device: Robotic MAKO total knee, FocusMotion knee brace, Fitbit tracking device, FocusMotion app; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Creve Coeur, Missouri

Conditions: Knee Osteoarthritis
Interventions: focus motion knee brace; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 95 participants
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease, Osteochondral Lesion, Hip Dysplasia
Interventions: ReNew Hip Implant; Device
Lead sponsor: Cytex Therapeutics, Inc.; Other
Eligibility: 14 Years to 64 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Osteoarthritis, Osteoarthritis, Knee, Arthritis, Degenerative, Osteoarthrosis, Osteoarthrosis Deformans
Interventions: Bupivacaine Liposome Injection, Indwelling femoral nerve block; Drug
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: San Diego, California

Conditions: Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD), Early Osteoarthritis
Interventions: osteochondral scaffold implant, SSOC; Device · Procedure
Lead sponsor: Fin-Ceramica Faenza Spa; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 9
States / cities: La Mesa, California • Steamboat Springs, Colorado • Oak Brook, Illinois + 6 more

Conditions: Osteoarthritis
Interventions: Synvisc-One (G-F 20); Device
Lead sponsor: Anthony Luke; Other
Eligibility: 30 Years to 50 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Osteoarthritis, Post-traumatic; Arthrosis
Interventions: methylprednisolone acetate, active comparator; Drug
Lead sponsor: New Lexington Clinic; Other
Eligibility: 18 Years to 95 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Obesity
Interventions: Group 1 (First trimester ultrasound), Group 2 (Second trimester anatomy ultrasound); Diagnostic Test
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Osteoarthritis, Knee
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 30 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Osteoarthritis, Hip
Interventions: isobaric bupivacaine, hyperbaric bupivacaine, isobaric mepivacaine; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 84 Years
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 2
States / cities: Bensalem, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Osteoarthritis
Interventions: Physical training program, Self-management training program, Physical training and self-management training programs; Other · Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 35 Years to 64 Years
Enrollment: 294 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Post-Traumatic Osteoarthritis of Knee
Interventions: ERIPTO Protocol, BMAC Only; Combination Product · Biological
Lead sponsor: Affinity Health Research Institute; Other
Eligibility: 25 Years to 60 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Aurora, Illinois • Oak Brook, Illinois

Conditions: Knee Osteoarthritis
Interventions: Triathlon total knee system; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Osteoarthritis, Post-traumatic Osteoarthritis
Interventions: amobarbital/Gel-One (one dose), Placebo (single dose), amobarbital/Gel-One (two doses), Placebo (two doses); Drug
Lead sponsor: J L Marsh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Osteoarthritis
Interventions: Neuromuscular Electrical Stimulation (NMES), Standard Rehabilitation Protocol; Device · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years to 85 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Pain, Osteoarthritis
Interventions: Canal Block and Capsular Injection, Femoral Nerve Block with Tibial Nerve Block; Procedure
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years to 80 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Knee Osteoarthritis
Interventions: Lipogems Device PLUS debridement, Debridement only; Device · Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 70 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

TAR 2 Weeks vs 6 Weeks Post-Operative Weight-Bearing

Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery

Early Postoperative Compex Rehab NMES Use for Total Knee Arthroplasty Patients

A Biomarker Stress Test for Detection of Early Osteoarthritis

Zero Degree Knee Positioner for Improved Earley Knee Extension Following Total Knee Arthroplasty

Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement

MAKO Total Knee Artroplasty

Early Outcomes of MAKO Medial Unicompartmental Knee Arthroplasty

Early Feasibility Study of Cartilage Defect Repair

Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty

MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee

Synvisc-One for Younger, Active Patients With Osteoarthritis

Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?

Early Anatomy Scan for Evaluation of Obese Pregnant Women (EASE-O)

Mobile Technology to Measure Knee Health in Osteoarthritis

3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty

Community-Based Programs for Improving Physical Function in People With Early Knee Osteoarthritis

Early Regenerative Intervention for Post-Traumatic Osteoarthritis

Cemented vs Cementless TKA

Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

Early Neuromuscular Electrical Stimulation For Quadriceps Muscle Activation Deficits Following Total Knee Replacement

Early Ambulation After Adductor Canal Block for Total Knee Arthroplasty

Lipogems Prospective Study