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Conditions: Preterm Infant, Cerebral Palsy
Interventions: Supporting Play Exploration and Developmental Intervention (SPEEDI); Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: Up to 6 Months
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 2
States / cities: Los Angeles, California • Richmond, Virginia

Conditions: Prematurity, Necrotizing Enterocolitis
Interventions: Assessment of urinary iFABP, Administration of enteral feedings; Other
Lead sponsor: Loma Linda University; Other
Eligibility: Up to 2 Days
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Heart Transplantation, Kidney Transplantation, Liver Transplantation, Lung Transplantation
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: Up to 70 Years
Enrollment: 313 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 5
States / cities: Chicago, Illinois • Ithaca, New York • New York, New York + 2 more

Conditions: Premature Birth
Interventions: Vaginal Progesterone gel., fetal fibronectin swab., Placebo gel; Drug · Procedure
Lead sponsor: Obstetrix Medical Group; Industry
Eligibility: 18 Years to 60 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: San Jose, California

Conditions: Child Rearing, Reproductive Behavior, Risk Reduction Behavior
Interventions: home visitation; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: Female only
Enrollment: 609 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2012
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Hyperandrogenemia, Obesity, Polycystic Ovary Syndrome
Interventions: Hydrocortisone, dexamethasone, Cosyntropin, rhCG; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 7 Years to 16 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Miscarriage in First Trimester
Interventions: Hysteroscopic resection, Manual Vacuum Aspiration; Procedure
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Preterm Delivery
Interventions: Not listed
Lead sponsor: Esoterix Genetic Laboratories, LLC; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: Westborough, Massachusetts • Santa Fe, New Mexico

Conditions: PCOS (Polycystic Ovary Syndrome), Puberty, Insulin Resistance, Physical Activity
Interventions: ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 8 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Hemolytic Disease of the Fetus and Newborn
Interventions: M281; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 8
States / cities: San Francisco, California • New York, New York • Cincinnati, Ohio + 5 more

Conditions: Early Stage Triple-Negative Breast Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Cervical Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Endometrial Carcinoma, Metastatic Esophageal Carcinoma, Metastatic Liver Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Skin Neoplasm, Metastatic Malignant Solid Neoplasm, Resectable Lung Non-Small Cell Carcinoma, Early Stage Lung Non-Small Cell Carcinoma, Resectable Malignant Solid Neoplasm, Resectable Triple-Negative Breast Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Cervical Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8, Recurrent Cervical Carcinoma, Recurrent Colorectal Carcinoma, Recurrent Endometrial Carcinoma, Recurrent Esophageal Carcinoma, Recurrent Liver Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Recurrent Malignant Skin Neoplasm, Recurrent Malignant Solid Neoplasm
Interventions: Biospecimen Collection, Tissue Collection; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Diabetes, Pregnancy
Interventions: Minimum intervention control group, Treatment for glucose intolerance; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: San Jose, California • Stanford, California

Conditions: Stress Urinary Incontinence
Interventions: Urodynamic testing with and without pudendal nerve stimulation; Diagnostic Test
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Turner Syndrome
Interventions: Not listed
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 2 Weeks to 2 Years
Enrollment: 295 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2014
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Thrombotic Microangiopathies, Atypical Hemolytic Uremic Syndrome, Multiple Organ Dysfunction Syndrome
Interventions: Eculizumab; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: Los Angeles, California • Cincinnati, Ohio • Philadelphia, Pennsylvania

Conditions: Chronic Kidney Disease
Interventions: Niacin, Active Placebo; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 21 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Diabetes Mellitus, Type 1, Nephropathy, Diabetic Nephropathies, Juvenile Diabetes, Diabetes Mellitus Complication, Autoimmune Diabetes, Type 1 Diabetes Mellitus
Interventions: Aminohippurate Sodium Inj 20%, Iohexol Inj 300 mg/mL; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 21 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Acute Kidney Injury
Interventions: Discarded urine sample; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 8 Years
Enrollment: 305 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Kidney Injury
Interventions: Shear Wave Elastography; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Early Pregnancy Loss, Delayed Pregnancy Loss
Interventions: CCT-102 A and CCT-102 B; Combination Product
Lead sponsor: Conceptra Biosciences, LLC; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 15
States / cities: Tucson, Arizona • San Fernando, California • Panama City, Florida + 12 more

Conditions: Gestational Diabetes, Glucose Intolerance
Interventions: Non-intervention group, Face to face, Telehelath Group; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Endometriosis
Interventions: Not listed
Lead sponsor: Biofourmis Singapore Pte Ltd.; Industry
Eligibility: 21 Years to 50 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Phoenix, Arizona • Rochester, Minnesota

Conditions: Pregnancy
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 0 Years to 39 Years
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Kidney Failure, Hemodialysis Fistula Thrombosis
Interventions: Clopidogrel, Placebo; Drug
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years and older
Enrollment: 877 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 9
States / cities: Birmingham, Alabama • Iowa City, Iowa • Portland, Maine + 6 more

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Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention

Prediction of NEC With Urinary iFABP

Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival

Vaginal Progesterone in Twins With Short Cervix

Age 12 Follow-up of Early Preventive Intervention (Memphis)

Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction

Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

Preterm Delivery Risk Prediction by Measurement of Prenatal Serum Screening Markers

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Pregnant Women at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

Early Screening and Treatment of Women With Prediabetes in Pregnancy

Effect of Peri-Urethral Stimulation on Intra-Urethral Pressure

Sex Differences in Early Brain Development; Brain Development in Turner Syndrome

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Niacin and Endothelial Function in Early CKD

Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function

Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury

The Biosonographic Index

CCT-102 or Expectant Management in Delayed Pregnancy Loss

Postpartum Weight Loss and Exercise (PRIDE)

Objective Pain Measurement Using a Wearable Biosensor and a Mobile Platform in Patients With Endometriosis

The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy

Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis