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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Edentulous Mouth Clear all
Not yet recruiting Not applicable Interventional

Comparative Study of Denture Fabrication Techniques

NCT07525011
View directory record Official record
Conditions
Complete Edentulism
Interventions
Traditional Complete Denture Fabrication, Easdent Digital Complete Denture Fabrication
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Results available

A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers

NCT03709810
View directory record Official record
Conditions
Denture Retention
Interventions
Marketed Denture Adhesive (Super Poligrip Max Seal), No Adhesive
Combination Product · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Abutment Macro Design and Peri-implant Tissues

NCT02546713
View directory record Official record
Conditions
Edentulous
Interventions
Abutment with concave subcritical contour, Abutment with convex subcritical contour
Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Sep 14, 2026, 10:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Implant Stability in Autogenous Mineralized and Demineralized Dentin Grafts

NCT05219305
View directory record Official record
Conditions
Edentulous Alveolar Ridge
Interventions
Dental Implant Placement
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges

NCT03468998
View directory record Official record
Conditions
Alveolar Ridge Augmentation, Alveolar Ridge Preservation
Interventions
Socket Grafting with small particle allograft, Socket Grafting with large particle allograft, Lateral ridge augmentation with small particle allograft, Lateral ridge augmentation with large particle allograft
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional

A Clinical Study of the T3 Short Dental Implant System

NCT04237545
View directory record Official record
Conditions
Edentulous Jaw
Interventions
T3 short and restoration (prosthesis), T3 standard length and restoration (prosthesis)
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Dearborn Heights, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Study on ASTRA TECH Implant System, OsseoSpeed™ Implants in Patients Missing All Teeth in the Upper Jaw, Restored With Provisional Teeth Within 24 Hours

NCT00711022
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
ASTRA TECH Implant System, OsseoSpeed™, all dimensions.
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing the Healing With or Without a Barrier Membrane

NCT02798887
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Ridge preservation
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 14, 2026, 10:21 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

An Observational Clinical Case Series Study to Assess Fit and Quality of Full Dentures Fabricated by AM

NCT04023006
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Removable prostheses
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 14, 2026, 10:21 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

NCT07613047
View directory record Official record
Conditions
Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
Interventions
Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 14, 2026, 10:21 PM EDT
Completed No phase listed Observational

A Clinical Study of the TSV Dental Implant System

NCT04236336
View directory record Official record
Conditions
Edentulous Jaw
Interventions
TSV dental implant
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
New Orleans, Louisiana • Ann Arbor, Michigan • Livonia, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implant Placement With Simultaneous Gum Grafting

NCT01431144
View directory record Official record
Conditions
Edentulous
Interventions
connective tissue autograft, connective tissue allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The TREFOIL Concept 5 Year Clinical Investigation

NCT02940353
View directory record Official record
Conditions
Edentulous or Failing Dentition Mandible
Interventions
TREFOIL concept
Device
Lead sponsor
Nobel Biocare
Industry
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Incidence Between Two Techniques

NCT01832025
View directory record Official record
Conditions
Edentulous Posterior Maxilla
Interventions
internal maxillary sinus floor elevation technique, external maxillary sinus floor elevation technique
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Ridge Augmentation Comparing a Block Allograft to a Demineralized Bone Matrix Allograft.

NCT02127112
View directory record Official record
Conditions
Alveolar Process Defect
Interventions
Block Allograft plus Matrix Allograft, Moldable Matrix Allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance of MicroTextured Dental Implants

NCT01821417
View directory record Official record
Conditions
Partially Edentulous Jaw
Interventions
Microtextured dental implant treatment, Dental implant treatment
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Study on OsseoSpeed™ Implants Replacing 2-5 Teeth in the Posterior Upper Jaw, Restored With Provisional Teeth Attached 6-7 Weeks Later

NCT00711113
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
2
States / cities
Iowa City, Iowa • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Results available

Success Rate of Immediately Loaded Implants With Platform Switched Design Placed in Anterior Part of Mandible and Restored With Fixed Prostheses

NCT00780273
View directory record Official record
Conditions
Edentulism
Interventions
Ankylos Implants, Biomet 3i Prevail Implants
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2014 · Synced Sep 14, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional Results available

A Clinical Study on Acuris™ - Conometric Concept for Single Tooth Restoration

NCT04063878
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Conometric Abutment and Conometric Final Cap
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fabrication of a Definitive Cad/Cam Titanium Abutment Prior to Guided Surgery: a Pilot Study.

NCT02218541
View directory record Official record
Conditions
Single Edentulous Space
Interventions
abutment margin 0.5 mm subgingival, abutment margin 1.5 mm subgingival
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Sep 14, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional

Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients

NCT05264545
View directory record Official record
Conditions
Partially Edentulous Maxilla or Mandible
Interventions
PrimeTaper EV
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
25 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
8
States / cities
Aurora, Colorado • Broomfield, Colorado • Oakbrook Terrace, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 14, 2026, 10:21 PM EDT
Terminated Not applicable Interventional

Evaluation of Treatment With Fixture Microthread™ in Patients Missing All Teeth in the Upper Jaw, When Using One-Stage Surgery

NCT00748397
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
Fixture MicroThread (Micro-Macro)
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 7, 2008 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper Jaw

NCT00820235
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™, NobelSpeedy™ Replace®, NanoTite™ Certain® PREVAIL®
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
3
States / cities
Iowa City, Iowa • Chapel Hill, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2020 · Synced Sep 14, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Study on OsseoSpeed™ Implants in Patients Missing 2-5 Teeth in the Posterior Lower Jaw, Restored With Permanent Teeth Attached 6-7 Weeks Later

NCT00711425
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
2
States / cities
Columbus, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 8, 2013 · Synced Sep 14, 2026, 10:21 PM EDT