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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Edentulous Mouth Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Two Dissolvable Therapeutics Under Removable Partial Dentures

NCT05441527
View directory record Official record
Conditions
Edentulous Jaw, Edentulous Mouth
Interventions
MI Paste, then, Biotene Dry Mouth Gel, Biotene Dry Mouth Gel, then, MI Paste
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of OSSIX-Plus Resorbable Collagen Membranes for Alveolar Ridge Preservation Following Exodontia

NCT00639860
View directory record Official record
Conditions
Alveolar Bone Loss, Loss of Teeth Due to Extraction, Edentulous Alveolar Ridge
Interventions
OSSIX-Plus
Device
Lead sponsor
William Giannobile
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Jul 23, 2026, 6:08 AM EDT
Not yet recruiting Not applicable Interventional

Clinical Outcomes of 3D Printed and Milled Complete Dentures

NCT07586774
View directory record Official record
Conditions
Edentulous Mouth, Edentulous Jaw
Interventions
Lucitone Digital Print, Lucitone Digital Fit
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Results available

Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 Diabetes

NCT01142297
View directory record Official record
Conditions
Partially Edentulous Mandible, Type 2 Diabetes
Interventions
dental implant and modified dental implant
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Results available

Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior Jaw

NCT00545818
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™ length 6 mm, OsseoSpeed™ length 11 mm
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years to 70 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
2
States / cities
Los Angeles, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Jul 23, 2026, 6:08 AM EDT
Withdrawn No phase listed Observational

A Descriptive, Prospective Clinical Study to Evaluate Full Dentures Fabricated by Additive Manufacturing

NCT03997604
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Full Dentures created by additive manufacturing
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Northglenn, Colorado • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 16, 2022 · Synced Jul 23, 2026, 6:08 AM EDT
Terminated No phase listed Observational

A Full-Arch Implant- Supported Prosthesis in the Upper and/or Lower Jaw-USA

NCT03655990
View directory record Official record
Conditions
Missing Teeth
Interventions
Treatment with the JUVORA™ Dental Disc
Device
Lead sponsor
Juvora Ltd.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Jul 23, 2026, 6:08 AM EDT
Recruiting Phase 4 Interventional

Clinical Performance of Nobel N1 System

NCT07280260
View directory record Official record
Conditions
Tooth Loss, Dental Implant
Interventions
Nobel N1 implant
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Jul 23, 2026, 6:08 AM EDT
Active, not recruiting Not applicable Interventional

Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth Restorations

NCT05315414
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
PrimeTaper EV implant
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 23, 2026, 6:08 AM EDT
Terminated No phase listed Observational

Novel Technique for Face Mask Ventilation

NCT01946464
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 25, 2016 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The TREFOIL Concept 5 Year Clinical Investigation

NCT02940353
View directory record Official record
Conditions
Edentulous or Failing Dentition Mandible
Interventions
TREFOIL concept
Device
Lead sponsor
Nobel Biocare
Industry
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 23, 2026, 6:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Observational Clinical Study of the T3 Dental Implant System

NCT05062863
View directory record Official record
Conditions
Edentulous Jaw
Interventions
T3 dental implant system
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
Gainesville, Florida • Neptune City, New Jersey • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 23, 2026, 6:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Longitudinal Efficacy of Dental Implants in Anterior Areas

NCT00641277
View directory record Official record
Conditions
Edentulous
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Results available

Study to Compare Marginal Bone Loss Around Implants From Two Dental Implant Systems.

NCT00746187
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
ASTRA TECH Implant System; Fixture ST: Ø 4.5 cm in lengths of 9, 11 and 13 mm., 3i Osseotite® implant: Ø 4.0 in lengths of 8.5, 10, 11.5 and 13 mm
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
2
States / cities
New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Esthetic, Clinical and Radiographic Outcomes of Immediately Placed Implants (Type 1) and Early Placed Implants (Type 2)

NCT01623739
View directory record Official record
Conditions
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Interventions
Placement of a dental implant
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Results available

Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading

NCT00748241
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Astra Tech Fixture ST
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional

A Clinical Study of the Eztetic Dental Implant System

NCT03917927
View directory record Official record
Conditions
Edentulous Jaw
Interventions
Eztetic dental implant
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Jul 23, 2026, 6:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects

NCT00001211
View directory record Official record
Conditions
Ectodermal Dysplasia, Jaw, Edentulous
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1986 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance of MicroTextured Dental Implants

NCT01821417
View directory record Official record
Conditions
Partially Edentulous Jaw
Interventions
Microtextured dental implant treatment, Dental implant treatment
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate Bone and Gum Dimension Changes Around Dental Implants Placed in Different Positions in Bone.

NCT01759537
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Ankylos dental endosseous implants-Sub-crestal, Ankylos dental endosseous implants-Epi-crestal
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Incidence Between Two Techniques

NCT01832025
View directory record Official record
Conditions
Edentulous Posterior Maxilla
Interventions
internal maxillary sinus floor elevation technique, external maxillary sinus floor elevation technique
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implant Placement With Simultaneous Gum Grafting

NCT01431144
View directory record Official record
Conditions
Edentulous
Interventions
connective tissue autograft, connective tissue allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jul 23, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fabrication of a Definitive Cad/Cam Titanium Abutment Prior to Guided Surgery: a Pilot Study.

NCT02218541
View directory record Official record
Conditions
Single Edentulous Space
Interventions
abutment margin 0.5 mm subgingival, abutment margin 1.5 mm subgingival
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Jul 23, 2026, 6:08 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Prospective, Comparative Assessment of Alveolar Bone Augmentation Using GUIDOR® Membrane in the Bound Edentulous Space

NCT02387008
View directory record Official record
Conditions
Bone Regeneration
Interventions
GUIDOR® membrane with FDBA, GUIDOR® membrane, Bio-Gide® membrane with FDBA
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jul 23, 2026, 6:08 AM EDT