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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Embryonic Development Clear all
Completed Not applicable Interventional

Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection

NCT00114725
View directory record Official record
Conditions
Infertility, Infertility, Male
Interventions
Laser-assisted intracytoplasmic sperm injection
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 27, 2026, 5:15 AM EDT
Completed Not applicable Interventional

in Vitro Fertilization (IVF) Media Protein and Live Birth Rates

NCT00708383
View directory record Official record
Conditions
Infertility, Pregnancy Outcome, Live Birth, In Vitro Fertilization
Interventions
10% SSS embryo culture medium protein supplementation, 0.5% HSA embryo culture medium protein supplementation
Other
Lead sponsor
Texas Health Resources
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
2
States / cities
Dallas, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2008 · Synced Jun 27, 2026, 5:15 AM EDT
Completed Phase 2 Interventional

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

NCT01854294
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
GM604, Placebo comparator
Drug
Lead sponsor
Genervon Biopharmaceuticals, LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Jun 27, 2026, 5:15 AM EDT
Active, not recruiting Not applicable Interventional

HELIOS: Human Embryo Illumination to Enhance Development

NCT07311928
View directory record Official record
Conditions
IVF Outcomes
Interventions
Photobiomodulation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jun 27, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlation Between Oocyte and Embryo Mechanical Properties on Embryo Development and Clinical Pregnancy After In Vitro Fertilization

NCT02530892
View directory record Official record
Conditions
Infertility, Pregnancy, Multiple
Interventions
EmbryoHug
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Jun 27, 2026, 5:15 AM EDT
Completed No phase listed Observational

Molecular Analysis of Microphthalmia/Anophthalmia

NCT00011843
View directory record Official record
Conditions
Anophthalmos
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 27, 2026, 5:15 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Impact of the Timing of Trigger on IVF Success

NCT02990949
View directory record Official record
Conditions
Fertilization in Vitro, Infertility, Embryonic Development
Interventions
Timing of trigger
Other
Lead sponsor
Colorado Center for Reproductive Medicine
Other
Eligibility
26 Years to 44 Years · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Lone Tree, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development

NCT06990841
View directory record Official record
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos

NCT04109846
View directory record Official record
Conditions
Aneuploidy, Mosaicism, Pregnancy Outcome
Interventions
Non-euploid embryo transfer, Euploid Transfer
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2039
U.S. locations
1
States / cities
Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jun 27, 2026, 5:15 AM EDT
Terminated Phase 1 Interventional

Safety and Efficacy of MAK683 in Adult Patients With Advanced Malignancies

NCT02900651
View directory record Official record
Conditions
Diffuse Large B-cell Lymphoma
Interventions
MAK683
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
3
States / cities
San Francisco, California • Santa Monica, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jun 27, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oocyte Cryopreservation Comparing Fresh and Vitrified Sibling Oocytes

NCT00986687
View directory record Official record
Conditions
Infertility
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 37 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Jun 27, 2026, 5:15 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Evaluation of Donated Human Embryos Following in Vitro Fertilization

NCT01219361
View directory record Official record
Conditions
Validation of Laboratory Techniques, Validation of Laboratory Methods, Assessment of Laboratory Staff Proficiency
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2026
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Jun 27, 2026, 5:15 AM EDT
Completed Phase 1 Interventional

In Vitro Human Embryo Culture System

NCT00985218
View directory record Official record
Conditions
Infertility
Interventions
SMART System, Culture dish
Device
Lead sponsor
Incept BioSystems, Inc.
Industry
Eligibility
21 Years to 35 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
4
States / cities
San Francisco, California • Clearwater, Florida • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2010 · Synced Jun 27, 2026, 5:15 AM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF

NCT01202643
View directory record Official record
Conditions
Infertility, Female
Interventions
G-CSF, Saline
Drug
Lead sponsor
Center for Human Reproduction
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Phase 3 Interventional

Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.

NCT07216742
View directory record Official record
Conditions
Infertility (IVF Patients)
Interventions
hMG subcutaneous injection, Placebo
Drug
Lead sponsor
Granata Bio Corporation
Industry
Eligibility
18 Years to 42 Years · Female only
Enrollment
659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
16
States / cities
Encino, California • Norwalk, Connecticut • Newark, Delaware + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jun 27, 2026, 5:15 AM EDT
Completed No phase listed Observational

Human MATER and Idiopathic Infertility

NCT00361816
View directory record Official record
Conditions
Infertility
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques

NCT07175571
View directory record Official record
Conditions
Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
Interventions
Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jun 27, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oocyte Cryopreservation: Slow Cooling Versus Vitrification Techniques on Oocyte Survival

NCT00602966
View directory record Official record
Conditions
Infertility
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 36 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 27, 2011 · Synced Jun 27, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Human Embryo Development Using Sequential and Single Media With Time-lapse Imaging

NCT01939626
View directory record Official record
Conditions
Infertility
Interventions
Single-step medium, Standard culture medium
Device
Lead sponsor
Vitrolife
Industry
Eligibility
21 Years to 40 Years · Female only
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
San Francisco, California • Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Jun 27, 2026, 5:15 AM EDT
Completed Not applicable Interventional

An Alternative Culture Medium to Better Support Preimplantation Embryo Development in Vitro

NCT02457481
View directory record Official record
Conditions
Infertility, Reproductive Techniques, Assisted
Interventions
Embryo Culture medium
Device
Lead sponsor
National Foundation for Fertility Research
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Lone Tree, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Jun 27, 2026, 5:15 AM EDT
Not listed Phase 1Phase 2 Interventional

Effect of Testosterone Treatment on Embryo Quality

NCT01662466
View directory record Official record
Conditions
Primary Ovarian Insufficiency, Female Infertility Due to Diminished Ovarian Reserve
Interventions
Testosterone cream (0.5mg per gram), DHEA, Placebo
Drug · Dietary Supplement
Lead sponsor
Center for Human Reproduction
Other
Eligibility
38 Years to 44 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
2
States / cities
New York, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 11, 2020 · Synced Jun 27, 2026, 5:15 AM EDT
Withdrawn No phase listed Observational

Molecular Markers of Human Sperm Function

NCT00767611
View directory record Official record
Conditions
Infertility, Reproduction, Reproductive Techniques, Assisted
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2012 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HELIOS Advanced: Human Oocyte Illumination to Enhance Development

NCT07425080
View directory record Official record
Conditions
IVF Outcomes
Interventions
Photobiomodulation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jun 27, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

NCT04149496
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
in vitro maturation of oocytes
Combination Product
Lead sponsor
Bruce Rose, MD
Other
Eligibility
18 Years to 38 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Jun 27, 2026, 5:15 AM EDT