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ClinicalTrials.gov public records Last synced Oct 18, 2026, 10:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 1,406 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Emergency Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ketamine for Acute Migraine in the Emergency Department

NCT02697071
View directory record Official record
Conditions
Headache
Interventions
Ketamine, Normal Saline
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury

NCT01270659
View directory record Official record
Conditions
Pain
Interventions
Fentanyl, oxycodone/acetaminophen
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Phase 1 Interventional

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

NCT01740492
View directory record Official record
Conditions
Pain
Interventions
Ketamine 0.15mg/kg, Ketamine 0.3mg/kg, Placebo
Drug · Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Phase 3 Interventional Results available

Intranasal Fentanyl as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage

NCT03872700
View directory record Official record
Conditions
Abscess
Interventions
Intranasal fentanyl, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Not applicable Interventional

Virtual Reality as an Adjuvant Therapy for Sickle Cell Vaso-Occlusive Crisis in the Pediatric Emergency Department

NCT05864092
View directory record Official record
Conditions
Sickle Cell Crisis
Interventions
Virtual Reality Goggles
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
6 Years to 21 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 18, 2026, 10:01 AM EDT
Completed No phase listed Observational

Improving Signout Accuracy and Information Delivery in the Emergency Department

NCT01859286
View directory record Official record
Conditions
Medical Errors Related to Emergency Department Sign Out
Interventions
standardized sign out process
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2013 · Synced Oct 18, 2026, 10:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Wisconsin Evaluation of Emergency Department Care Coordination

NCT04550169
View directory record Official record
Conditions
Emergency Department Visit
Interventions
Intensive Care Coordination
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 64 Years
Enrollment
3,405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
4
States / cities
Appleton, Wisconsin • Glendale, Wisconsin • Milwaukee, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 18, 2026, 10:01 AM EDT
No Longer Available No phase listed Expanded access

EPI-743 for Mitochondrial Respiratory Chain Diseases

NCT01370447
View directory record Official record
Conditions
Mitochondrial Diseases
Interventions
EPI-743
Drug
Lead sponsor
PTC Therapeutics
Industry
Eligibility
1 Year and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
16
States / cities
Los Angeles, California • Orange, California • Palo Alto, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Emergency Manuals During Interprofessional Crisis Management: Are There Unintended Consequences?

NCT03006549
View directory record Official record
Conditions
Safety Issues
Interventions
Emergency Manual (Crisis Checklist)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Not applicable Interventional

Closed Reduction of Distal Forearm Fractures by Pediatric Emergency Medicine Physicians: A Prospective Study

NCT01101607
View directory record Official record
Conditions
Pediatric Distal Forearm Fractures
Interventions
Distal Forearm Fracture Reduction
Procedure
Lead sponsor
InMotion Orthopaedic Research Center
Other
Eligibility
6 Months to 18 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 12, 2010 · Synced Oct 18, 2026, 10:01 AM EDT
Not listed Phase 2 Interventional

Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department

NCT03256487
View directory record Official record
Conditions
Pain
Interventions
Buprenorphine, Morphine Sulfate
Drug
Lead sponsor
Alameda Health System
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 18, 2026, 10:01 AM EDT
Recruiting Not applicable Interventional

Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum

NCT04162938
View directory record Official record
Conditions
Hepatitis C
Interventions
Patient-Centered Electronic App
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 18, 2026, 10:01 AM EDT
Recruiting Not applicable Interventional

Telehealth vs In-Person Evaluation of Addiction Treatment After Visiting the Emergency Department

NCT06961058
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
referral to telehealth treatment, referral to in person treatment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
El Centro, California • Sacramento, California • Sylmar, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 18, 2026, 10:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Safety, Tolerability, and Efficacy of ellaOne® (Ulipristal Acetate) for Emergency Contraception in Postmenarcheal Adolescent Girls and Women

NCT01107106
View directory record Official record
Conditions
Contraception
Interventions
ellaOne® (ulipristal acetate)
Drug
Lead sponsor
HRA Pharma
Industry
Eligibility
Female only
Enrollment
579 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
4
States / cities
Denver, Colorado • Lakewood, Colorado • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Oct 18, 2026, 10:01 AM EDT
Not listed No phase listed Observational

Cerebral Oximetry and NIRS in Cardiac Arrest Patients

NCT03769740
View directory record Official record
Conditions
Cardiac Death, Cardiac Arrest, Emergencies
Interventions
Cerebral Oximetry
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
2
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Oct 18, 2026, 10:01 AM EDT
Terminated Not applicable Interventional Results available

Breath-Actuated Nebulizer Versus Conventional Continuous-Output Nebulizer in Pediatric Asthma Patients

NCT01045174
View directory record Official record
Conditions
Asthma
Interventions
Nebulizer (breath-actuated versus conventional continuous-output)
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
1 Year to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 18, 2026, 10:01 AM EDT
Completed No phase listed Observational

Development of a Risk Prediction Screening Tool for Opioid-Prescription Injury (STOP Injury) in Older Adults Initiated on Opioids From the Emergency Department

NCT03836235
View directory record Official record
Conditions
Opioid Use
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 120 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 18, 2026, 10:01 AM EDT
Completed Not applicable Interventional Results available

Intraosseous Versus Intravenous Vascular Access During Cardiac Arrest

NCT01119807
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Intravenous access during OHCA, Humeral IO insertion, TIbial IO insertion
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2022 · Synced Oct 18, 2026, 10:01 AM EDT
Completed No phase listed Observational

Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19

NCT04379544
View directory record Official record
Conditions
Coronavirus, Respiratory Failure
Interventions
Observation only
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 18, 2026, 10:01 AM EDT
Not listed Not applicable Interventional

Biphasic Ventilation Airway Management Clinical Trial

NCT03042598
View directory record Official record
Conditions
Intubation
Interventions
Biphasic Cuirass Ventilation
Device
Lead sponsor
University Medical Center of Southern Nevada
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 18, 2026, 10:01 AM EDT
Enrolling by invitation Phase 4 Interventional

Irrisept in Emergency General Surgery Patients

NCT07048899
View directory record Official record
Conditions
Emergency Surgery, Surgical Site Infections
Interventions
Chlorhexidine, Normal Saline
Drug
Lead sponsor
The University of Texas Health Science Center at Tyler
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 18, 2026, 10:01 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Polk COVID-19 and Flu Response

NCT04682132
View directory record Official record
Conditions
Covid19
Interventions
COVID-19 antigen and antibody tests, and influenza rapid test
Diagnostic Test
Lead sponsor
Polk County Fire Rescue
Government
Eligibility
18 Years and older
Enrollment
686 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bartow, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 18, 2026, 10:01 AM EDT
Not listed No phase listed Observational

A Multi-center, Non-interventional Prospective Clinical Trial to Evaluate the Safety and Effectiveness of CVA-FLOW

NCT06101004
View directory record Official record
Conditions
Stroke
Interventions
CVA-Flow
Device
Lead sponsor
Cvaid Medical
Industry
Eligibility
21 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 18, 2026, 10:01 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department

NCT07667621
View directory record Official record
Conditions
Migraine, Migraine Disease, Migraine in Adults, Migraine Headache, Acute Migraine, Migraine Without Aura, Migraine With Aura
Interventions
Rimegepant, Zavegepant
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 18, 2026, 10:01 AM EDT