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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Emergency Department Patients Clear all
Completed Not applicable Interventional

Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients

NCT06117605
View directory record Official record
Conditions
Sepsis, Electronic Health Records, Clinical Decision Support Systems
Interventions
Nurse SIRS alert, Prescribing clinician SIRS alert
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
25,668 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis

NCT00762424
View directory record Official record
Conditions
Kidney Stone
Interventions
Flowmax, placebo
Drug
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Sep 28, 2026, 11:30 AM EDT
Withdrawn Phase 2 Interventional

Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain

NCT02137525
View directory record Official record
Conditions
Acute Pain
Interventions
Morphine 6 mg, Fentanyl 100 µg, Fentanyl 200 µg, Fentanyl 400 µg, Placebo Sublingual Spray, Intravenous Placebo
Drug
Lead sponsor
INSYS Therapeutics Inc
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
15
States / cities
Phoenix, Arizona • Sylmar, California • Kansas City, Kansas + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 4, 2017 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Ultrasound Guidance for Intravenous Cannulation in Emergency Department Patients.

NCT00692549
View directory record Official record
Conditions
Difficult IV Access
Interventions
ultrasound
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Sep 28, 2026, 11:30 AM EDT
Not listed Phase 2 Interventional

Offering Influenza and Pneumococcal Vaccine to Patients Being Evaluated in the Emergency Department

NCT00380679
View directory record Official record
Conditions
High Risk for Serious Influenza, High Risk for Pneumonia
Interventions
Influenza vaccination, Pneumococcal polysaccharide vaccination
Biological
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 25, 2006 · Synced Sep 28, 2026, 11:30 AM EDT
Withdrawn Phase 2 Interventional

Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)

NCT00711698
View directory record Official record
Conditions
Sickle Cell Disease, Vaso-occlusive Crisis
Interventions
Patient controlled analgesia, nurse-administered intermittent IV bolus opioid therapy (NAIBOD)
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Pre-Discharge Bundle for Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease to Reduce Readmissions

NCT02135744
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions
Bundle tool
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
40 Years to 99 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 28, 2026, 11:30 AM EDT
Not yet recruiting Not applicable Interventional

Advancing Scalable Alcohol Brief Interventions in the ED: A Trial of Conversational AI With Digital Reinforcements

NCT07661563
View directory record Official record
Conditions
Alcohol Misuse
Interventions
MICA, TRAC
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Facilitating Access to Specialty Treatment

NCT05741411
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
Interventions
RPM-assisted specialist access
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 18 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients

NCT00116584
View directory record Official record
Conditions
Bronchiolitis
Interventions
heliox, oxygen
Drug
Lead sponsor
University of Louisville
Other
Eligibility
2 Months to 12 Months
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Prospective Feasibility Trial of AccuCath 2.25" Blood Control (BC) Placed in Difficult Access Patients in the Emergency Department

NCT02449798
View directory record Official record
Conditions
Vascular Access Complication
Interventions
AccuCath 2.25" BC Intravascular Catheter
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 28, 2026, 11:30 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients

NCT07670507
View directory record Official record
Conditions
Pain Management
Interventions
oral ketamine, oxycodone
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Completed No phase listed Observational

Capacity to Consent in Acutely Intoxicated Emergency Department Patients

NCT02885532
View directory record Official record
Conditions
Informed Consent
Interventions
University of California, San Diego Brief Assessment of Capacity to Consent Tool
Other
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Sep 28, 2026, 11:30 AM EDT
Terminated Not applicable Interventional

Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.

NCT02470728
View directory record Official record
Conditions
Pain, Acute Pain, Postoperative Pain
Interventions
New Clinical Pathway
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Orange, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Video Assisted Informed Consent for Lortab to Improve Patient Satisfaction and Knowledge

NCT01374295
View directory record Official record
Conditions
Non-critical Emergency Room Patients Receiving Lortab Medication or Prescription During Their Emergency Room Visit
Interventions
video, standard education
Other
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2014 · Synced Sep 28, 2026, 11:30 AM EDT
Terminated Not applicable Interventional

Medication Histories Conducted by Nurses (RNs), Pharmacy Techs (CPhTs) & Pharmacists (RPhs)

NCT01065675
View directory record Official record
Conditions
Medication Reconciliation, Emergency Department
Interventions
Medication reconciliation completed by a RN, CPhT, or RPh
Other
Lead sponsor
Wesley Medical Center
Other
Eligibility
Not listed
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2012 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Patient-Directed Antimicrobial Duration in Acute Uncomplicated Pyelonephritis

NCT06127160
View directory record Official record
Conditions
Pyelonephritis Acute
Interventions
Cephalexin, Cephalexin or placebo
Drug
Lead sponsor
Brett A Faine
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Sylmar, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Completed No phase listed Observational

Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department

NCT05544903
View directory record Official record
Conditions
Sepsis
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Engaging Patients With Mental Disorders From the ED in Outpatient Care

NCT02989805
View directory record Official record
Conditions
Mental Disorder
Interventions
Care Management
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2020 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments

NCT02586896
View directory record Official record
Conditions
Opioid Dependence
Interventions
Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Intraosseous Access in the Emergency Department for Patients With Failed Attempts at Intravenous Access: A Randomized Trial Examining Resource Utilization and Patient Satisfaction

NCT01676350
View directory record Official record
Conditions
Difficult Peripheral IV Access
Interventions
IO access using EZ-IO®
Procedure
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Phase 4 Interventional Results available

Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease

NCT02222246
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Hydromorphone (Standardized, weight-based dosing), Morphine Sulfate (Standardized, weight-based dosing), Hydromorphone (Patient Specific dosing), Morphine Sulfate (Patient Specific dosing)
Drug
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
New York, New York • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2017 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Effect of Emergency Department Bedside Compression Ultrasonography on Door-to-Disposition Time in Patients Suspicious for Lower Extremity Deep Venous Thrombosis

NCT05682040
View directory record Official record
Conditions
Lower Extremity Deep Vein Thrombosis
Interventions
Bedside Compression Ultrasonography
Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Wyandotte, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 28, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Promoting Cervical Cancer Screening for Emergency Department Patients

NCT03483610
View directory record Official record
Conditions
Cervical Cancer
Interventions
Provider Referral, Text Messaging
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 28, 2026, 11:30 AM EDT