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ClinicalTrials.gov public records Last synced Nov 10, 2026, 4:10 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 1,393 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Emergency Room Clear all

Conditions: Psychiatric Issue
Interventions: level of agitation; Behavioral
Lead sponsor: Leslie Zun, MD; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sepsis Syndrome, Sepsis, Severe Sepsis, Septic Shock, Infection
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 1,304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Brooklyn, New York • New York, New York

Conditions: Melena, Gastrointestinal Hemorrhage
Interventions: Early Video Capsule Endoscopy; Device
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Headache
Interventions: Ketamine, Normal Saline; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Agitation
Interventions: Quetiapine, Haloperidol, Lorazepam, Cogentin; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 60 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Vaso-Occlusive Pain Episode in Sickle Cell Disease, Sickle Cell Disease (SCD)
Interventions: Standardized Low-dose bolus IV Ketamine within 30 minutes of arrival and every 1 hour as needed for max of 3 doses., Standard Care (in control arm); Drug · Other
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 2 Years to 21 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Opioid-use Disorder, Mental Disorder, Opioid Medication Assisted Treatment
Interventions: Bridge Clinic; Other
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Diabetic Ketoacidosis
Interventions: glargine, saline; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 6 Years to 18 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acute Otitis Media, Acute Otitis Externa
Interventions: Smartphone otoscope, Conventional otoscope; Device
Lead sponsor: Emory University; Other
Eligibility: Not listed
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Chest Pain
Interventions: autoRIC® device; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 100 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Housing Problems, Drug Use, Alcohol; Use, Problem
Interventions: Referral to homelessness prevention services, Substance use services, Follow-up; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Use Disorder
Interventions: Contingency Management, Usual care as prescribed by the ED physicians; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Sepsis
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Urinary Tract Infections, Urosepsis
Interventions: urine culture and susceptibility testing; Other
Lead sponsor: Olive View-UCLA Education & Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 801 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Sylmar, California

Conditions: Obesity, Contraception
Interventions: UPA-ECx1, UPA-ECx2; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hospital Readmission
Interventions: CHS Transition Services; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 1,876 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Acute Pain
Interventions: Not listed
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 3,630 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: COPD Exacerbation
Interventions: Revefenacin, formoterol fumarate, Placebo (Sterile Normal Saline), Albuterol sulfate, Ipratropium Bromide; Drug · Other
Lead sponsor: University of Tennessee Graduate School of Medicine; Other
Eligibility: 40 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Nausea
Interventions: Ondansetron, Metoclopramide, Promethazine, Normal Saline; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Angioedema
Interventions: Not listed
Lead sponsor: Methodist Health System; Other
Eligibility: 18 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Migraine
Interventions: metoclopramide, Dexamethasone, methylprednisolone acetate; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: The Bronx, New York

Conditions: Forearm Fracture, Ultrasound
Interventions: Ultrasound - guided fracture reduction, Standard of care fracture reduction; Radiation · Procedure
Lead sponsor: Montefiore Medical Center; Other
Eligibility: Up to 21 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Pain, Fracture, Sprain
Interventions: Fentanyl, Lansoprazole, Oxycodone; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Behavior, Child, Anxiety
Interventions: Virtual Reality Game; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 6 Years to 17 Years
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

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Self Reported Level of Agitation of Patients Presenting to an Emergency Department

Mitochondrial DNA as a Biomarker of Sepsis Severity

Comparing Early Capsule Deployment to Current Standard of Care for Management of Gastrointestinal Bleeding

Ketamine for Acute Migraine in the Emergency Department

A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room

Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis

Start Treatment and Recovery for Opioid Use Disorder

Use of Insulin Glargine to Treat Diabetic Ketoacidosis

Pediatric Emergency Department Smartphone Otoscope Study (PED-Oto)

A Study of the Feasibility of Prehospital Remote Ischemic Conditioning

ED-Home Pilot Study

Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department

Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department

Prevalence of Antimicrobial-resistant Pathogens in Patients Admitted for UTIs

Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA

Aiming to Improve Readmissions Through InteGrated Hospital Transitions

Measuring Changes in Acute Pain in the Emergency Department Using Patient Reported Scales

Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)

Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED

Evaluation of Tranexamic Acid for Angiotensin-converting Enzyme Inhibitor-induced Angioedema in the Emergency Department

Corticosteroids for Acute Migraine in the Emergency Department

Trial of Ultrasound Guidance for Reduction of Pediatric Forearm Fractures

Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department