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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 985–1008 of 1,393 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Emergency Room Clear all

Conditions: Atrial Fibrillation and Flutter
Interventions: Comprehensive ED AF management tool; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 4,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 16
States / cities: Antioch, California • Fremont, California • Manteca, California + 12 more

Conditions: Alcohol Use Disorder
Interventions: Emergency Department Initiated Oral Naltrexone; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Music Therapy, Patient Satisfaction
Interventions: Live preferential music; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 1,107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Endotracheal Tube Cuff Pressure Pediatric Emergency
Interventions: Cuffed ETT; Device
Lead sponsor: Edward Ferenczy; Other
Eligibility: Not listed
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Type 2 Diabetes Mellitus
Interventions: Antihyperglycemic medication guideline for management of uncontrolled hyperglycemia presenting to the ED using metformin, sulfonylurea and/or insulin, Diabetes survival skills self-management education; Drug · Behavioral
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Acute Vaso Occlusive Crisis (VOC)
Interventions: L-citrulline, D5 1/2NS; Drug · Other
Lead sponsor: Asklepion Pharmaceuticals, LLC; Industry
Eligibility: 6 Years to 21 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Jackson, Mississippi

Conditions: Improving Informed Consent Process
Interventions: Multimedia Presentation for Ketamine sedation; Other
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 1 Year to 18 Years
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: History Taking, Artificial Intelligence (AI)
Interventions: MINERVA AI Chatbot; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Vital Sign Evaluation
Interventions: SmartSpectra Vital Signs Monitor measurement; Device
Lead sponsor: Presage Technologies, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Headache, Migraine
Interventions: Metoclopramide, Haloperidol, Normal Saline, Diphenhydramine; Drug · Other
Lead sponsor: OhioHealth; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Pain, Acute
Interventions: Oral Ibuprofen; Drug
Lead sponsor: Antonios Likourezos; Other
Eligibility: 18 Years to 120 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Headache
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 477 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Acute Back Pain
Interventions: Battlefield auricular acupressure, Sham; Procedure
Lead sponsor: Hackensack Meridian Health; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Hackensack, New Jersey

Conditions: Hunger, Child Nutrition Disorders
Interventions: Food Insecurity Screening Tablet, Food Insecurity Screening Verbal; Other
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 18 Years and older
Enrollment: 1,818 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sepsis, Adult Disease, Severe Sepsis, Emergency Department
Interventions: CBC-DIFF Monocyte Volume Width Distribution (MDW); Diagnostic Test
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 1,139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Severe Hypertension, Hypertension
Interventions: Emergency Department-Initiated Team-Based Care, Usual Care; Other
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 85 Years
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 5
States / cities: Brownstown, Michigan • Dearborn, Michigan • Detroit, Michigan + 1 more

Conditions: Severe Sepsis, Septic Shock
Interventions: Modified EGDT, Standard EGDT; Procedure
Lead sponsor: National Institute of General Medical Sciences (NIGMS); NIH
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Boston, Massachusetts • Camden, New Jersey • Charlotte, North Carolina

Conditions: Traumatic Lumbar Puncture
Interventions: Bedside Ultrasound-Assisted Site Marking, Mindray M7 Ultrasound, Routine lumbar puncture; Procedure · Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Up to 6 Months
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cardiac Arrest, Out-Of-Hospital, Hypotension
Interventions: Not listed
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 1,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 8
States / cities: Denver, Colorado • Worcester, Massachusetts • Lebanon, New Hampshire + 5 more

Conditions: Housing Problems, Drug Use, Alcohol; Use, Problem
Interventions: Referral to homelessness prevention services, Substance use services, Follow-up; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Syncope
Interventions: Emergency Department Observation Protocol, Unstructured, inpatient evaluation; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 4
States / cities: Los Angeles, California • Boston, Massachusetts • Royal Oaks, Michigan + 1 more

Conditions: Heart Failure
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Opioid Overdose Prevention, HIV Prevention and Care, Harm Reduction
Interventions: PROTECT-ED Care Coordination; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sepsis
Interventions: Epic Sepsis Model Version - 1, Epic Sepsis Model Version - 2, Emory Sepsis Model; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 7
States / cities: Atlanta, Georgia • Decatur, Georgia • Johns Creek, Georgia + 1 more

Search by objective public record fields.

Clinical Decision Support for Atrial Fibrillation and Flutter

ED Initiated Oral Naltrexone for AUD

Music in the Emergency Department (ED): Phase II

Endotracheal Tube (ETT) Cuff Pressure Study in the Emergency Department (ED)

Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC)

L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)

Use of a Multimedia Presentation for Informed Consent

Safety, Feasibility, and Acceptability of the MINERVA Voice Conversational Agent for Emergency Department History-Taking

Clinical Validation of Non-Contact Vital Signs

Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department

Adult Oral Ibuprofen Study for ED Pain Patients

Prospective ED Headache Cohort Study

Battlefield Acupressure for Acute Back Pain Management in the Emergency Department

Food for Thought: Food Insecurity Screening in the Emergency Department

Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University

Emergency Department-Initiated Team-Based Care for Severe Hypertension

Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation

The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps

Cardiac Arrest - Ultrasound Detection of Occult Perfusion

ED-Home Pilot Study

Evaluating an Emergency Department Observation Syncope Protocol for Older Adults

Identifying Diuretic Resistance in Patients With Acute Heart Failure

Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition From the Emergency Department

Comparison of Sepsis Prediction Algorithms