Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:20 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 570 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Emotional Depression Clear all

Conditions: Depressive Symptoms, Self-Appraisal
Interventions: Single Session Interventions; Behavioral
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 1,800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Depression, Anxiety, Cognitive Training, Emotion Training, Emotion Regulation
Interventions: Computerized neurobehavioral intervention; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Palo Alto, California • Stanford, California

Conditions: Affect, Bereavement, Emotions, Depressive Symptoms, Grief
Interventions: Cognitive Emotion Regulation Training; Behavioral
Lead sponsor: Bryan Denny; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Symptoms of Depression and Anxiety, Perceived Stress
Interventions: AI enabled wellness chatbot, Penn Digital Wellness Resources; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression, Anxiety, Physical Activity, Time in Nature, Self-Efficacy, Feasibility Pilot Study
Interventions: Walk-and-talk therapy; Behavioral
Lead sponsor: Kansas State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Manhattan, Kansas

Conditions: Depressive Symptoms, Heart Diseases
Interventions: Online cognitive behavioral therapy; Behavioral
Lead sponsor: Debra Moser; Other
Eligibility: 21 Years to 110 Years
Enrollment: 444 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Depression
Interventions: dCBI, Treatment as Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 16 Years to 22 Years
Enrollment: 185 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: San Diego, California • Boston, Massachusetts • Pittsburgh, Pennsylvania

Conditions: Depression
Interventions: Men's Healing Pathways; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Nurse Delivered Counseling, Emotional Distress
Interventions: RCT Treatment -Listening Visits delivered by NICU nurse in person, RCT Control Usual mental health care delivered by NICU social workers, Open trial: Listening Visits delivered by a NICU nurse via zoom; Behavioral
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older · Female only
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: IVF, In Vitro Fertilization, Quality of Life (QOL), Anxiety, Depression and Anxiety Symptom, Assisted Reproduction Technologies, Yoga, Mental Health
Interventions: Yoga; Behavioral
Lead sponsor: Villanova University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Villanova, Pennsylvania

Conditions: Severe Depression, Moderate Depression, Ketamine, Midazolam, Peripheral Nervous System Agents, Central Nervous System Agents, Neurotransmitter Agents, Physiologic Effects of Drugs, Sensory System Agents, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Depressive Symptom, Hypnotics and Sedatives, Anti-anxiety Agents, Tranquilizing Agents, Psychotropic Drugs, Anesthetics Agent
Interventions: nebulized ketamine, nebulized midazolam; Drug
Lead sponsor: Theresa Jacob, PhD, MPH; Other
Eligibility: 18 Years to 88 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Depression, Anxiety
Interventions: Lumen Treatment; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Major Depression
Interventions: Escitalopram; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Depression
Interventions: Rejection and Acceptance Feedback; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 13 Years to 17 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Depressive Disorder, Major
Interventions: No intervention; Other
Lead sponsor: Stanford University; Other
Eligibility: 9 Years to 15 Years · Female only
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2011
U.S. locations: 2
States / cities: Stanford, California

Conditions: Depressive Symptoms, Stress, Psychological
Interventions: mPEP, Bibliotherapy; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 40 Years and older
Enrollment: 184 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Malignant Neoplasm
Interventions: Internet-Based Intervention, Quality-of-Life Assessment, Questionnaire Administration; Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 15 Years to 34 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
Interventions: Coaching and Decision Aid; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Depression
Interventions: Exercise; Behavioral
Lead sponsor: Liberty University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 2
States / cities: Lynchburg, Virginia

Conditions: Involutional Depression, Anxiety Disorders
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 10 Years to 55 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2016
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hepatitis C, Depression
Interventions: Home-based walking program, Educational intervention; Behavioral · Other
Lead sponsor: Portland VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Depressive Symptoms
Interventions: Audio-based behavioral activation intervention, Audio-based self-monitoring intervention; Device
Lead sponsor: Penn State University; Other
Eligibility: 18 Years and older
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
Interventions: Clinician Supported PTSD Coach, Self Managed PTSD Coach; Behavioral
Lead sponsor: Florida International University; Other
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Depression, Anxiety, Substance Use, Stress, Psychological, Stress, Emotional, Alcohol Use, Unspecified, Drug Use, Covid19
Interventions: Mindfulness Based Cognitive Therapy for Resilience During COVID-19 plus CHAMindWell, Internet Cognitive Behavioral Therapy plus CHAMindWell, CHAMindWell; Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Search by objective public record fields.

Evaluating and Predicting Response to a Single Session Intervention for Self-Dislike

A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan

Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses

Elomia - Digital Mental Health and Well-Being

Promoting Active Therapy: Path to Wellness

Online Cognitive Behavioral Therapy for Depressive Symptoms in Rural Patients with Cardiac Disease

Study to Compare the Use of a Behavioral Health App Versus Care As Usual for 16-22 Year Olds with Depression

Depression in Men With Physical Disabilities

Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns

The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment

Nebulized Ketamine for the Treatment of Major Depressive Disorder

Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor (SPEAC) for Adults With Emotional Distress (Phase 1)

Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram

Teen Brain Online II: Understanding How Social Media Affects the Teen Brain

Mothers With a History of Depression and Their 10-14 Year Old Daughters

Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being

Talking Pictures Social Media Intervention in Reducing Depressive Symptoms and Improving Spiritual Well-Being and Quality of Life in Adolescent and Young Adult Cancer Patients

Equipping Patients Using Interventions for Pain and Depression

The Effects of Exercise on Depression Symptoms Using Levels of Neurotransmitters and EEG as Markers

MRI Study of Brain Activity and Risk for Depression in Adolescents

Efficacy of an Exercise Intervention to Decrease Depressive Symptoms in Veterans With Hepatitis C

Audio-based Mental Health Intervention Study

Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida

Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use