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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:59 AM EDT

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Showing 505–528 of 695 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Emotional Disorder Clear all
Completed Not applicable Interventional

Animal-Assisted Therapy in Pediatric Autism Spectrum Disorders

NCT06687850
View directory record Official record
Conditions
Pediatric Autism, Developmental Delay (Disorder), Behavioral Concerns
Interventions
animal assisted therapy
Behavioral
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
3 Years to 21 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 24, 2026, 4:59 AM EDT
Completed No phase listed Observational

Serotonin Function During Depression

NCT00033787
View directory record Official record
Conditions
Depression, Involutional, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Mental Health and Well-Being Via Awe Walks

NCT03550144
View directory record Official record
Conditions
Awe, Compassion, Anxiety
Interventions
Awe Walk, Control Walk
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 24, 2026, 4:59 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Talking Circle for Native American Youth Living Well (AYoLi)

NCT07746375
View directory record Official record
Conditions
Intervention Condition, Wait-List Control
Interventions
Talking Circle Intervention, Wait-List Control Group
Behavioral
Lead sponsor
Melessa Kelley
Other
Eligibility
10 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

StriveWeekly Online Mental Health Trial Post-pandemic

NCT04927845
View directory record Official record
Conditions
Anxiety, Depressive Symptoms, Stress, Emotional
Interventions
StriveWeekly
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
16 Years and older
Enrollment
538 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 24, 2026, 4:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Strengthening Community Mental Health

NCT06093737
View directory record Official record
Conditions
Mental Health, Emotional Wellbeing, Anxiety, Depression, Stress, Coping, Perceived Stress, Perceived Social Support
Interventions
COPE: Communities Organizing for Power through Empathy
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 24, 2026, 4:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Regulation of Emotions in People With Depression and Anhedonia

NCT00059579
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 24, 2026, 4:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

NCT05863520
View directory record Official record
Conditions
Autism Spectrum Disorder, Anxiety Disorders, Emotion Regulation
Interventions
Zones of Regulation, Facing Your Fears - School Based
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
7 Years to 15 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional

Unified Protocol for Adolescents (UP-A) Change Processes

NCT03102008
View directory record Official record
Conditions
Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem, Emotional Disorder
Interventions
Unified Protocol for Emotional Disorders in Adolescents (UP-A)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Oct 24, 2026, 4:59 AM EDT
Recruiting Not applicable Interventional

Music Listening for Mental Health Recovery After Stroke

NCT07127159
View directory record Official record
Conditions
Stroke
Interventions
Intentional Music Listening, Audiobook Listening
Behavioral
Lead sponsor
New York University
Other
Eligibility
50 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional

Positive Psychology to Improve Cardiac Health Behaviors

NCT01807442
View directory record Official record
Conditions
Acute Coronary Syndrome, Emotions, Patient Compliance
Interventions
Qualitative Interview and Adherence
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Phase 4 Interventional Results available

Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine

NCT00532480
View directory record Official record
Conditions
Major Depression
Interventions
Duloxetine
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Keppra on Thinking, Emotions, and Balance in Elderly Healthy Volunteers

NCT00221988
View directory record Official record
Conditions
Epilepsy
Interventions
Levetiracetam (Keppra)
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
65 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the CHIME Intervention for Improving Early Head Start/Head Start Educator Well-being

NCT05791825
View directory record Official record
Conditions
Health, Subjective, Work Related Stress, Compassion, Social Skills
Interventions
Cultivating Healthy Intentional Mindful Educators
Behavioral
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
Not listed
Enrollment
571 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional

Integrating Sleep, Nightmare and PTSD Treatments

NCT02236390
View directory record Official record
Conditions
Nightmares, PTSD
Interventions
Exposure, Relaxation, and Rescripting Therapy, Cognitive Processing Therapy - Cognitive
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 24, 2026, 4:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Human Stress Response in a Simulated ED Setting

NCT04317482
View directory record Official record
Conditions
Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence, Stress, Emotional
Interventions
Standard social stress task, Stressful experience in the ED
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transdermal Nicotine on Response Inhibition to Emotional Cues in Schizophrenia

NCT03838484
View directory record Official record
Conditions
Schizophrenia, Impulsive Behavior
Interventions
Nicotine Patch, 7 Mg/24 Hr, Placebo patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 24, 2026, 4:59 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood

NCT03003949
View directory record Official record
Conditions
Perimenopausal Disorder, Stress, Emotional
Interventions
Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release, Placebo Patch, Progesterone Capsule, Placebo Oral Capsule
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Phase 1 Interventional

Smoking Cessation for Depression and Anxiety Treatment

NCT02002858
View directory record Official record
Conditions
Smoking, Anxiety Disorders, Depression Disorders
Interventions
Nicotine Patch, Depression and Anxiety Smoking Cessation Treatment, Educational-Support Psychotherapy
Drug · Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional

Emotional Awareness and Expression Therapy for Chronic Pain and Opioid Use Disorder

NCT06865560
View directory record Official record
Conditions
Chronic Pain, Opioid Use Disorder
Interventions
Emotional Awareness and Expression Therapy (EAET)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Endogenous Opioid Activity and Affective State in Insulin Resistant Women

NCT02069379
View directory record Official record
Conditions
Depression, Insulin Resistance, Metabolic Syndrome
Interventions
Metformin, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of the Vermont Family Based Approach in Primary Care Pediatrics

NCT04412590
View directory record Official record
Conditions
Psychiatric Disorder
Interventions
Vermont Family Based Approach, Treatment as Usual
Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
3 Years to 15 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 24, 2026, 4:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System

NCT06997120
View directory record Official record
Conditions
Behavioral Health
Interventions
Bodhi AIM (intervention group), HIB (control group)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 24, 2026, 4:59 AM EDT
Completed Not applicable Interventional

Mother's Recorded Voice for Preterm Infants

NCT04559620
View directory record Official record
Conditions
Maternal Depressive Disorder Complicating Childbirth, Preterm Birth, Maternal Anxiety Disorder Complicating Childbirth
Interventions
Maternal voice
Other
Lead sponsor
AdventHealth
Other
Eligibility
Up to 3 Weeks
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 24, 2026, 4:59 AM EDT