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Showing 577–600 of 695 matching trials from the live ClinicalTrials.gov search.
Conditions
Emotional Distress, Anxiety, Depression
Interventions
Unified Protocol
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Depressive Disorder, Major
Interventions
LIFUP sonication to the amygdala
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Trial of a Voice-Based Generative AI Emotional Support Companion

NCT07860034
Conditions
Anxiety and Fear
Interventions
The intervention was the AI-based emotional support app., Psychoeducational Material
Device · Other
Lead sponsor
University of Cologne
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Stress Disorders, Post-Traumatic
Interventions
eBrainFit Platform
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Autism Spectrum Disorder
Interventions
The Emotion Awareness and Skills Enhancement Program, The Unified Protocol
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 30 Years
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tuscaloosa, Alabama • Pittsburgh, Pennsylvania
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Desensitization Therapy for insomnia (DT-I)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of CES on Emotional and Cellular Wellbeing

NCT03369418
Conditions
Anxiety, Depression
Interventions
Alpha-Stim Active, Alpha-Stim Inactive
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Parkinson Disease, Huntington Disease
Interventions
Group Drumming Music Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Pelvic Pain, Distress, Emotional
Interventions
Brief ACT with CPP Education Treatment
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Conditions
Autism Spectrum Disorder, Autism, Autistic Disorder, Asperger Syndrome
Interventions
TUNE In: Training to Understand and Navigate Emotions and Interactions
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

NCT07460622
Conditions
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
Interventions
Virtual Reality E-Cigarette Prevention Program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
1,251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Conditions
Child Safety, Coercion, Child Wellbeing, Adjustment, Parenting, Post Traumatic Stress Disorder, Mental Health, Child Maltreatment, Trauma, Emotional Regulation
Interventions
Online Parenting Program, No online parenting program
Behavioral · Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Conditions
Malignant Brain Tumor, Glioma, Coping Skills, Distress, Emotional
Interventions
Psychosocial intervention, Usual supportive care
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Emotional Disorder
Interventions
Safety Aid Reduction Treatment
Behavioral
Lead sponsor
Southeast Louisiana Veterans Health Care System
Federal
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Multiple Sclerosis
Interventions
Mindfulness Meditation, Computerized Cognitive Training
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 59 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Opiate Dependence
Interventions
Oxytocin
Drug
Lead sponsor
MacDonald, Kai, M.D.
Individual
Eligibility
18 Years and older · Male only
Timeline
Started 2013
U.S. locations
1
States / cities
San Diego, California
Conditions
Other Gastrointestinal Disorders, Cramp, Abdominal
Interventions
Funny/Amusing Video Clips, Horror/Scary Video Clips, Thrilling/Suspenseful Video Clips
Other
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Norfolk, Virginia
Conditions
Type 1 Diabetes
Interventions
ACT1VATE, DSME/S
Behavioral
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Diego, California
Conditions
Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders, Somatic Disorders, Obsessive Compulsive Disorders, Eating Disorders, Difficulties With Cognitive Emotion Regulation
Interventions
Cognitive Restructuring, rTMS, Sham rTMS
Behavioral · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Overweight Adolescents, Obese Adolescents
Interventions
Emotion regulation and self-monitoring to treat pediatric obesity, Psychoeducation
Behavioral · Other
Lead sponsor
Texas Tech University
Other
Eligibility
11 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Lubbock, Texas
Not listed Not applicable Interventional Accepts healthy volunteers

Well-being in Students and Teachers Study

NCT06203288
Conditions
Prosocial Behavior, Community Sense, Optimism, Anxiety, Social Competence, Self-Compassion, Stress, Psychological, Burnout, Professional, Efficacy, Self, Self Awareness
Interventions
Mindfulness-based social and emotional learning (MBSEL) program for educators, Mindfulness-based social and emotional learning (MBSEL) program for students
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
Not listed
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Frontotemporal Dementia, Frontotemporal Degeneration, Alzheimer's Disease, Social Behavior
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Emotional Response in Psychiatric and Control Participants

NCT03056781
Conditions
Schizophrenia, Emotions
Interventions
social interaction, food consumption
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Irvine, California