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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Emotional Dysfunction Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet-based Conversational Engagement Clinical Trial

NCT02871921
View directory record Official record
Conditions
Aging, Mild Cognitive Impairment
Interventions
Conversational Engagement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
75 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Jul 21, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)

NCT06133231
View directory record Official record
Conditions
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
Interventions
Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Music for the Mind Study

NCT06866327
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
Interventions
Piano lessons, Music Lessons
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

NCT04964726
View directory record Official record
Conditions
Emotional Dysfunction, Early Life Stress
Interventions
Real-time fMRI dyadic neurofeedback
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
14 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dairy Based Probiotic Intervention and Cognitive, Emotional, and Inflammatory Outcomes

NCT04643080
View directory record Official record
Conditions
Cognitive Decline, Cognitive Change, Inflammation, Emotions
Interventions
Yogurt
Other
Lead sponsor
University of Idaho
Other
Eligibility
50 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
4
States / cities
Boise, Idaho • Coeur d'Alene, Idaho • Pocatello, Idaho + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 21, 2026, 11:22 AM EDT
Active, not recruiting Not applicable Interventional

Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia

NCT04100057
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Desensitization Therapy for insomnia (DT-I)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Online Emotion Regulation Group Intervention

NCT03479606
View directory record Official record
Conditions
Traumatic Brain Injury, Executive Dysfunction, Emotion Dysfunction, Emotion Dysregulation
Interventions
Online Emotion Regulation Skills-training
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Jul 21, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

Brief Interventions for Coping with Distress

NCT05779761
View directory record Official record
Conditions
Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
Interventions
Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Jul 21, 2026, 11:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Focus Groups in Ethnically and Racially Diverse Families

NCT05930886
View directory record Official record
Conditions
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
Interventions
Focus Group
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts

NCT04901390
View directory record Official record
Conditions
Gastrointestinal Dysfunction, Physiological Stress, Cognition - Other
Interventions
Yogurt with B. lactis and added cane sugar
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
22 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Jul 21, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

Neurostimulation Versus Therapy for Problems With Emotions

NCT05712057
View directory record Official record
Conditions
Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders, OCD, Impulse Control Disorder, Eating Disorders, Emotional Dysfunction, Emotional Instability, Emotional Distress, Emotional Maladjustment, Emotional Impulsivity, Obsessive-Compulsive Disorder, Emotion Dysregulation, Borderline Personality Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring, Emotional Awareness Training
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 21, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

NCT07469384
View directory record Official record
Conditions
SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Interventions
transcranial direct current stimulation, Sham stimulation
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effects of Negative Emotions on Endothelial Function

NCT01909895
View directory record Official record
Conditions
Emotions, Endothelial Dysfunction
Interventions
Anger Induction, Depressed Mood Induction, Anxiety Induction, Neutral emotion task
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Jul 21, 2026, 11:22 AM EDT
Completed No phase listed Observational

Emotional Communication Disorders in Cerebellar Disease

NCT02106819
View directory record Official record
Conditions
Cerebellar Diseases
Interventions
Testing of emotional communication ability, magnetic resonance imaging (MRI) of the brain
Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Phase 1 Interventional

Online Emotional Regulation Group Treatment

NCT01730261
View directory record Official record
Conditions
Traumatic Brain Injury, Executive Dysfunction, Emotional Dysregulation
Interventions
Online Emotional Regulation Treatment
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Emotion Regulation Training Via Telehealth During the COVID-19 Pandemic

NCT04615416
View directory record Official record
Conditions
Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
Interventions
Emotion Regulation Training via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Jul 21, 2026, 11:22 AM EDT
Completed No phase listed Observational

Serotonin Function During Depression

NCT00033787
View directory record Official record
Conditions
Depression, Involutional, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Results available

CogT BEEM Study (a tDCS Study)

NCT04099524
View directory record Official record
Conditions
Mild Cognitive Impairment, Neuropsychiatric Syndrome
Interventions
tDCS
Device
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NECTAR Study: Nectar (Honey) Effects on Comfort, Thoughts, and Regularity

NCT04187950
View directory record Official record
Conditions
Gastrointestinal Dysfunction, Physiological Stress, Cognition - Other
Interventions
Yogurt with B. lactis and added honey, Yogurt with heat-inactivated B. lactis and added cane sugar
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
22 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Life-Stress Interview for Women With Chronic Urogenital Pain Conditions

NCT02286115
View directory record Official record
Conditions
Chronic Urogenital Pain
Interventions
Life-Stress Interview
Behavioral
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 13, 2016 · Synced Jul 21, 2026, 11:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Changes in Children and Adolescents With Behavioral Problems

NCT00104039
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood, Conduct Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 18 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Emotion Regulation Therapy for Clinical Worry and Rumination

NCT04060940
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression, Anxiety, Generalized Anxiety Disorder, Emotional Dysfunction
Interventions
Emotion Regulation Therapy: 8-session version, Emotion Regulation Therapy: 16-session version
Behavioral
Lead sponsor
Douglas Mennin
Other
Eligibility
18 Years to 29 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jul 21, 2026, 11:22 AM EDT
Completed Phase 4 Interventional

Wellbutrin XL Effects on SSRIs Induced Changes

NCT00456820
View directory record Official record
Conditions
Depression, Side Effects, Sexual Dysfunction, Apathy
Interventions
Wellbutrin XL
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 15, 2007 · Synced Jul 21, 2026, 11:22 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Maternal Choline Supplementation and Offspring Cognition in Adolescence

NCT05859126
View directory record Official record
Conditions
Cognitive Deficit in Attention, Executive Dysfunction, Emotional Regulation
Interventions
Maternal Choline Supplementation 930 mg/d, Maternal Choline Supplementation 480 mg/d
Dietary Supplement
Lead sponsor
Cornell University
Other
Eligibility
13 Years to 13 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jul 21, 2026, 11:22 AM EDT