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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:02 PM EDT

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Showing 121–144 of 269 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Emotional Stress Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluation of Stress Disorders

NCT00050804
View directory record Official record
Conditions
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Interventions
sertraline
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight

NCT03786016
View directory record Official record
Conditions
Resilience, Mood, Performance, Stress, Psychological
Interventions
8-Days in an Isolation, Confinement Unit
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 8, 2026, 1:02 PM EDT
Not yet recruiting Not applicable Interventional

Parenting-STAIR Modular for Military Fathers and OCONUS Families

NCT07843654
View directory record Official record
Conditions
Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship, Parent-Child Relationship, Parent-Child Relations, Stress Disorder, Post Traumatic, PTSD, Parenting, Child Behavior, Emotional Regulation, Emotion Regulation
Interventions
Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
Colorado Springs, Colorado • Silver Spring, Maryland • Lawton, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 8, 2026, 1:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Emotional Experiences in Fathers of NICU Infants

NCT00306605
View directory record Official record
Conditions
Stress, Depressive Symptomatology
Interventions
Questionnaire
Behavioral
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Male only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
2
States / cities
Newark, Delaware • Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 8, 2026, 1:02 PM EDT
Not listed Phase 1Phase 2 Interventional

Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2

NCT04846010
View directory record Official record
Conditions
Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder), Post-Infectious Arthritis, Post-Infectious Polyneuritis, Post-Infectious Parkinsonism, Post-Infectious Hypothyroidism, Post Infectious Osteoarthritis, Anxiety Disorders, Depression, Depression, Anxiety, Depression, Bipolar, Insomnia, GERD, Gastro Esophageal Reflux, Hepatitis, Glomerulonephritis
Interventions
PurWet, FurFat, PurApo, PurPhl, PurClo, PurInf, Smoliv
Combination Product
Lead sponsor
All Natural Medicine Clinic, LLC
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Success for Pre-K Teachers, Families and Children

NCT03524105
View directory record Official record
Conditions
Emotional Stress
Interventions
Program for Parents (Parenting Program), Thrive Professional Learning
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

rTMS for Emotional Difficulties in Verterans

NCT03749967
View directory record Official record
Conditions
Mental Health, Depression, rTMS, Anxiety, PTSD, Psychosocial Impairment
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Does Emotional Support Decrease In Vitro Fertilization Stress?

NCT01406028
View directory record Official record
Conditions
In Vitro Fertilization, Psychological Stress
Interventions
Phone calls
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2011 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Student Anxiety & Stress Study

NCT03986125
View directory record Official record
Conditions
Anxiety, Somatic Symptom Disorder
Interventions
Emotional Awareness & Expression Therapy, Mindfulness Meditation Training
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms

NCT01347749
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Phase 1 Interventional

Education Program to Manage Emotional Stress of Stem Cell Transplant Recipients and Their Caregivers

NCT00423774
View directory record Official record
Conditions
Family Caregivers, Bone Marrow Transplantation
Interventions
Problem-Solving Education
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 8, 2026, 1:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

STAIR for Trauma and Emotion Dysregulation

NCT05397613
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Borderline Personality Disorder, Emotion Regulation
Interventions
STAIR
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 8, 2026, 1:02 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Pre-Pilot: Problem Adaptation THerapy in Caregivers

NCT05567120
View directory record Official record
Conditions
Caregiver Burden
Interventions
PATH-Care
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Phase 2 Interventional

Expressive Writing for Reducing Stress and Diabetic Symptoms in Diabetes Patients

NCT00233142
View directory record Official record
Conditions
Diabetes Mellitus, Stress, Depression
Interventions
Expressive writing, Neutral writing
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
25 Years to 75 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
4
States / cities
Syracuse, New York • University Park, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Oct 8, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787
View directory record Official record
Conditions
Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions
webSTAIR, ExpoTx, PsychoEd
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 8, 2026, 1:02 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Human Stress Response in a Simulated ED Setting

NCT04317482
View directory record Official record
Conditions
Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence, Stress, Emotional
Interventions
Standard social stress task, Stressful experience in the ED
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 8, 2026, 1:02 PM EDT
Not yet recruiting No phase listed Observational

Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum

NCT07801079
View directory record Official record
Conditions
Depression, Anxiety, Addiction, Emotion, Craving, Stress
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 55 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 8, 2026, 1:02 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Professional Readiness Through Emotional Preparedness (PREP)

NCT07472127
View directory record Official record
Conditions
Burnout
Interventions
Professional Readiness through Emotional Preparedness (PREP) program
Behavioral
Lead sponsor
AdventHealth
Other
Eligibility
Not listed
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 8, 2026, 1:02 PM EDT
Withdrawn Not applicable Interventional

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD

NCT04543513
View directory record Official record
Conditions
PTSD, Cognitive Function
Interventions
Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Cognitive Adaptations to Reduce Emotional Stress Associated With Type 1 Diabetes

NCT03698708
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
CARES Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
5 Years to 12 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Online Positive Emotion Skills Intervention for Symptoms of Depression

NCT02861755
View directory record Official record
Conditions
Depression, Psychological Stress, Affect
Interventions
Positive Affect Skills Training, 5-week Emotion Reporting
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
677 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 8, 2026, 1:02 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Intervention Trial for Healthcare Workers With Anxiety

NCT06460285
View directory record Official record
Conditions
Anxiety
Interventions
EmRes, Mindfulness
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Motivations for Moms-to-be Study

NCT03063528
View directory record Official record
Conditions
Weight Gain, Pregnancy, Stress, Emotional, Exercise, Nutrition
Interventions
Healthy Eating and Physical Activity, Stress Reduction and Management
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
20 Years to 35 Years · Female only
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Oct 8, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Examining the Feasibility and Acceptability of a Tailored Version of a Mindfulness-Based Intervention (MBI) Among Youth Experiencing Homelessness (YEH)

NCT04950816
View directory record Official record
Conditions
Stress, Emotional
Interventions
tailored MBI (.b), attention control condition
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 8, 2026, 1:02 PM EDT