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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Endoscopic Submucosal Dissection Clear all
Recruiting No phase listed Observational

Multi-center Evaluation of the Clinical Utility of ESD in the Western Population

NCT02989818
View directory record Official record
Conditions
Endoscopic Submucosal Dissection
Interventions
Endoscopic Submucosal Dissection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
3
States / cities
Gainesville, Florida • Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Completed Not applicable Interventional

Endoscopic Myotomy of the Lower Esophageal Sphincter for Achalasia

NCT01399476
View directory record Official record
Conditions
Achalasia
Interventions
Endoscopic Myotomy, Endoscopic Myotomy for treatment of achalasia
Procedure
Lead sponsor
The Oregon Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Jun 10, 2026, 1:21 PM EDT
Withdrawn Not applicable Interventional

Monopolar and Bipolar in Esophageal ESD

NCT05736705
View directory record Official record
Conditions
Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electocautery
Interventions
Endoscopic Submucosal Dissection, Bipolar electrocautery knife
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

Utility of OverStitch Sx After ESD

NCT04361227
View directory record Official record
Conditions
Gastrointestinal Neoplasms
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Jun 10, 2026, 1:21 PM EDT
Not listed Phase 2 Interventional

Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia

NCT01302288
View directory record Official record
Conditions
Achalasia
Interventions
Per oral endolumenal myotomy
Procedure
Lead sponsor
The Oregon Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2011 · Synced Jun 10, 2026, 1:21 PM EDT
Recruiting Not applicable Interventional

Traction vs. No Traction in Colonic ESD

NCT06159634
View directory record Official record
Conditions
Gastrointestinal Neoplasm
Interventions
Endoscopic Submucosal Dissection, Traction Device
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

Endoscopic Submucosal Dissection Registry

NCT01415609
View directory record Official record
Conditions
Gastrointestinal Neoplasms, Gastric Cancer
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 8, 2012 · Synced Jun 10, 2026, 1:21 PM EDT
Recruiting Not applicable Interventional

Novel Rigidizing Overtube in Colonic Endoscopic Submucosal Dissection

NCT06134687
View directory record Official record
Conditions
Gastrointestinal Neoplasm
Interventions
Endoscopic Submucosal Dissection, Novel Rigidizing Overtube
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
22 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

Predicting Local and Distant Recurrence in T1 Colorectal Cancer

NCT06314971
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Neoplasms Malignant, Colorectal Cancer Recurrent
Interventions
Tw1CE
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

ConMed Beamer Study

NCT04752670
View directory record Official record
Conditions
Gastrointestinal Neoplasms, Achalasia, Gastroparesis
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Jun 10, 2026, 1:21 PM EDT
Not listed No phase listed Observational

Endoscopic Resection Multicenter Registry

NCT03065257
View directory record Official record
Conditions
Gastrointestinal Neoplasms, Gastrointestinal Disease, Gastric Cancer, Gastric Neoplasm, Gastric Polyp, Esophageal Neoplasms, Duodenal Neoplasms, Duodenal Polyp, Stomach Neoplasm, Stomach Polyp, Neoplasms, Colon Polyp, Colon Neoplasm
Interventions
Endoscopic Resection
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jun 10, 2026, 1:21 PM EDT
Active, not recruiting Not applicable Interventional

Monopolar Current Cutting Knife vs Bipolar RFA Knife

NCT04919824
View directory record Official record
Conditions
Gastrointestinal Neoplasms
Interventions
Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Completed Not applicable Interventional

Hybrid Versus Non-Hybrid Endoscopic Submucosal Dissection for Colorectal Polyps (SHORT-ESD)

NCT05347446
View directory record Official record
Conditions
Colorectal Lesions
Interventions
Hybrid ESD, Non-hybrid ESD
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
5
States / cities
Gainesville, Florida • Orlando, Florida • Fort Wayne, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

Pathfinder Registry

NCT05141032
View directory record Official record
Conditions
Gastrointestinal Polyps
Interventions
Endoscopic Submucosal Dissection with Pathfinder/Overtube device
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Jun 10, 2026, 1:21 PM EDT
Recruiting No phase listed Observational

Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions

NCT06476678
View directory record Official record
Conditions
Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electrocautery
Interventions
Speedboat™ Ultraslim
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Reduction With ESD- Versus APC-TORe

NCT06131281
View directory record Official record
Conditions
Obesity, Roux-en-y Anastomosis Site, Weight Gain
Interventions
E-TORe, c-TORe
Procedure
Lead sponsor
Stephen Firkins
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Not listed Phase 2 Interventional

Endolumenal Partial Myotomy for Esophageal Motility Disorders

NCT01302301
View directory record Official record
Conditions
Esophageal Motility Disorders
Interventions
Per oral endolumenal myotomy
Procedure
Lead sponsor
The Oregon Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2011 · Synced Jun 10, 2026, 1:21 PM EDT
Completed No phase listed Observational

Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD)

NCT04547881
View directory record Official record
Conditions
Esophageal Neoplasms
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Jun 10, 2026, 1:21 PM EDT
Completed Not applicable Interventional Results available

Closure of Mucosal and Submucosal Defects in the Gastrointestinal Tract Using the Novel X-Tack Endoscopic Suturing Device

NCT04925271
View directory record Official record
Conditions
Polyp of Colon, Fistula
Interventions
X-Tack, Overstitch
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Jun 10, 2026, 1:21 PM EDT
Recruiting Not applicable Interventional

Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon

NCT06015607
View directory record Official record
Conditions
Polyps Colorectal
Interventions
Control (via ESD using standard of care), GripTract
Device
Lead sponsor
Actuated Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Recruiting No phase listed Observational

Endoscopic Submucosal Dissection (ESD)

NCT05468008
View directory record Official record
Conditions
Esophageal Lesion, Barrett Esophagus, Gastrointestinal Lesions
Interventions
Endoscopic Submucosal Dissection
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jun 10, 2026, 1:21 PM EDT
Terminated Not applicable Interventional

Transanal Resection of Rectal Lesions With the ColubrisMX ELS System

NCT04651764
View directory record Official record
Conditions
Rectal Adenoma, Rectal Polyp, Rectal Lesion
Interventions
ColubrisMX Endoluminal Surgical (ELS) System
Device
Lead sponsor
ColubrisMX
Industry
Eligibility
22 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Orlando, Florida • Las Vegas, Nevada • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Jun 10, 2026, 1:21 PM EDT
Completed Not applicable Interventional

Evaluation of a Double Balloon Interventional Platform (DiLumen) for Complex Colonic ESD

NCT03846609
View directory record Official record
Conditions
Colonic Polyp
Interventions
double balloon interventional platform (DiLumen), no double balloon interventional platform (DiLumen)
Device
Lead sponsor
Mercy Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Jun 10, 2026, 1:21 PM EDT
Completed Phase 2 Interventional Results available

Prospective Evaluation of Budesonide for Prevention of Esophageal Strictures After Endotherapy

NCT02069847
View directory record Official record
Conditions
Esophageal Stricture
Interventions
Budesonide
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Jun 10, 2026, 1:21 PM EDT