Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:42 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 601–624 of 976 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Endothelial Clear all

Conditions: Diabetic Macular Edema, Cataract
Interventions: Aflibercept injected Pre- and Post-operatively, Aflibercept injected intraoperatively; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Fuchs' Endothelial Dystrophy
Interventions: Netarsudil, Placebo; Drug
Lead sponsor: Price Vision Group; Industry
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Fuchs' Endothelial Corneal Dystrophy
Interventions: K-321 Solution, Placebo Solution; Drug
Lead sponsor: Kowa Research Institute, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 19
States / cities: Los Angeles, California • Palo Alto, California • Sacramento, California + 14 more

Conditions: Corneal Endothelial Dystrophy, Fuchs Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy, Endothelial Dysfunction
Interventions: TTHX1114(NM141), Vehicle (placebo); Drug · Other
Lead sponsor: Trefoil Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 8
States / cities: Petaluma, California • Jacksonville, Florida • Hoffman Estates, Illinois + 5 more

Conditions: Cardiovascular Disease
Interventions: Not listed
Lead sponsor: National Institute of Environmental Health Sciences (NIEHS); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: Research Triangle Park, North Carolina

Conditions: Chronic Kidney Disease, Hypertension
Interventions: Procedure: Regional phenylephrine arterial infusion; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Macular Degeneration
Interventions: GW786034, Placebo; Drug · Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Austin, Texas • Tacoma, Washington

Conditions: HIV Infections
Interventions: Pravastatin, Gemfibrozil, Rosiglitazone; Drug
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: Not listed
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Fuchs Endothelial Corneal Dystrophy, Fuchs
Interventions: DT-168; Drug
Lead sponsor: Design Therapeutics, Inc.; Industry
Eligibility: 30 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Indianapolis, Indiana • Grand Rapids, Michigan

Conditions: Diabetic Macular Edema
Interventions: CU06-1004; Drug
Lead sponsor: Curacle Co., Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 10
States / cities: Deerfield Beach, Florida • Baltimore, Maryland • Hagerstown, Maryland + 7 more

Conditions: Hyperlipidemias
Interventions: DASH eating plan with eggs, DASH eating plan without eggs; Other
Lead sponsor: Griffin Hospital; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Derby, Connecticut

Conditions: Cataracts, Cataract Surgery
Interventions: Lens insertion during cataract surgery; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Type II Diabetes Mellitus
Interventions: Krill Oil (Supplement A), Placebo (Supplement B); Dietary Supplement
Lead sponsor: Danbury Hospital; Other
Eligibility: 18 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Danbury, Connecticut

Conditions: Insulin Resistance
Interventions: Dietary fat; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Endothelial Dysfunction
Interventions: Watermelon Juice; Dietary Supplement
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Epilepsy
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 4 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2019
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Diabetes Mellitus, Type 2
Interventions: 20 million Allogeneic Mesenchymal Human Stem Cells, 100 million Allogeneic Mesenchymal Human Stem Cells; Drug
Lead sponsor: Joshua M Hare; Other
Eligibility: 21 Years to 90 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Choroidal Neovascularization, Age-Related Maculopathy
Interventions: dexamethasone, ranibizumab, sham; Drug · Biological · Other
Lead sponsor: Allergan; Industry
Eligibility: 50 Years and older
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Boynton Beach, Florida

Conditions: Atherosclerosis, Peripheral Vascular Disease
Interventions: Magnetic resonance imaging; Procedure
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Metabolic Syndrome
Interventions: CAR-191, Placebo; Dietary Supplement · Other
Lead sponsor: Carmel Biosciences; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Diabetic Vascular Complications
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Healthy
Interventions: High potassium dietary education/counseling, Low sodium dietary education/counseling; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Type 2 Diabetes
Interventions: L-citrulline, Placebo; Dietary Supplement
Lead sponsor: Texas Tech University; Other
Eligibility: 40 Years to 75 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Lubbock, Texas

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Cataract DME - Peri vs. Intraop

Mechanism of Endothelial Dysfunction in Obstructive Sleep Apnea (OSA)

Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

A Phase 1/ Phase 2 Study of TTHX1114(NM141)

Blood Vessel Study

Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide

A Safety Study in Healthy Volunteers to Evaluate Safety, How Fast the Drug is Absorbed, and the Side Effects of the Drug in Humans

Endothelial Dysfunction as a Risk Factor in HIV Study

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

The Study of CU06-1004 in Patients With Diabetic Macular Edema (DME)

Daily Inclusion of Eggs in a Heart-Healthful Dietary Pattern in Hyperlipidemic Adults

Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection

Effects of Krill Oil on Endothelial Function in Patients With Type 2 Diabetes Mellitus

Does Class of Dietary Fat Affect Insulin Resistance?

The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function

Study of Specimens Obtained During Epilepsy Surgery

Allogeneic Mesenchymal Human Stem Cells Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects

Safety and Efficacy of a New Treatment as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment in Patients With Age-Related Macular Degeneration (AMD)

Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty

The BANGALORE Study; Combination of Berberine, Lipoic Acid, and Picrorhiza

Continuous Glucose Monitoring in Type 2 Diabetes Mellitus

Sodium vs Potassium Education to Improve Vascular Health

The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes