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ClinicalTrials.gov public records Last synced Nov 10, 2026, 6:08 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 976 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Endothelial Clear all

Conditions: Telangiectasia
Interventions: Ranibizumab; Drug
Lead sponsor: National Eye Institute (NEI); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Type 2 Diabetes, Chronic Kidney Disease
Interventions: Zemplar, Placebo; Drug
Lead sponsor: Scott and White Hospital & Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 4
States / cities: Atlanta, Georgia • New Orleans, Louisiana • Boston, Massachusetts + 1 more

Conditions: Endothelial Dysfunction
Interventions: Galantamine, Placebo, TENS 7000; Drug · Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Sleep Deprivation
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Diabetes Mellitus, Ischemic Heart Disease
Interventions: 100 million Allogeneic Mesenchymal Human Stem Cells, Placebo; Drug · Other
Lead sponsor: Joshua M Hare; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Healthy
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Male only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2003
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Vascular Aging
Interventions: Placebo, Sodium Nitrite; Drug
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 50 Years to 79 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Age Related Cognitive Decline, Alzheimer's Disease, Vascular Dementia, Endothelial Dysfunction, Executive Dysfunction
Interventions: Omega 3 PUFA, Placebo; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 75 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Alzheimer's Disease
Interventions: atorvastatin, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 40 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Hepatitis C
Interventions: Elbasvir/grazoprevir; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetes Mellitus, Type 2
Interventions: Zanamivir; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 45 Years to 64 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Type 2 Diabetes
Interventions: Hyperinsulinemic Hypoglycemic Clamp; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hypertension, Menopause
Interventions: L-Citrulline, Placebo; Dietary Supplement
Lead sponsor: Texas Tech University; Other
Eligibility: 50 Years to 75 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Nicotine Dependence
Interventions: e-cig with nicotine, e-cig without nicotine, nicotine inhaler, sham control; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hyperglycemia, Cardiovascular Disease
Interventions: Green Tea Concentrate; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 30 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Oxidative Stress
Interventions: Herbs and spices, High fat meal; Other
Lead sponsor: Penn State University; Other
Eligibility: 40 Years to 65 Years · Male only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Aging
Interventions: Hot yoga, Non-heated yoga; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 40 Years to 60 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions: High-resistance inspiratory muscle strength training, Aerobic exercise; Other
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 50 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Type 2 Diabetes
Interventions: Extra Virgin Olive Oil, Refined Olive Oil; Other
Lead sponsor: Griffin Hospital; Other
Eligibility: 25 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Derby, Connecticut

Conditions: Corneal Endothelial Dystrophy
Interventions: TTHX1114; Drug
Lead sponsor: Trefoil Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Atlanta, Georgia • Washington, Missouri

Conditions: Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia), Arterial Stiffness, Cognition, Oxidative Stress, Gut Microbiota, Overweight, Inflammation, Microvascular Function, Body Composition
Interventions: Wild Blueberry, Placebo; Dietary Supplement
Lead sponsor: Georgia State University; Other
Eligibility: 20 Years to 65 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Repeated Short Sleep Schedule
Interventions: repeated cycles of short sleep; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 25 Years to 55 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Fuchs, Fuchs Dystrophy, Fuchs' Endothelial Dystrophy
Interventions: Ripasudil, Placebo; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 8
States / cities: Palo Alto, California • Sacramento, California • Palm Beach Gardens, Florida + 3 more

Conditions: Diabetic Macular Edema
Interventions: Prompt Laser, Prompt aflibercept, Deferred laser, Deferred aflibercept; Procedure · Drug
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 702 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 100
States / cities: Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 84 more

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Injected Ranibizumab to Treat Macular Telangiectasia Without New Blood Vessel Formation

Effect Of Paricalcitol (Zemplar) On Endothelial Function And Inflammation In Type 2 Diabetes And Chronic Kidney Disease

Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents

Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD)

Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets

Sodium Nitrite to Treat Arterial Aging

n-3 PUFA for Vascular Cognitive Aging

Cerebral and Peripheral Perfusion Pilot Study

A Single-arm Evaluation of the Effect of HCV Treatment on Cardiovascular Disease Risk

Role of Neuraminidase Activity on Endothelial Dysfunction in Type 2 Diabetes

Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 4

8 Weeks of L-CIT Supplementation and LIRET on Vascular Function in Hypertensive Postmenopausal Women

E-cigarettes, Nicotine Inhaler, and Blood Vessel Function

Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction

The Acute Effect of Spices on Vascular Health

The Effect of Bikram Yoga on Arterial Stiffness and Endothelial Function in Middle-Aged Adults

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes

A Safety and Efficacy Trial of TTHX1114 in People With CED

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Repeated Challenge of Insufficient Sleep: Endothelial Effects

Descemet Endothelial Thickness Comparison Trial II

Treatment for CI-DME in Eyes With Very Good VA Study