Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 11, 2026, 7:38 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 976 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Endothelial Clear all

Conditions: Endothelial Function, Diabetes Mellitus, Hypertension
Interventions: carvedilol, metoprolol extended release; Drug
Lead sponsor: State University of New York - Downstate Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Obesity, Metabolic Syndrome
Interventions: Empagliflozin 25 MG, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: High Blood Pressure
Interventions: Nebivolol, Metoprolol XL; Drug
Lead sponsor: Emory University; Other
Eligibility: 21 Years to 80 Years
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Treatment Induced Hypertension
Interventions: Minoxidil, Hydralazine; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Coronary Artery Disease
Interventions: Omacor (omega-3-acid ethyl esters); Drug
Lead sponsor: Olive View-UCLA Education & Research Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Sylmar, California

Conditions: Vascular Stiffness, Endothelial Dysfunction, Diastolic Dysfunction
Interventions: Salsalate, Placebo (for salsalate); Drug
Lead sponsor: Gary L. Pierce; Other
Eligibility: 18 Years to 79 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Endothelial Dysfunction
Interventions: Watermelon Juice; Dietary Supplement
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
Interventions: Peanut group; Dietary Supplement
Lead sponsor: The University of Texas at Arlington; Other
Eligibility: 18 Years to 50 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Arlington, Texas

Conditions: Diabetic Macular Edema
Interventions: intravitreal ranibizumab 0.3 mg, dexamethasone intravitreal implant, Sham injection; Drug · Procedure
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 56
States / cities: Beverly Hills, California • Huntington Beach, California • Loma Linda, California + 47 more

Conditions: Dietary Modification, Cardiovascular Disease
Interventions: Chlorophyll complex, Standard Process, Betatene, sold as "Full Spectrum Carotenoid Complex", Small carotenoid-rich meals, Placebo; Dietary Supplement · Other
Lead sponsor: Bastyr University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Kenmore, Washington • Seattle, Washington

Conditions: Heart Failure With Reduced Ejection Fraction, Endothelial Dysfunction
Interventions: TVS, Sham TVS; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Hypertension
Interventions: Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO), Endothelial cell collection, Microvascular perfusion assessment using Definity; Drug · Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Locally Advanced Breast Cancer, Triple Negative Breast Cancer, Metastatic Triple Negative Breast Cancers
Interventions: BNT327 Dose Level 1 (DL1), BNT327 Dose Level 1 (DL2), Nab-placlitaxel, Carboplatin, Gemcitabine, Paclitaxel, Eribulin, BNT327 Optimized Dose, BNT327 Equivalent Q3W Dose; Drug
Lead sponsor: BioNTech SE; Industry
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 13
States / cities: Beverly Hills, California • Los Angeles, California • Palo Alto, California + 10 more

Conditions: Sickle Cell Anemia
Interventions: L-NMMA, Acetylcholine; Drug
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: Not listed
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2003
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity, Diabetes, Cardiovascular Diseases
Interventions: Exercise training; Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Smoking
Interventions: Varenicline, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Cardiovascular Diseases
Interventions: Blood volume collected specifically for this study; Biological
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 50 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Obesity, Vascular Dementia, Cognitive Impairment
Interventions: Urolithin A, Placebo; Dietary Supplement · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 40 Years to 64 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Endothelial Dysfunction
Interventions: Telmisartan; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Impact of Singing, Cardiovascular Health, Cardiovascular Risk Factors, Cardiovascular Diseases
Interventions: Not listed
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Heart Transplant
Interventions: L-arginine; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 8 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: HIV Infection, Cardiovascular Risk, HIV Infections
Interventions: Omega-3 study meal, Saturated fat study meal; Other
Lead sponsor: Tufts University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prediabetes
Interventions: Exercise, Without exercise; Behavioral
Lead sponsor: Baystate Medical Center; Other
Eligibility: 20 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Springfield, Massachusetts

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Coreg CR, Blood Vessel Stiffness and Blood Vessel Function

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension

Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension

The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease

Targeting Inflammation to Treat Cardiovascular Aging

The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function

Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals

Phase II Combination Steroid and Anti-VEGF for Persistent DME

Feeding the Rainbow to Investigate Endothelial Dysfunction

Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function and Arterial Stiffness in HFrEF

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Nitric Oxide to Improve Blood Flow in Sickle Cell Disease

Role of Adiposomes in Endothelial Dysfunction

Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus Placebo

Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea

The Role of the Space Environment on Vascular Endothelial and Smooth Muscle Cell Processes

Urolithin A Supplementation in Middle-aged Adults With Obesity

A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease

The Singing Heart Study

Prospective L-arginine Study

Postprandial Endothelial Dysfunction After a High-Fat Meal in HIV-infected Men

Effects of Aerobic Exercise in Patients With Pre-diabetes