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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:42 AM EDT

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Showing 433–456 of 469 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Endothelial Function Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Resistance Training Intervention on Vascular Function

NCT05451641
View directory record Official record
Conditions
Endothelial Function
Interventions
Blood flow restriction resistance training
Behavioral
Lead sponsor
Hirofumi Tanaka
Other
Eligibility
18 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 4 Interventional Results available

Effects of Switching Efavirenz to Raltegravir on Vascular Function and Bone Markers in HIV-infected Patients

NCT01270802
View directory record Official record
Conditions
HIV
Interventions
Tenofovir/emtricitabine, Tenofovir/emtricitabine/efavirenz, Raltegravir
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Oct 23, 2026, 10:42 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

NCT00573339
View directory record Official record
Conditions
Healthy
Interventions
Cardiac MRI
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
35 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 23, 2026, 10:42 AM EDT
Completed No phase listed Observational

Markers of Endothelial Function and Exercise CapaciTy in Patients With Left Ventricular Assist Devices (EFECT LVAD)

NCT01233037
View directory record Official record
Conditions
Endothelial Cells, Exercise Tolerance
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 5, 2016 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 4 Interventional Results available

Effect of Raltegravir on Endothelial Function in HIV-Infected Patients

NCT00843713
View directory record Official record
Conditions
HIV Infection, Inflammation, Cardiovascular Disease, HIV Infections
Interventions
raltegravir, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Oct 23, 2026, 10:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of the Relationship Between Blood Vessels and Insulin Response in Adolescents

NCT00374361
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Hypertension, Heart Disease, Stroke
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
8 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscadine Grape Seed Supplementation and Vascular Function

NCT01011517
View directory record Official record
Conditions
Dietary Supplements
Interventions
Muscadine grape seed supplement
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Oct 23, 2026, 10:42 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Endothelial Progenitor Cells (EPCs) and Type 2 Diabetes

NCT01176578
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Aerobic Exercise Training
Other
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
50 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes

NCT06016478
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
L-citrulline, Placebo
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
40 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating an Exercise Program to Reduce Cardiovascular Risk Factors in Children Infected With HIV

NCT00908284
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Cardiovascular Diseases
Interventions
Exercise Program, Control Group
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
2 Weeks to 25 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Oct 23, 2026, 10:42 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Resistance Training and Cardiometabolic Health

NCT03325933
View directory record Official record
Conditions
Insulin Sensitivity, Endothelial Dysfunction, Blood Pressure
Interventions
High Load/Low Rep Resistance Training, Low Load/High Rep Resistance Training
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Dietary Sodium Intake on Vascular Endothelium

NCT01550315
View directory record Official record
Conditions
Postural Tachycardia Syndrome (POTS)
Interventions
Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
Procedure · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 23, 2026, 10:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Endothelial Function in Young Hispanic Adults at Risk for Type 2 Diabetes

NCT01926938
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 40 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2013 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Exercise and Vascular Function in Chronic Kidney Disease

NCT02050035
View directory record Official record
Conditions
Chronic Renal Insufficiency
Interventions
Aerobic Exercise Training
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Investigation of Endothelium in Saphenous Vein Grafts

NCT01510821
View directory record Official record
Conditions
Endothelial Function of Saphenous Vein Grafts
Interventions
Use of Maquet Vasoshield Pressure-limiting syringe on SVG, Use of non-regulated syringe on SVG
Other
Lead sponsor
Emory University
Other
Eligibility
21 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2013 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease

NCT01068314
View directory record Official record
Conditions
Kidney Failure, Chronic
Interventions
Repetitive arm exercise
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 4 Interventional Results available

Growth Hormone and Endothelial Function in Children

NCT00373386
View directory record Official record
Conditions
Growth Hormone Deficiency, Panhypopituitarism, Short Stature
Interventions
growth hormone
Drug
Lead sponsor
Ohio State University
Other
Eligibility
8 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced Oct 23, 2026, 10:42 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia

NCT07715669
View directory record Official record
Conditions
Preeclampsia, Endothelial Function
Interventions
Paroxetine Hydrochloride, Ascorbic acid (Vitamin C)
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 23, 2026, 10:42 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Effect of Time-restricted Feeding on Physiological Function in Middle-aged and Older Adults

NCT02970188
View directory record Official record
Conditions
Aging
Interventions
Time Restricted Feeding
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Acute Effects of E-Cigarette Aerosol Inhalation

NCT03479203
View directory record Official record
Conditions
Endothelial Dysfunction, Biochemical Markers
Interventions
Electronic Cigarette Aerosol
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 35 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Sodium Nitrite to Treat Arterial Aging

NCT02022670
View directory record Official record
Conditions
Vascular Aging
Interventions
Placebo, Sodium Nitrite
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 79 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Lipemia and Metformin on Endothelial Function

NCT01037660
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Metformin
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2017 · Synced Oct 23, 2026, 10:42 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

GLP-1 and Hypoglycemia

NCT01858896
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Glucagon-Like Peptide- 1 (GLP-1) infusion, Placebo Comparator: Saline Infusion
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 23, 2026, 10:42 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

COMP-4 Supplementation and Brachial Artery FMD

NCT05595915
View directory record Official record
Conditions
Aging, Endothelial Dysfunction, Senescence
Interventions
COMP-4
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 39 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 23, 2026, 10:42 AM EDT