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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:52 AM EDT

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Showing 193–216 of 469 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Endothelial Function Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Juice Plus+® Supplementation on Endothelial Function in Overweight Men

NCT01533987
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Juice Plus
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Plasma Ceramides on Peripheral Vascular Function

NCT05107869
View directory record Official record
Conditions
Peripheral Vascular Disease, Lipid Disorder, Endothelial Dysfunction
Interventions
High Saturated Fat
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 40 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Phase 4 Interventional

Functional Change in Endothelium After Cardiac cAtheterization, With and Without Music Therapy

NCT01632670
View directory record Official record
Conditions
Coronary Artery Disease, Endothelial Dysfunction
Interventions
Music therapy
Other
Lead sponsor
Emmanouil Brilakis
Federal
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Proton Pump Inhibitors on Endothelial Function

NCT02022280
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
Lansoprazole, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 22, 2026, 4:52 AM EDT
Withdrawn Phase 2 Interventional

Effect of an Inhaled Glucocorticoid-long-acting Beta Adrenergic Agonist on Endothelial Function in COPD

NCT01209715
View directory record Official record
Conditions
COPD
Interventions
Placebo, Fluticasone /salmeterol
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Walnut Ingestion in Adults at Risk for Diabetes: Effects on Body Composition, Diet Quality, and Cardiac Risk Measures

NCT02330848
View directory record Official record
Conditions
Diabetes
Interventions
Walnut Ad libitum diet, Walnut Calorie controlled
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 22, 2026, 4:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function

NCT03062878
View directory record Official record
Conditions
Breast Cancer, Lymphoma, Chemotherapy Effect
Interventions
Arterial blood pressure, Vascular Ultrasound, Venous blood sample, Skin microcirculatory blood flow
Other
Lead sponsor
Carl Ade, M.S., Ph.D.
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Aliskiren on Endothelial Function in Pre-Diabetes and Diabetes

NCT01165983
View directory record Official record
Conditions
Diabetes Type 2
Interventions
Placebo, Aliskiren
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional

CoQ10 Biomarker Trial

NCT01408680
View directory record Official record
Conditions
Oxidative Stress, Inflammation, Endothelial Dysfunction
Interventions
Coenzyme Q10, Placebo
Dietary Supplement
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults

NCT01575288
View directory record Official record
Conditions
Vascular Aging
Interventions
Placebo, High-dose trehalose
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 79 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 11, 2015 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Estradiol+Drospirenone Versus Estradiol+MPA on Endothelial Function

NCT01109979
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Estradiol+MPA, Estradiol+Drospirenone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

NCT00608062
View directory record Official record
Conditions
Arterial Stiffening, Aging, Menopause
Interventions
GnRHant - Ganirelix acetate, Transdermal estradiol patch, Transdermal placebo patch
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 22, 2026, 4:52 AM EDT
Terminated Phase 4 Interventional Results available

Effect of Dapagliflozin on Inflammation and Endothelial Function

NCT02608905
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Dapagliflozin, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced Oct 22, 2026, 4:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Endothelial Function, Arterial Stiffness and Components

NCT01439217
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Not listed
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
8 Years to 28 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2013 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Phase 4 Interventional Results available

Effect of Raltegravir on Endothelial Function in HIV-Infected Patients

NCT00843713
View directory record Official record
Conditions
HIV Infection, Inflammation, Cardiovascular Disease, HIV Infections
Interventions
raltegravir, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Phase 4 Interventional Results available

The Effect of Exenatide Compared to Lantus Insulin on Vascular Function in Type 2 Diabetes

NCT00353834
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Exenatide, Glargine Insulin
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 22, 2026, 4:52 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

NCT06499844
View directory record Official record
Conditions
Endothelial Function
Interventions
Acetylcholine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 30 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Pressure Lowering Effects of Grape Juice

NCT00302809
View directory record Official record
Conditions
Hypertension
Interventions
Concord Grape Juice
Dietary Supplement
Lead sponsor
Boston University
Other
Eligibility
21 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2009 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effects of Negative Emotions on Endothelial Function

NCT01909895
View directory record Official record
Conditions
Emotions, Endothelial Dysfunction
Interventions
Anger Induction, Depressed Mood Induction, Anxiety Induction, Neutral emotion task
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Results available

Resveratrol and Vascular Function in CKD

NCT03597568
View directory record Official record
Conditions
Chronic Kidney Diseases, Endothelial Dysfunction
Interventions
Resveratrol, Placebo
Dietary Supplement · Other
Lead sponsor
Diana Jalal
Other
Eligibility
45 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 22, 2026, 4:52 AM EDT
Completed No phase listed Observational

Assessment of Endothelial Function, Apolipoproteins and Adiponectin

NCT01300390
View directory record Official record
Conditions
Cirrhosis
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals With Type 2 Diabetes Mellitus

NCT04511325
View directory record Official record
Conditions
Type2 Diabetes, Cardiometabolic Syndrome, Arterial Stiffness, Overweight and Obesity
Interventions
Potato Regimen, Refined Grain Regimen
Other
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease

NCT01038362
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
NCEP Step 1 diet plus Almonds, No Almonds
Other
Lead sponsor
Boston University
Other
Eligibility
21 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 23, 2009 · Synced Oct 22, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Centella Asiatica in Older Adults

NCT06472791
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
Centella Asiatica, Placebo Comparator
Dietary Supplement
Lead sponsor
National University of Natural Medicine
Other
Eligibility
50 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 22, 2026, 4:52 AM EDT