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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Energy Drink Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Caffeine Disposition After Inhalation

NCT02184104
View directory record Official record
Conditions
Healthy
Interventions
Caffeine
Dietary Supplement
Lead sponsor
University of Tennessee
Other
Eligibility
21 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Effects of Energy Drinks in Healthy Adults

NCT01940822
View directory record Official record
Conditions
Energy Drinks, Hemodynamics, Cardiovascular System
Interventions
Energy Drink, Placebo Drink
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Energy Shots and Caffeine for Energy and Wakefulness Levels

NCT01755299
View directory record Official record
Conditions
Focus: to Compare a Commercially Available Energy Drink, B Vitamins, Caffeine Alone, and Placebo for Effectiveness on Perceived Energy Level and Wakefulness
Interventions
Regular "5-hour Energy", Decaf "5-hour Energy", Compounded concentrated caffeine liquid, Flavored bottled water
Other
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Sylvania, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2013 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink

NCT06308731
View directory record Official record
Conditions
Substrate Oxidation, Energy Expenditure, Reaction Time, Cognition, Exercise Performance
Interventions
Caffeine-Based Energy Drink, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PFA-100 Responsive to Effect of Energy Drinks on Platelet Function

NCT02997111
View directory record Official record
Conditions
Platelet Function, Thrombosis
Interventions
PFA-100
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 35 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Energy Drink Consumption on ECG and Hemodynamic Parameters in Young Healthy Volunteers

NCT02023723
View directory record Official record
Conditions
Hemodynamic Effects of Energy Drink, Electrocardiograph Effects of Energy Drinks
Interventions
Energy Drink, Active Control
Dietary Supplement
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators

NCT05998096
View directory record Official record
Conditions
Energy Expenditure, Cognition, Reaction Time
Interventions
Caffeine-Based Energy Drink, Placebo
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Energy Drink Brands on Heart Rhythm

NCT03196908
View directory record Official record
Conditions
Electrical Alternation of Heart, Blood Pressure
Interventions
Energy Drink Brand 1, Energy Drink Brand 2, Placebo
Dietary Supplement · Other
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Energy Drinks on Sleep and Cardiovascular Health

NCT05503732
View directory record Official record
Conditions
Healthy, Caffeine
Interventions
Energy Drink, Placebo Drink
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism

NCT06330649
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Diet
Interventions
Energy Drink, Water Control
Dietary Supplement · Other
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 30 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption

NCT06137248
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Energy drink
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Examine the Effect of a Thermogenic Energy Drink in Healthy Adults

NCT05061797
View directory record Official record
Conditions
Metabolism
Interventions
Thermogenic Energy Drink - Active Study Product Formula, Placebo
Dietary Supplement
Lead sponsor
Rowdy Energy
Industry
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Fitness Drink Formulas on Energy Expenditure and Fat Metabolism

NCT04455009
View directory record Official record
Conditions
Caffeine, Diet, Healthy, Fat Burn, Cognitive Change, Fatigue
Interventions
Fitness Drink Formula
Dietary Supplement
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 35 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2020 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Caffeine on Heart Function

NCT02401776
View directory record Official record
Conditions
Fatigue, Tachycardia
Interventions
Monster Energy Drink, Coffee
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Energy Drinks

NCT02727920
View directory record Official record
Conditions
Energy Drinks
Interventions
Energy drink, Placebo
Dietary Supplement · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 70 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Jul 23, 2026, 3:23 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Effects of Energy Drinks on Cardiovascular Endpoints

NCT07212803
View directory record Official record
Conditions
Healthy Volunteers, Safety After Oral Intake
Interventions
Energy Drink A + Placebo Capsule, Placebo Drink + Moxifloxacin Capsule, Placebo Drink + Caffeine Capsule, Placebo Drink + Placebo Capsule, Energy Drink B, Control Product + Taurine, Control Product + Caffeine + Taurine, Lower Dose Energy Drink A
Dietary Supplement · Drug · Other
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 40 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Chronic Energy Drink Consumption on Cardiometabolic Endpoints

NCT03840863
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Commercially-Available Energy Drink
Dietary Supplement
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Energy Drink on Cardiovascular Variables: A Randomized Controlled Trial

NCT03841838
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Energy drink, Placebo drink
Other
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Post-Exercise Cardiovascular Responses Following Energy Drink Consumption

NCT03418077
View directory record Official record
Conditions
QTc Interval
Interventions
Energy Drink, Placebo-control
Dietary Supplement
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes

NCT05559372
View directory record Official record
Conditions
Caffeine, Exercise Performance, Energy Drink, Cardiovascular Safety, Mood
Interventions
Acute energy drink or placebo consumption
Dietary Supplement
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Effects of a Thermogenic Ready-to-drink Beverage

NCT05194475
View directory record Official record
Conditions
Metabolic Rate, Metabolism
Interventions
Thermogenic Ready-to-drink Beverage, Placebo Ready-to-drink Beverage
Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Jul 23, 2026, 3:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Energy Drink Ingredients on Cardiovascular Function in Men and Women 18-39 Years Old

NCT04149717
View directory record Official record
Conditions
Cardiac Arrhythmia, Blood Pressure
Interventions
Energy Drink Ingredients and Exercise
Dietary Supplement
Lead sponsor
Duquesne University
Other
Eligibility
18 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Jul 23, 2026, 3:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Energy Drinks and Vascular Function

NCT03324256
View directory record Official record
Conditions
Vascular Function
Interventions
energy drink, caffeinated drink, Energy gum, placebo gum, Control drink, Total sleep deprivation
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Jul 23, 2026, 3:23 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of Energy Drinks on Electrocardiographic, Vascular and Hematologic Parameters in Healthy Volunteers

NCT03021616
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
energy drink, Moxifloxacin 400mg, Placebo
Other
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Jul 23, 2026, 3:23 AM EDT