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Showing 1–24 of 439 matching trials from the live ClinicalTrials.gov search.
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Withdrawn Not applicable Interventional Accepts healthy volunteers

Low-calorie Diet in Isolated Impaired Fasting Glucose

NCT06451055
Conditions
Isolated Impaired Fasting Glucose
Interventions
Low-calorie diet, Routine dietary and physical activity habits
Behavioral
Lead sponsor
Emory University
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Atlanta, Georgia
Terminated No phase listed Observational Accepts healthy volunteers

Physical Activity in Adults With Amputation

NCT03722797
Conditions
Amputees
Interventions
Metabolic Cost Testing Procedures
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 60 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Malnutitrion, Cancer
Interventions
Indirect Calorimeter, Weight-Based Parenteral Nutrition Dosing
Device · Dietary Supplement
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Elevated Triglycerides, Hypertriglyceridemia
Interventions
Average American Diet With SoFAS Replaced With Avocado, Average American Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

CARE Trial: Comparing Different Levels of Calorie Reduction for Weight Loss

NCT02736669
Conditions
Overweight, Obesity
Interventions
Energy Reduction
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 75 Years
Enrollment
223 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition Intervention to Measure Metabolic Response in Children

NCT03139773
Conditions
Obesity, Childhood
Interventions
Control Breakfast Beverage, Omega-3 Breakfast Beverage
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
8 Years to 12 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fayetteville, Arkansas
Completed No phase listed Observational Accepts healthy volunteers

Effects of Aerobic Exercise Detraining

NCT02158130
Conditions
Motor Activity, Body Weight, Obesity
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 67 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Progressive Supranuclear Palsy
Interventions
Pyruvate, creatine, niacinamide, Placebo
Dietary Supplement
Lead sponsor
University of Louisville
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Effects of a Thermogenic Ready-to-drink Beverage

NCT05194475
Conditions
Metabolic Rate, Metabolism
Interventions
Thermogenic Ready-to-drink Beverage, Placebo Ready-to-drink Beverage
Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Prediabetes, Healthy (Controls)
Interventions
Ketone Monoester (KE), Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery

NCT03692507
Conditions
Major Abdominal/GI Surgery
Interventions
HMB, Protein and HMB, ERAS
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fresno, California
Completed Not applicable Interventional Accepts healthy volunteers

Activation of Brain Centers by Short-term Walnut Consumption in Obesity

NCT02673281
Conditions
Obesity
Interventions
Walnut shake, Placebo shake
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Bad Genes or Genes Behaving Badly

NCT01041664
Conditions
Body Composition, Energy Balance, Metabolism
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
3 Years to 7 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Basal Metabolic Rate in Postmenopausal Women

NCT01550536
Conditions
Postmenopausal Metabolic Health
Interventions
Resistance and aerobic exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 120 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
3
States / cities
La Jolla, California • San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers

Differential Metabolism of Dietary Fatty Acids

NCT00059254
Conditions
Obesity, Diabetes, Hyperlipidemia
Interventions
Oleic acid (OA), Palmitic Acid (PA)
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Galveston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Move and Moderate in Balance

NCT00715130
Conditions
Overweight, Obesity, Sedentary
Interventions
Energy Balance
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Obesity
Interventions
DEPTH, DEPTH-Morning, DEPTH-Evening
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
25 Years to 60 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

Electromyography and Yoga

NCT02818881
Conditions
Yoga
Interventions
High-speed yoga, Low-speed yoga
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Coral Gables, Florida
Conditions
Child Nutrition Disorders
Interventions
nutrition and hygiene education
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
1 Month to 6 Months
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Conditions
Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition, Energy Malnutrition Protein
Interventions
Total Knee Arthroplasty, Total Joint Arthroplasty
Procedure
Lead sponsor
University of Connecticut
Other
Eligibility
50 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Hartford, Connecticut
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Metabolic Effects of Natriuretic Peptide Hormones

NCT03397966
Conditions
Obesity, Cardiovascular Physiological Phenomena, Metabolism
Interventions
recombinant human BNP(1-32), placebo (control, normal saline)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 40 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee
Conditions
Obesity
Interventions
Glucagon, Placebo
Drug
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Obesity, Overweight
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Miami, Florida • Dilworth, Minnesota • Columbus, Ohio + 1 more
Conditions
Obesity, Normal Physiology, Healthy Volunteers
Interventions
+200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, fasting, -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +200% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein, -25% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona