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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Environmental Exposures Clear all
Recruiting Phase 1Phase 2 Interventional

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

NCT07226440
View directory record Official record
Conditions
Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
Interventions
Colesevelam, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Results available

Home Air Quality Impact for Adults With Asthma

NCT05224076
View directory record Official record
Conditions
Asthma, Environmental Exposure, Home Environment Related Disease
Interventions
Home Air Quality
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Pediatric Anxiety

NCT04504773
View directory record Official record
Conditions
Specific Phobia, Specific Phobia, Situational, Specific Phobia, Animal, Specific Phobia, Natural Environment, Childhood Anxiety Disorder
Interventions
Virtual Reality Exposure Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

NCT06357845
View directory record Official record
Conditions
Somatic Mutation
Interventions
Survey, Biological specimen collection, Communications about study updates and future research opportunities, Qualitative interview
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study

NCT07151235
View directory record Official record
Conditions
Healthy Participants
Interventions
Simulated wildfire smoke exposure, Clean Air exposure
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Reduction of Environmental Tobacco Smoke (ETS) Exposure In Pediatric Cancer Patients

NCT00766766
View directory record Official record
Conditions
Cancer
Interventions
Health Risk and Behavioral Skills Coaching Sessions, Telephone Coaching Sessions, Physician Feedback Letter
Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 17 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impacts of Clinician-Mediated Report-Back

NCT06074159
View directory record Official record
Conditions
Health Knowledge, Attitudes, Practice
Interventions
In-clinic report-back
Behavioral
Lead sponsor
Silent Spring Institute
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Developmental Impact of NICU Exposures (DINE)

NCT03061890
View directory record Official record
Conditions
Prematurity
Interventions
Not listed
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
Up to 12 Years
Enrollment
600 participants
Timeline
2017 – 2023
U.S. locations
11
States / cities
Jacksonville, Florida • Boston, Massachusetts • Minneapolis, Minnesota + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Natural History Study of Early Life Exposures in Agriculture (ELEA)

NCT07328516
View directory record Official record
Conditions
Prostate Cancer, Leukemia, Breast Cancer, Melanoma, Colorectal Cancer
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
64,277 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

American Lung Association (ALA) Lung Health Cohort

NCT04543461
View directory record Official record
Conditions
Lung Diseases
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years to 35 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
37
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 27 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

NCT00012480
View directory record Official record
Conditions
Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
3
States / cities
Los Angeles, California • Manhasset, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impacts of a Report-back Training Program

NCT06046872
View directory record Official record
Conditions
Behavioral Shift (Researcher Willingness to Report-back)
Interventions
Report-back training
Behavioral
Lead sponsor
Silent Spring Institute
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction Effects of Temperature and Ozone

NCT01981135
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean Air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Jul 23, 2026, 7:01 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water

NCT05395663
View directory record Official record
Conditions
Pollution; Exposure
Interventions
Community health worker
Behavioral
Lead sponsor
Oregon State University
Other
Eligibility
21 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)

NCT01840111
View directory record Official record
Conditions
Smoking, Healthy
Interventions
Quit Smoking 6 hours, Quit Smoking 24 hours
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Head Impact Exposure in Hawaii High School Football

NCT04020874
View directory record Official record
Conditions
Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
Interventions
HuTT-2x, HuTT-4x
Behavioral
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
14 Years to 19 Years
Enrollment
496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)

NCT00015587
View directory record Official record
Conditions
Leukemia, Acute Myelocytic Leukemia, Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
1 Day to 14 Years
Enrollment
3,523 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2016 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Pesticide Exposures in Child Care Centers

NCT03319927
View directory record Official record
Conditions
Children, Only, Risk Reduction, Environmental Exposure
Interventions
Changes in pesticide exposure, IPM Practices, Educational Workshops
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
3 Years to 75 Years
Enrollment
987 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers

NCT00690469
View directory record Official record
Conditions
Extraocular Retinoblastoma, Intraocular Retinoblastoma, Recurrent Retinoblastoma
Interventions
Laboratory Biomarker Analysis, Questionnaire Administration
Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Not listed
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
49
States / cities
Los Angeles, California • Madera, California • San Francisco, California + 38 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Jul 23, 2026, 7:01 AM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study

NCT07592858
View directory record Official record
Conditions
PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure, Burn Pit Exposure, Forever Chemicals, Hyperlipidemias, Hypercholesterolemia, Mixed Dyslipidemia, Hyperlipidemia (E.G., Hypercholesterolemia)
Interventions
Colesevelam, Placebo
Drug
Lead sponsor
University of Rhode Island
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Louisville, Kentucky • Augusta, Maine
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Mayo Clinic Precure - Prospective Study

NCT07332598
View directory record Official record
Conditions
Genetic Predisposition, Exposure, Environmental
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2035
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Service and Health Among Deployed Veterans

NCT02825654
View directory record Official record
Conditions
Pulmonary Function
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
6,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2029
U.S. locations
6
States / cities
San Diego, California • Decatur, Georgia • West Roxbury, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Research on the Environment and Children's Health: Retinoblastoma

NCT00582049
View directory record Official record
Conditions
Retinoblastoma
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2008 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2 Interventional

Prevention of Environmental Tobacco Smoke Exposure in Children 0-12 Months Old

NCT00340106
View directory record Official record
Conditions
Environmental Tobacco Smoke (ETS)
Interventions
Counseling
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 23, 2026, 7:01 AM EDT