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ClinicalTrials.gov public records Last synced Oct 28, 2026, 5:09 PM EDT

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Showing 1–24 of 391 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Epidural Clear all
Completed Phase 2 Interventional

A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery

NCT00200187
View directory record Official record
Conditions
Prostate Cancer
Interventions
low venous pressure general anesthesia, combined spinal-epidural anesthesia
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2007 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Phase 4 Interventional Results available

Loss of Resistance, w/wo Stimulation, For Epidural Placement

NCT03087604
View directory record Official record
Conditions
Anesthesia
Interventions
Thoracic epidural block, Electrical Nerve stimulation, Solution For Thoracic epidural block
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Leg Elevation to Prevent Hypotension During Labor

NCT05674838
View directory record Official record
Conditions
Hypotension, Labor Complication
Interventions
Leg Elevation
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia

NCT00487084
View directory record Official record
Conditions
Labor, Analgesia, Epidural
Interventions
Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 28, 2026, 5:09 PM EDT
Completed No phase listed Observational

The Use of Ultrasound to Measure Depth of Thoracic Epidural Space

NCT01172730
View directory record Official record
Conditions
Post Operative Trauma, Acute Pain
Interventions
Ultrasound scanning
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Oct 28, 2026, 5:09 PM EDT
Recruiting Not applicable Interventional

Trial of Underwater Birth

NCT07313319
View directory record Official record
Conditions
Birth
Interventions
Waterbirth
Procedure
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Early Phase 1 Interventional

Decreased Neuraxial Morphine After Cesarean Delivery

NCT04279054
View directory record Official record
Conditions
Anesthesia
Interventions
Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Results available

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

NCT05095454
View directory record Official record
Conditions
Paraplegia, Tetraplegia, Paralysis, Quadraplegia
Interventions
Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
22 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 28, 2026, 5:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes

NCT00810914
View directory record Official record
Conditions
Pain
Interventions
bupivicaine epidural, bupivicaine epidural infusion patient epidural, bupivicaine
Drug
Lead sponsor
MemorialCare
Other
Eligibility
18 Years and older · Female only
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2009 · Synced Oct 28, 2026, 5:09 PM EDT
Terminated Not applicable Interventional Results available

Acupuncture for Pre-Procedure Anxiety

NCT03480919
View directory record Official record
Conditions
Anxiety
Interventions
Shen Men acupuncture, Epidural injection
Device · Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 100 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 28, 2026, 5:09 PM EDT
No Longer Available No phase listed Expanded access

The Effect of Adding Magnesium Sulfate to Standard Epidural and Interscalene Block in Treatment of Patients With Chronic Pain

NCT01918514
View directory record Official record
Conditions
Pain
Interventions
Adding Magnesium Sulfate to the standard epidural and interscalene blocks for chronic pain
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
East Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 28, 2026, 5:09 PM EDT
Completed No phase listed Observational

Continuous Noninvasive Method for Estimating and Predicting Maternal and Fetal Hemodynamic Changes During Regional Anesthesia

NCT01699243
View directory record Official record
Conditions
Pregnancy, Anesthesia
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 44 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension

NCT05906368
View directory record Official record
Conditions
Anesthesia, Epidural, Hypotension
Interventions
ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
Diagnostic Test
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Results available

Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury

NCT04736849
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Tetraplegia, Paralysis
Interventions
Percutaneous epidural and dorsal root stimulation
Device
Lead sponsor
Peter J. Grahn, Ph.D.
Other
Eligibility
22 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 28, 2026, 5:09 PM EDT
Terminated Not applicable Interventional Results available

TEA vs. PVB vs. PCA in Liver Resection Surgery

NCT02192879
View directory record Official record
Conditions
Pain Management Strategies in Liver Resection Surgery
Interventions
thoracic epidural, continuous paravertebral catheter, Patient-Controlled Analgesia
Device · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT03353246
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 28, 2026, 5:09 PM EDT
Recruiting Phase 2Phase 3 Interventional

IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

NCT06559969
View directory record Official record
Conditions
Laparotomy
Interventions
Intravenous administered opioid, Epidural administered opioid
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Results available

CompuFlo Thoracic Epidural Study

NCT03826186
View directory record Official record
Conditions
Thoracic Epidural Anesthesia
Interventions
Traditional (loss-of-resistance technique) thoracic epidural placement, CompuFlo thoracic epidural placement
Device
Lead sponsor
YATISH SIDDAPURA RANGANATH
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 28, 2026, 5:09 PM EDT
Recruiting Not applicable Interventional

Epidural Stimulation After Neurologic Damage: Long-Term Outcomes

NCT05705453
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
Epidural Spinal Cord Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 28, 2026, 5:09 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base

NCT01192074
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 5, 2016 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Phase 4 Interventional Results available

Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain

NCT02226159
View directory record Official record
Conditions
Pain, Radiating
Interventions
Lidocaine, Lidocaine with Dexamethasone
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Peanut Labor Ball Following Epidural Anesthesia

NCT02190591
View directory record Official record
Conditions
Pregnancy
Interventions
Peanut Labor Ball
Device
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Phase 3 Interventional Results available

Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas

NCT01438476
View directory record Official record
Conditions
Liver Cancer, Pancreatic Cancer
Interventions
Intravenous Patient-Controlled Analgesia (IVPCA), Thoracic Epidural Analgesia (TEA), Questionnaires, Pain Assessment
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 28, 2026, 5:09 PM EDT
Completed Not applicable Interventional

The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.

NCT06319989
View directory record Official record
Conditions
Educational Problems
Interventions
Biplane Ultrasound, Single plane ultrasound
Other
Lead sponsor
University of Florida
Other
Eligibility
4 Months to 10 Years · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 5:09 PM EDT