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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Epidural/Anesthesia Clear all
Withdrawn Phase 3 Interventional

Study to Determine Whether the Instillation of 10ml Normal Saline Improves Epidural Analgesia During Labor

NCT01119079
View directory record Official record
Conditions
Parturients
Interventions
Normal Saline, Administration of epidural anesthesia for labor
Other · Procedure
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional

The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia

NCT02672397
View directory record Official record
Conditions
Labor Pain
Interventions
Additional Epidural Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery

NCT04117074
View directory record Official record
Conditions
Surgery, Analgesia
Interventions
Liposomal bupivacaine, Thoracic epidural analgesia (bupivacaine)
Drug · Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Early Phase 1 Interventional

Decreased Neuraxial Morphine After Cesarean Delivery

NCT04279054
View directory record Official record
Conditions
Anesthesia
Interventions
Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 3 Interventional Results available

Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

NCT04300231
View directory record Official record
Conditions
Cystectomy
Interventions
epidural bupivacaine 0.05%, Liposomal bupivacaine, bupivacaine 0.125%, bupivacaine 0.5%, /hydromorphone 0.05mg/ml, injectable saline
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Programmed Intermittent Epidural Bolus Time Interval and Injection Volume

NCT00417027
View directory record Official record
Conditions
Labor Pain
Interventions
Programmed Intermittent Epidural Bolus (PIEB)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 23, 2026, 1:45 PM EDT
Completed No phase listed Observational

Comparison of Epidural and TAP Block in Abdominal Surgery

NCT01848951
View directory record Official record
Conditions
Acute Pain, Surgery, Regional Anesthesia
Interventions
Epidural, TAP Block
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

Effect of Nitrous Oxide in Treating Neuropathic Pain: A Study in Chronic Low Back Pain Patients

NCT01172600
View directory record Official record
Conditions
Low Back Pain, Radiating Pain
Interventions
Entonox, Oxygen
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2016 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery

NCT00804609
View directory record Official record
Conditions
Epidural Analgesia, Obstetric
Interventions
DepoDur following epidural lidocaine, DepoDur following spinal anesthetic
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 4 Interventional Results available

Loss of Resistance, w/wo Stimulation, For Epidural Placement

NCT03087604
View directory record Official record
Conditions
Anesthesia
Interventions
Thoracic epidural block, Electrical Nerve stimulation, Solution For Thoracic epidural block
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Sep 23, 2026, 1:45 PM EDT
Terminated Phase 1 Interventional

Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain

NCT00373633
View directory record Official record
Conditions
THoracotomy
Interventions
Thoracic Epidural, Extrapleural Intercostal Catheter
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional

Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients

NCT01599403
View directory record Official record
Conditions
Traumatic Rib Fracture
Interventions
Paravertebral Block, Intercostal Nerve Block, Epidural Block
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 3 Interventional

Patient-Controlled Epidural Analgesia (PCEA) for Patients Who Have Had Major Open Gynecologic Surgery

NCT00136682
View directory record Official record
Conditions
Postoperative Pain
Interventions
patient-controlled epidural analgesia (PCEA), patient-controlled intravenous analgesia (PCA)
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2008 · Synced Sep 23, 2026, 1:45 PM EDT
Terminated Not applicable Interventional

Epidural Technique: Does it Really Matter to the Patient?

NCT03539796
View directory record Official record
Conditions
Anesthesia
Interventions
Dural puncture epidurals (DPE), Traditional epidurals (EPI), Combined-spinal epidural technique (CSE)
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia

NCT05487196
View directory record Official record
Conditions
Pregnancy Related
Interventions
Clonidine, Dexmedetomidine, Fentanyl, Ropivacaine
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional

Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.

NCT02086123
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Epidural Analgesia, Parenteral Analgesia (Intravenous)
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 23, 2026, 1:45 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base

NCT01192074
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 4, 2016 · Synced Sep 23, 2026, 1:45 PM EDT
Terminated Phase 4 Interventional Results available

Drug Concentration and Volume on Adequate Labor Analgesia With PIEB

NCT03553576
View directory record Official record
Conditions
Pain, Anesthesia, Labor Pain
Interventions
Low volume bolus, High volume bolus
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 23, 2026, 1:45 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients

NCT01309529
View directory record Official record
Conditions
Postoperative Retention of Urine, Postoperative Urinary Tract Infection
Interventions
Not listed
Lead sponsor
Memorial Health System
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 6, 2011 · Synced Sep 23, 2026, 1:45 PM EDT
Not listed Not applicable Interventional

Optimal Method of Pain Management in Patients With Multiple Rib Fractures

NCT01401712
View directory record Official record
Conditions
3 or More Rib Fractures
Interventions
ON-Q® Pain Relief System, Thoracic epidural catheter
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional

Paravertebral Catheters for Pancreatic Surgery

NCT02363777
View directory record Official record
Conditions
Acute Pain
Interventions
Epidural, Paravertebral catheters
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Sep 23, 2026, 1:45 PM EDT
Terminated Phase 2 Interventional Results available

Combined Spinal/Epidural (CSE) Saline Duration/Spread

NCT01062893
View directory record Official record
Conditions
Labor Pain
Interventions
Sterile normal saline 0 mls, 15 mls sterile normal saline
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
12 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

NCT04796935
View directory record Official record
Conditions
Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer, Obstetric Procedure Pain, Orthopedic Procedure Pain, Post-Dural Puncture Headache
Interventions
Tactile Imaging (VerTouch), Control (palpation)
Device · Other
Lead sponsor
IntuiTap Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
3
States / cities
Providence, Rhode Island • Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 23, 2026, 1:45 PM EDT
Completed Phase 3 Interventional Results available

Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas

NCT01438476
View directory record Official record
Conditions
Liver Cancer, Pancreatic Cancer
Interventions
Intravenous Patient-Controlled Analgesia (IVPCA), Thoracic Epidural Analgesia (TEA), Questionnaires, Pain Assessment
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Sep 23, 2026, 1:45 PM EDT