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Showing 1–24 of 170 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Epidural Analgesia Clear all
Completed Phase 3 Interventional Results available

Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

NCT03372161
View directory record Official record
Conditions
Lumbosacral Radicular Pain
Interventions
SP-102, Placebo
Drug
Lead sponsor
Scilex Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
37
States / cities
Mobile, Alabama • Phoenix, Arizona • Tempe, Arizona + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Jul 22, 2026, 9:05 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia

NCT05543694
View directory record Official record
Conditions
Labor Pain, Analgesia
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 9:05 PM EDT
Terminated Phase 2 Interventional Results available

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

NCT05017246
View directory record Official record
Conditions
Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
Interventions
Bupivacaine, Morphine, Lidocaine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Jul 22, 2026, 9:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cesarean Postoperative Pain Satisfaction

NCT00922142
View directory record Official record
Conditions
Cesarean
Interventions
Not listed
Lead sponsor
Saint Elizabeth Regional Medical Center
Other
Eligibility
14 Years to 40 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Phase 4 Interventional Results available

QL Block With Exparel in Colectomy

NCT03827291
View directory record Official record
Conditions
Laparotomy, Colectomy
Interventions
Exparel, Thoracic epidural analgesia
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional Results available

Presence of a Companion During Performance of Neuraxial Labor Analgesia

NCT02982213
View directory record Official record
Conditions
Anxiety, Pain, Health Knowledge, Attitudes, Practice
Interventions
Companion Present
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional

The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.

NCT06319989
View directory record Official record
Conditions
Educational Problems
Interventions
Biplane Ultrasound, Single plane ultrasound
Other
Lead sponsor
University of Florida
Other
Eligibility
4 Months to 10 Years · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional Results available

A Trial Comparing Combined Spinal- Epidural Dosing Strategies for External Cephalic Version

NCT01991743
View directory record Official record
Conditions
Pregnancy, Pain
Interventions
Group 2.5, Group 5, Group 7.5, Group 10
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Jul 22, 2026, 9:05 PM EDT
Terminated Phase 4 Interventional Results available

Two Dose Epidural Morphine for Post-cesarean Analgesia

NCT01844206
View directory record Official record
Conditions
Pain, Morphine Adverse Reaction
Interventions
Epidural Morphine, Epidural Saline
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional

Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia

NCT01861821
View directory record Official record
Conditions
Labor Pain
Interventions
Multiport flexible catheter, Uniport flexible catheter
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Jul 22, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Poke and a Placebo

NCT04497220
View directory record Official record
Conditions
Anesthesia
Interventions
Negative Connotation Langauge, Positive Connotation Language
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 22, 2026, 9:05 PM EDT
Active, not recruiting Phase 3 Interventional

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

NCT03214510
View directory record Official record
Conditions
Liver and Intrahepatic Bile Duct Disorder
Interventions
Bupivacaine, Fentanyl, Hydromorphone Hydrochloride, Implanted Medical Device, Liposomal Bupivacaine, Questionnaire
Drug · Device · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 9:05 PM EDT
Terminated Not applicable Interventional Results available

Combined Spinal Epidural Urinary Retention

NCT01597791
View directory record Official record
Conditions
Anesthesia, Pain, Urinary Retention
Interventions
Foley catheter, No foley catheter
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

DPE Technique in Labor Epidural for Morbidly Obese Women

NCT03074695
View directory record Official record
Conditions
Morbid Obesity, Labor Pain
Interventions
Dural puncture epidural (DPE), Standard Epidural (EPL), Dural puncture epidural (DPE), Standard Epidural (EPL)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery

NCT00380978
View directory record Official record
Conditions
Labor Pain, Pregnancy
Interventions
combined spinal epidural analgesia, late analgesia (systemic)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,026 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 9:05 PM EDT
Completed No phase listed Observational

Identification of L3-L4 Interspace in Parturients

NCT02697747
View directory record Official record
Conditions
Healthy
Interventions
Education
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
12 Years to 65 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Phase 2 Interventional Results available

Comparison of Loss of Resistance Techniques

NCT00638274
View directory record Official record
Conditions
Pain Relief
Interventions
Air, Saline
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Female only
Enrollment
356 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Leg Elevation to Prevent Hypotension During Labor

NCT05674838
View directory record Official record
Conditions
Hypotension, Labor Complication
Interventions
Leg Elevation
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jul 22, 2026, 9:05 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial

NCT00529074
View directory record Official record
Conditions
Analgesia
Interventions
Epidural Catheter for Analgesia
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Jul 22, 2026, 9:05 PM EDT
Terminated Phase 2 Interventional Results available

Combined Spinal/Epidural (CSE) Saline Duration/Spread

NCT01062893
View directory record Official record
Conditions
Labor Pain
Interventions
Sterile normal saline 0 mls, 15 mls sterile normal saline
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
12 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Jul 22, 2026, 9:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 22, 2026, 9:05 PM EDT
Terminated Not applicable Interventional Results available

Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine

NCT00616577
View directory record Official record
Conditions
Inguinal Herniorrhaphy, Orchiopexy
Interventions
Ropivacaine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 2 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

NCT02509312
View directory record Official record
Conditions
Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity, Coagulation Defect; Postpartum, Postoperative Pain, Ketorolac Adverse Reaction, Blood Loss, Postoperative
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Jul 22, 2026, 9:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of PIEB vs CEI for Labor Analgesia

NCT02949271
View directory record Official record
Conditions
Labor Pain
Interventions
Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Ropivacaine, Fentanyl
Other · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Jul 22, 2026, 9:05 PM EDT