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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:59 PM EDT

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Showing 73–96 of 190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Erectile Dysfunction Clear all
Completed Phase 2 Interventional

Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy

NCT00090376
View directory record Official record
Conditions
Impotence, Prostate Cancer
Interventions
GPI 1485
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
40 Years to 69 Years · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
25
States / cities
Phoenix, Arizona • La Mesa, California • Stanford, California + 19 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2008 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 2 Interventional Results available

A Study of Ejaculatory Dysfunction in Men With Low Testosterone Levels

NCT01419236
View directory record Official record
Conditions
Ejaculatory Dysfunction, Hypogonadism
Interventions
Testosterone Solution 2%, Placebo Solution
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
26 Years and older · Male only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Los Angeles, California • San Diego, California • New Orleans, Louisiana + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 19, 2026, 4:59 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Low Intensity Shockwave Therapy for Erectile Dysfunction

NCT04434352
View directory record Official record
Conditions
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy, Erectile Dysfunction Due to General Medical Condition, Erectile Dysfunction Due to Arterial Insufficiency
Interventions
Storz Duolith Low-Intensity Shockwave Therapy
Device
Lead sponsor
University of Virginia
Other
Eligibility
30 Years to 80 Years · Male only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional

Sham-Controlled Prospective Study Characterizing Erectile Tissue Ultrasound Changes Resulting From Penile LiSWT

NCT06600893
View directory record Official record
Conditions
Erectile Dysfunctions
Interventions
Low intensity shockwave therapy (LiSWT), Sham
Device
Lead sponsor
San Diego Sexual Medicine
Other
Eligibility
21 Years to 80 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 19, 2026, 4:59 PM EDT
Completed No phase listed Observational

Penile Injection Anxiety

NCT00582231
View directory record Official record
Conditions
Penile Injection Therapy, Erectile Dysfunction, Radical Pelvic Surgery
Interventions
Questionnaires.
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Male only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 19, 2026, 4:59 PM EDT
Terminated Not applicable Interventional Results available

Penile Lengthening Pre-Penile Prosthesis Implantation

NCT03500406
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
RestoreX, Control
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Tadalafil in Subjects With Erectile Dysfunction Caused by Spinal Cord Injury

NCT00421083
View directory record Official record
Conditions
Erectile Dysfunction, Spinal Cord Injuries
Interventions
tadalafil
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 25, 2007 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional Results available

Restore: Improving Sexual Outcomes of Gay and Bisexual Prostate Cancer Survivors

NCT03343093
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
Restore Rehabilitation Program, Control
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 19, 2026, 4:59 PM EDT
Terminated No phase listed Observational

Pudendal Assessment in Erectile Dysfunction

NCT01262833
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin

NCT01100021
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tamsulosin and avanafil, Doxazosin and avanafil
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
40 Years to 65 Years · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 7, 2011 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Dietary Pattern on Erectile Function

NCT04349059
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Animal based diet, Plant based diet
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 19, 2026, 4:59 PM EDT
Recruiting Phase 3 Interventional

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

NCT06945315
View directory record Official record
Conditions
Prostate Cancer, Erectile Dysfunction
Interventions
RALP (Robotic-assisted radical prostatectomy), SAFE (Saline assisted fascial engorgement)
Procedure · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Male only
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional

Therapy for Erectile Dysfunction Adaptation of ACT for Compliance With an Erectile Rehabilitation Program

NCT01275404
View directory record Official record
Conditions
Prostate Cancer
Interventions
Sexual Medicine Rehabilitation Program + nurse practitioner information phone calls, Sexual Medicine Rehabilitation Program + Acceptance and Commitment Therapy for Erectile Dysfunction
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 2 Interventional Results available

Evaluation of the 2005 AMS (American Medical System) IPP (Inflatable Penile Prosthesis)

NCT00636506
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
AMS 700 IPP with MS Pump
Device
Lead sponsor
American Medical Systems
Industry
Eligibility
21 Years and older · Male only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
7
States / cities
Indio, California • New Port Richey, Florida • Shreveport, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 19, 2026, 4:59 PM EDT
Recruiting Not applicable Interventional

Penile Lengthening Pre-Penile Prosthesis Implantation

NCT07053826
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Penile Traction Device, Inflatable Penile Prosthesis Implantation
Device · Procedure
Lead sponsor
J. Peter Rubin, MD
Other
Eligibility
18 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 19, 2026, 4:59 PM EDT
Terminated Phase 4 Interventional Results available

PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

NCT00867815
View directory record Official record
Conditions
Anterior Ischemic Optic Neuropathy
Interventions
Diagnostic procedures
Drug
Lead sponsor
Bayer
Industry
Eligibility
40 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
11
States / cities
Vista, California • Atlantis, Florida • Fort Myers, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 2 Interventional

Phase 2a Topical Sildenafil Proof-of-Concept Study in Men With Mild to Moderate ED

NCT02390960
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Sildenafil Cream, Placebo Cream, Penile Plethysmography (RigiScan)
Drug · Device
Lead sponsor
Strategic Science & Technologies, LLC
Industry
Eligibility
18 Years to 70 Years · Male only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
San Diego, California • New Orleans, Louisiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Treatment Continuation in Telehealth Patients Receiving an Automated Patient-Reported Outcome Tool

NCT05895539
View directory record Official record
Conditions
Internet-based Intervention, Web-based Intervention, Online Intervention, Erectile Dysfunction, Telemedicine
Interventions
An automated patient-reported outcome data collection and adverse event surveillance tool
Other
Lead sponsor
Ro
Industry
Eligibility
18 Years and older · Male only
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 19, 2026, 4:59 PM EDT
Recruiting Not applicable Interventional

EndoPAT Device for Endothelial Dysfunction in ED

NCT06720597
View directory record Official record
Conditions
Erectile Dysfunction, Hypogonadism, Male, Endothelial Dysfunction
Interventions
Daily low-dose PDE5 inhibitor therapy, Testosterone therapy as per clinical guidelines.
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 19, 2026, 4:59 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Study to Compare the Effects of Viagra® Vs Hezkue® in Healthy Fasted Male Participants.

NCT06782659
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
ASP-001, Viagra, ASP-001
Drug · Device
Lead sponsor
Aspargo Labs, Inc
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Not applicable Interventional Results available

Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction

NCT04136288
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
MoreNova
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 55 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 19, 2026, 4:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bone Density and Serum Testosterone in Male Methadone Maintained Patients

NCT00170339
View directory record Official record
Conditions
Opiate Dependence, Osteoporosis, Erectile Dysfunction, Hypogonadism
Interventions
Not listed
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2016 · Synced Oct 19, 2026, 4:59 PM EDT
Completed Phase 4 Interventional

A Multicenter, Double-blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Sildenafil on the As-Needed Efficacy of Viagra in Men With Erectile Dysfunction and Type 2 Diabetes

NCT00645268
View directory record Official record
Conditions
Erectile Dysfunction, Diabetes Mellitus, Type 2
Interventions
sildenafil, placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
35 Years to 70 Years · Male only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
28
States / cities
Huntsville, Alabama • Phoenix, Arizona • Beverly Hills, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Oct 19, 2026, 4:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Yohimbine and Naltrexone on Sexual Function

NCT00042536
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Naltrexone HCL/ Yohimbine HCL
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 19, 2026, 4:59 PM EDT