Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 281 matching trials from the live ClinicalTrials.gov search.
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Not listed Not applicable Interventional Accepts healthy volunteers

Soluble Corn Fiber for Promoting Executive Function Study

NCT05066425
Conditions
Health
Interventions
Soluble Corn Fiber, Maltodextrin
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Cognitive Impairment, Executive Dysfunction, Acquired Brain Injury
Interventions
Multicontext (MC) approach
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Assessment of Sensory Gating, Attention, and Executive Control in Breast Cancer

NCT03619083
Conditions
Breast Cancer
Interventions
SAE battery, Assessments
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Aerobic Exercise in Parkinson's Disease

NCT03808675
Conditions
Parkinson's Disease
Interventions
Aerobic walking, Usual care with PD specific health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa
Conditions
Cognitive Impairment, Mild
Interventions
Telerehabilitation Experimental Group, Telerehabilitation Sham Control Group
Device · Other
Lead sponsor
Bright Cloud International Corp
Industry
Eligibility
20 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
New Brunswick, New Jersey • North Brunswick, New Jersey
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise, Executive Processes and the Aging Brain

NCT00430976
Conditions
Cognition, Aging
Interventions
Minds in Motion
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 74 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Breast Cancer
Interventions
12 month exercise and weight loss intervention
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 69 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Parkinson Disease
Interventions
Temporary implatation of large-scale intracranial electrode., brain electrode
Procedure · Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Cognitive Performance, Attention, Reaction Time, Caffeine
Interventions
Caffeinated Coffee, Decaffeinated Coffee Placebo
Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Smoothie Program for Achieving and Resilient Kids

NCT07195474
Conditions
Executive Functions (EF), Microbiome, Dietary Quality
Interventions
Yogurt Smoothie (1 per day), Yogurt Smoothie (2 per day), Fruit Juice Control
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
7 Years to 9 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
State College, Pennsylvania
Conditions
School Readiness, Developmental Delays
Interventions
Early Intervention Foster Care (EIFC)
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
3 Years to 6 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Major Depressive Disorder
Interventions
SPD489 (Lisdexamfetamine dimesylate), Matching placebo
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years to 55 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
33
States / cities
Imperial, California • Los Alamitos, California • Oceanside, California + 28 more
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Entorhinal Cortex and Aerobic Exercise in Aging

NCT02775760
Conditions
Aging
Interventions
Cardiovascular endurance, Strength, balance, and flexibility
Behavioral
Lead sponsor
Boston University
Other
Eligibility
60 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers Results available

Body Temperature in Persons With Tetraplegia When Exposed to Heat

NCT01890915
Conditions
Spinal Cord Injury
Interventions
Heat Exposure
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Mild Cognitive Impairment, Chronic Kidney Diseases
Interventions
Home-based walking exercise, Attention control
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
55 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

IMProving Executive Function Study

NCT03187353
Conditions
Cognitive Impairment, RRSO
Interventions
Lisdexamfetamine, Placebo oral capsule
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
35 Years to 58 Years · Female only
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking Sitting with High-intensity Interval Training for Brain Health

NCT06243016
Conditions
Aging
Interventions
High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Acceptance-based Care for Child Eating and Physical Activity Treatment

NCT03368716
Conditions
Pediatric Obesity, Executive Function, Self-Regulation
Interventions
Acceptance-based Behavioral Treatment (ABBT)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
8 Years to 12 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

NCT06605898
Conditions
Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
Interventions
MIND Diet, Control Diet
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
45 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Emotion Regulation in Binge Eating and Purging Among Adolescents

NCT03429114
Conditions
Binge Eating, Purging (Eating Disorders)
Interventions
Magnetic resonance imaging
Other
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Stanford, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Do Motor Synchrony Games Improve Self Regulation?

NCT06647693
Conditions
Preschool Child, Executive Function (Cognition)
Interventions
Motor Synchrony Games (MSG)
Behavioral
Lead sponsor
Appalachian State University
Other
Eligibility
2 Years to 5 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boone, North Carolina
Conditions
Brain Injury
Interventions
training in goal-directed attention regulation, brain health education, computer-assisted training in goal-directed attention regulation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Sacramento, California
Conditions
Healthy Volunteers
Interventions
Rhodiola rosea (low dose), Rhodiola rosea (high dose), Placebo capsules
Dietary Supplement
Lead sponsor
Jacksonville State University
Other
Eligibility
18 Weeks to 40 Weeks
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Jacksonville, Alabama
Conditions
Attention Deficit Hyperactivity Disorder (ADHD), Executive Function Deficits (EFD)
Interventions
Placebo, Memantine Hydrochloride, OROS-Methylphenidate
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts