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ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:09 PM EDT

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Showing 1–24 of 285 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Executive Functioning Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy

NCT01986777
View directory record Official record
Conditions
Cognitive Impairments, RRSO
Interventions
lisdexamfetamine, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 60 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Oct 17, 2026, 3:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Training Inner Speech in Children With Developmental Language Disorder

NCT06880731
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
Modeling with Verbal Mediation, Modeling Only
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
8 Years to 10 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of 1072nm Infrared Stimulation on Executive Functioning in Dementia

NCT01059877
View directory record Official record
Conditions
Dementia
Interventions
1072nm infrared Photobiomodulation, Photobiomodulation SIMULATED
Device
Lead sponsor
Quietmind Foundation
Other
Eligibility
50 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Plymouth Meeting, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Modeling and Testing Change in Mental Abilities in Childhood

NCT02459873
View directory record Official record
Conditions
Low Executive Function in Children
Interventions
Computer games to assess change in executive function skills
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
84 Months to 132 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Results available

Development of a Mobile App for an Executive Functioning Intervention for Adolescents

NCT04018794
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder Symptoms
Interventions
Behavioral/organizational skills intervention augmented with digital health application
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years to 15 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study

NCT02642029
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder I
Interventions
Excitatory TMS, Inhibitory TMS, Sham TMS
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Belmont, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 30, 2022 · Synced Oct 17, 2026, 3:09 PM EDT
Recruiting Not applicable Interventional

Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture

NCT07635940
View directory record Official record
Conditions
Psychopathy
Interventions
continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS), Sham
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 17, 2026, 3:09 PM EDT
Terminated Phase 4 Interventional Results available

Antipsychotic Effects on Brain Function in Schizophrenia

NCT01913327
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
Interventions
Aripiprazole, Risperidone, Modafinil
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 40 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Phase 2 Interventional Results available

SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder

NCT00985725
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
SPD489 (Lisdexamfetamine dimesylate), Matching placebo
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years to 55 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
33
States / cities
Imperial, California • Los Alamitos, California • Oceanside, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rhythmically Entrained Exercise in Community-Dwelling Older Adults

NCT05462977
View directory record Official record
Conditions
Exercise, Gait, Cognitive Decline, Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Mild Cognitive Impairment, Respite Care, Mental Health, Depression, Music Therapy, Psychosocial Intervention, Cognition, Geriatric Assessment, Cognitive Dysfunction, Cognitive Aging, Outcome Assessment, Health Care, Balance, Fall, Walking, Affect, Physical Exertion, Memory Deficit, Memory Disorders, Memory Impairment, Neuropsychological Tests, Executive Function, Middle Aged, Healthy Aging, Elderly
Interventions
Group exercise program
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
55 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Results available

Aerobic Exercise in Parkinson's Disease

NCT03808675
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Aerobic walking, Usual care with PD specific health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurotrophic Indicators of Cognition, Executive Skills, Plasticity, and Adverse Childhood Experiences Study

NCT04076722
View directory record Official record
Conditions
Weight Loss, Wait-List Control
Interventions
Stress reactivity stimuli
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 19, 2021 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptance-based Care for Child Eating and Physical Activity Treatment

NCT03368716
View directory record Official record
Conditions
Pediatric Obesity, Executive Function, Self-Regulation
Interventions
Acceptance-based Behavioral Treatment (ABBT)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
8 Years to 12 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 17, 2026, 3:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients

NCT01043432
View directory record Official record
Conditions
Traumatic Brain Injury, Suicidality
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Results available

Novel Executive Function Training for Obesity

NCT03724396
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss - BWL, Novel Executive Function Training - NEXT
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 17, 2026, 3:09 PM EDT
Not listed Not applicable Interventional

The Influence of the Otago Exercise Program on Executive Function Among People Living With Mild to Moderate Dementia

NCT05488951
View directory record Official record
Conditions
Dementia
Interventions
Otago Exercise Program
Other
Lead sponsor
Augusta University
Other
Eligibility
55 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Results available

Diabetes Journey: An Adolescent Adherence Barriers Intervention

NCT04404556
View directory record Official record
Conditions
Type 1 Diabetes, Adherence, Patient
Interventions
Diabetes Journey, Enhanced Standard of Care
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 17 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Gainesville, Florida • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Sedation on Cognitive Performance in the Elderly

NCT03089866
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction
Interventions
Midazolam (0.02mg/kg)
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Active, not recruiting Not applicable Interventional

Optimizing CBSST With Executive Function Training for Schizophrenia

NCT06251193
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
E-CBSST
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short-Term Rhodiola Rosea for Anaerobic Performance and Cognitive Function in Resistance-Trained Adults

NCT07225413
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Rhodiola rosea (low dose), Rhodiola rosea (high dose), Placebo capsules
Dietary Supplement
Lead sponsor
Jacksonville State University
Other
Eligibility
18 Weeks to 40 Weeks
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Jacksonville, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

NCT01194661
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke, Headache, PTSD
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 40 Years
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 17, 2026, 3:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Control & the Functional Organization of the Frontal Cortex

NCT06436209
View directory record Official record
Conditions
Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers, Executive Function
Interventions
Multitask Practice Intervention (MPI), Single-task Practice Intervention (SPI)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 17, 2026, 3:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cybercycling for Cognitive Health

NCT01167400
View directory record Official record
Conditions
Cognitive Ability, General
Interventions
Cybercycling, Traditional exercise
Behavioral
Lead sponsor
Union College, New York
Other
Eligibility
50 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
8
States / cities
Colonie, New York • Malta, New York • Niskayuna, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2014 · Synced Oct 17, 2026, 3:09 PM EDT
Not listed Not applicable Interventional

Effectiveness of EEG Neurofeedback in Pediatric Occupational Therapy to Improve Executive Functioning

NCT04221620
View directory record Official record
Conditions
Executive Functioning, Pediatric ALL
Interventions
Zengar Electroencephalogram (EEG) Neurofeedback device
Device
Lead sponsor
Northern Arizona University
Other
Eligibility
6 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Prescott, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Oct 17, 2026, 3:09 PM EDT