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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Physical Activity
Interventions
Isometric Contraction Exercise - Young Adults (Age group 18-39), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59), Isometric Contraction Exercise - Old Adults (Age group >60)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Nutritional Supplement, Eccentric Exercise and Recovery

NCT01444170
Conditions
Injury, Inflammation
Interventions
dicreatinol sulfate, placebo sugar pill
Dietary Supplement · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Exercise, Isometric
Interventions
Isometric exercises, No exercise
Other
Lead sponsor
Carrick Institute for Graduate Studies
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cape Canaveral, Florida
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Exercise
Procedure
Lead sponsor
University of Saskatchewan
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Anterior Knee Pain Syndrome
Interventions
Knee Isometric Program (KIP)
Behavioral
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Response to Isometric BFR Exercise

NCT06529068
Conditions
Blood Pressure
Interventions
Isometric handgrip exercise, Isometric handgrip exercise with a narrow-elastic band, Isometric handgrip exercise with a wide-rigid cuff
Behavioral
Lead sponsor
Hirofumi Tanaka
Other
Eligibility
18 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Conditions
Orthostatic Intolerance
Interventions
LBNP, LBNP + Isometric handgrip exercise
Other
Lead sponsor
Tracy Baynard
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

L-citrulline Supplementation & Cold Exposure

NCT01462591
Conditions
Hypertension
Interventions
L-citrulline
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tallahassee, Florida
Not listed Not applicable Interventional Accepts healthy volunteers

Collagen Protein Versus Placebo on Muscle Recovery

NCT06465407
Conditions
Anthropometrics: Height and Weight, Isometric Standing and Seated Plantarflexion, Calf Muscle Thickness, Achilles Tendon Length and Thickness, Myotonography of the Calf Musculature and Achilles Tendon, Pain Pressure Threshold of the Calf, Pain Scale, Endurance Calf Test, Dietary Analysis
Interventions
Collagen, Maltodextrin
Dietary Supplement
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Tendinopathy
Interventions
Isometric Exercise, Sham Transcutaneous Electrical Nerve Stimulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 28 Years · Male only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Brief Periods of Exercise on Blood Pressure

NCT07453550
Conditions
Hypertension (HTN), Pre Hypertension
Interventions
wall-squat, wall-squat-tradition
Behavioral
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
West Hartford, Connecticut
Conditions
Osteoarthritis
Interventions
Isometric exercise
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
6
States / cities
Trumbull, Connecticut • Moorestown, New Jersey • Rochester, New York + 3 more
Conditions
Hypertension, Systolic
Interventions
Zona Plus Device, Control Device
Device
Lead sponsor
Zona Health, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
St Louis, Missouri • Charlotte, North Carolina • Goldsboro, North Carolina + 2 more
Conditions
Dysphagia
Interventions
Isometric Progressive Resistance Oropharyngeal Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 95 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
9
States / cities
Evanston, Illinois • Lexington, Kentucky • Minneapolis, Minnesota + 5 more
Conditions
Sports
Interventions
Red Spinach Extract (RSE), Placebo
Dietary Supplement
Lead sponsor
Lipscomb University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Therapy, Exercise
Interventions
Isometric exercises, Eccentric exercises
Other
Lead sponsor
Carrick Institute for Graduate Studies
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cape Canaveral, Florida
Completed Phase 2 Interventional Results available

Twice Weekly Steroids and Exercise as Therapy for DMD

NCT04322357
Conditions
Duchenne Muscular Dystrophy (DMD)
Interventions
Prednisone, Exercise Training on standard steroid regimen, Exercise training on twice-weekly steroids
Drug · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 9 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Not yet recruiting Not applicable Interventional

Handgrip Exercise Training and CKD

NCT07094906
Conditions
Chronic Kidney Diseases
Interventions
Isometric handgrip exercise training, Sham Training
Device
Lead sponsor
Emory University
Other
Eligibility
45 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Sex Effects on Blood Pressure With Handgrip Training

NCT06215014
Conditions
Blood Pressure
Interventions
Isometric handgrip training
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 40 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Acute Cryotherapy on Musculoskeletal Function and Biomarkers

NCT07211412
Conditions
Exercise Induced Muscle Damage, Cryotherapy
Interventions
Cryotherapy, Eccentric exercise-induced muscle damage
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Isometric Exercise and Endogenous Pain Inhibition

NCT03778476
Conditions
Fibromyalgia
Interventions
Isometric Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
Interventions
Botulinum toxin type A, Isometric Yoga-like exercise, Placebo
Drug · Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
14 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Manhattan, New York
Conditions
Syncope
Interventions
Tilt table test
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Exercise
Interventions
Exercise
Procedure
Lead sponsor
University of South Dakota
Other
Eligibility
18 Years to 64 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Vermillion, South Dakota