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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Exercise Induced Muscle Damage Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals

NCT05100459
View directory record Official record
Conditions
Muscle Damage, Muscle Soreness
Interventions
Pasture-raised whey protein, Conventional whey protein, Placebo
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein and Recovery From Exercise-induced Muscle Damage

NCT02034721
View directory record Official record
Conditions
Muscle Damage, Inflammation
Interventions
Protein supplement, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Astaxanthin, Exercise Inflammation, Skin Health

NCT05409092
View directory record Official record
Conditions
Inflammatory Response, Metabolic Disturbance, Immune Suppression
Interventions
Astaxanthin, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 57 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effects of a Novel Dietary Microalgae Based Ingredient on Muscle Recovery and Endurance Capacity

NCT05760742
View directory record Official record
Conditions
Healthy
Interventions
MicAlgae, Placebo
Dietary Supplement
Lead sponsor
Microphyt
Industry
Eligibility
18 Years to 35 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Turmeric and Exercise-Induced Muscle Damage and Oxinflammation

NCT04765527
View directory record Official record
Conditions
Muscular Injury
Interventions
Turmeric Strength for Joint, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 50 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 20, 2021 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

LycoRed 40051 Product as a Countermeasure to Exercise Stress

NCT02369666
View directory record Official record
Conditions
Inflammation
Interventions
LycoRed (code 40051) product, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Nutritional Supplement, Eccentric Exercise and Recovery

NCT01444170
View directory record Official record
Conditions
Injury, Inflammation
Interventions
dicreatinol sulfate, placebo sugar pill
Dietary Supplement · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pea Protein Supplementation and Muscle Damage

NCT03448328
View directory record Official record
Conditions
Muscular Injury
Interventions
NUTRALYS pea protein supplement, Whey Protein, Apple juice
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men

NCT03760757
View directory record Official record
Conditions
Inflammation; Muscle
Interventions
ESPO-572®, PCSO-524®
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Jun 7, 2026, 11:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Acute Cryotherapy on Musculoskeletal Function and Biomarkers

NCT07211412
View directory record Official record
Conditions
Exercise Induced Muscle Damage, Cryotherapy
Interventions
Cryotherapy, Eccentric exercise-induced muscle damage
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance

NCT06795425
View directory record Official record
Conditions
Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness, Immune Function, Gut Health, Microbiome Analysis, Exercise Performance, Exercise Metabolism
Interventions
Postbiotic Active Lifestyle Blend, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

NCT07219498
View directory record Official record
Conditions
Exercise Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Interventions
Lactobacillus casei, Placebo Capsule(s)
Dietary Supplement · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 30 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D2, Muscle Damage, NASCAR Pitcrew

NCT01825616
View directory record Official record
Conditions
Muscle Function, Muscle Soreness, Vitamin D Status
Interventions
Vitamin D2 mushroom powder, Placebo
Dietary Supplement · Other
Lead sponsor
Appalachian State University
Other
Eligibility
20 Years to 40 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cranberry Ingestion and Cycling Related Immunity and Inflammation

NCT05407701
View directory record Official record
Conditions
Inflammatory Response, Metabolic Disturbance, Immune Suppression
Interventions
Cranberry Juice, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Effects of Probiotic Supplementation on Markers of Muscle Damage and Performance Following Exercise Induced Muscle Damage

NCT02520583
View directory record Official record
Conditions
Probiotics
Interventions
Lactic acid bacteria and bifidobacteria, Placebo
Dietary Supplement · Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Almond Supplementation and Exercise Recovery

NCT04958018
View directory record Official record
Conditions
Muscular Injury
Interventions
Almonds, Snack bars
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
30 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage

NCT02231190
View directory record Official record
Conditions
Tendon Injuries
Interventions
GSK1278863, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 35 Years · Male only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Jun 7, 2026, 11:01 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

EIMD Mechanisms Causing Force Loss

NCT02125643
View directory record Official record
Conditions
Healthy
Interventions
Caffeine, Flour
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 35 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Jun 7, 2026, 11:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Two Eccentric Protocols on Muscle Damage

NCT06992271
View directory record Official record
Conditions
Eccentric Hypertrophy, Muscle Damage
Interventions
Fast Eccentric, Slow Eccentric
Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 35 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Jun 7, 2026, 11:01 AM EDT