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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:27 PM EDT

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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Exotropia Clear all
Completed Phase 3 Interventional Results available

Full-Time Occlusion Therapy for Intermittent Exotropia in Children

NCT05462821
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Eye Patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 8 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
25
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Berkeley, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Recruiting Not applicable Interventional

Improving Control of Intermittent Exotropia

NCT07272005
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
dichoptic videos, standard videos
Other
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
4 Years to 10 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Not listed Not applicable Interventional

Monitored Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia

NCT02902887
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Controlled Intermittent Alternate Occlusion (CIAO ) glasses
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 11 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional

Trial of Vision Therapy for Intermittent Exotropia

NCT04487249
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Vision Therapy
Other
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
8 Years to 16 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Birmingham, Alabama • Fullerton, California • Stanford, California + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Terminated Not applicable Interventional Results available

Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia

NCT02466659
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
CIAO therapy Amblyz glasses
Device
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 11 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2017 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia

NCT02223650
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Overminus treatment, Non-overminus treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 6 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Fullerton, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent Exotropia

NCT01032603
View directory record Official record
Conditions
Exotropia
Interventions
Bilateral lateral rectus recession (BLRc), Unilateral lateral rectus recession with medial rectus resection (R&R)
Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 10 Years
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Active, not recruiting Not applicable Interventional

Improving Control of Alignment in Intermittent Exotropia

NCT04199871
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
dichoptic 3D movies
Other
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
3 Years to 12 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional

Using Dichoptic Therapy to Treat Intermittent Exotropia

NCT06529016
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Luminopia, a virtual reality headset, Paper pre- survey, Paper Survey
Device · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years to 7 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Observation Versus Occlusion Therapy for Intermittent Exotropia

NCT01032330
View directory record Official record
Conditions
Exotropia
Interventions
occlusion treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
12 Months to 10 Years
Enrollment
611 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Fullerton, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 21, 2026, 6:27 PM EDT
Not listed Phase 2Phase 3 Interventional

Bupivacaine Injection of Eye Muscles to Treat Strabismus

NCT01616108
View directory record Official record
Conditions
Strabismus, Esotropia, Exotropia, Graves Disease, Ptosis, Eyelid
Interventions
Bupivacaine
Drug
Lead sponsor
Smith-Kettlewell Eye Research Institute
Other
Eligibility
8 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Oct 21, 2026, 6:27 PM EDT
Terminated Not applicable Interventional

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

NCT05242510
View directory record Official record
Conditions
Exotropia
Interventions
Patching, Prism Adaptation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
Up to 17 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 21, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Trial of Overminus Spectacle Therapy for Intermittent Exotropia

NCT02807350
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Overminus treatment, Non-overminus treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 10 Years
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
59
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 6:27 PM EDT
Recruiting No phase listed Observational

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

NCT04770519
View directory record Official record
Conditions
Strabismus, Nystagmus, Congenital
Interventions
whole genome sequencing or whole exome sequencing
Genetic
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 21, 2026, 6:27 PM EDT