Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:32 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
Interventions: ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique; Procedure
Lead sponsor: Marshall University; Other
Eligibility: 14 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Huntington, West Virginia

Conditions: Ankle Fractures, Tibia Fracture
Interventions: CBD, Placebo; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Hallux Limitus
Interventions: standard of care, Metarsal Dynasplint; Other · Device
Lead sponsor: Dynasplint Systems, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 3
States / cities: Boston, Massachusetts • Henderson, Nevada • Houston, Texas

Conditions: Hip Fractures, Hip Arthropathy, Surgery, Delirium
Interventions: Blood pressure management according to cerebral autoregulation, Blood pressure management according to usual care; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 60 Years to 100 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Ulcers, Wounds
Interventions: Traditional NPWT System, SNaP Wound Care System; Device
Lead sponsor: 3M; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 17
States / cities: Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 14 more

Conditions: Blood Flow Restriction, ACL Tear, ACL Injury
Interventions: Blood Flow Restriction using Delfi Personalized Tourniquet System; Device
Lead sponsor: Connecticut Children's Medical Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Acute Compartment Syndrome, Fracture, Bone, Tibial Fractures
Interventions: Tissue Ultrafiltration Catheters; Device
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 4
States / cities: Baltimore, Maryland • Minneapolis, Minnesota • Charlotte, North Carolina + 1 more

Conditions: Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Implant, Knee Injuries
Interventions: Klassic Knee System; Device
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder, Pain, Loss of Function
Interventions: Not listed
Lead sponsor: Loma Linda University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: San Bernardino, California

Conditions: Ankle Fractures
Interventions: Postoperative protocol (Immediate weight bearing), Postoperative Protocol (Delayed Weight Bearing); Other
Lead sponsor: Kyle Schweser MD; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Tibial Fractures, Lower Extremity Fracture
Interventions: Blood Flow Restriction with low load exercise, Therapeutic Exercise; Device · Other
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 18 Years to 100 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Tibial Plateau Fractures
Interventions: Blood Flow Restriction Cuff, Physical Therapy; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Femoral Fractures, Pain, Postoperative
Interventions: Marcaine; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 7 Years to 14 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 2
States / cities: St Louis, Missouri

Conditions: Anterior Cruciate Ligament Tear, Medial Collateral Ligament
Interventions: Leg Sleeve, Placebo; Device
Lead sponsor: Texas Bone and Joint; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Denton, Texas

Conditions: ACL Tear
Interventions: ACL reconstruction, Mesenchymal stem cell implantation; Procedure
Lead sponsor: Andrews Research & Education Foundation; Other
Eligibility: 14 Years to 50 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Gulf Breeze, Florida

Conditions: Proximal Tibia Fracture, Tibial Shaft Fracture, Acute Compartment Syndrome
Interventions: Continuous Compartmental Pressure Monitor; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 10 Years to 21 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Fractures, Bone, Fractures, Closed, Fractures, Open, Fracture of Femur, Fracture Nonunion, Fracture of Tibia, Limb Deformity, Limb Fracture, Limb Defect, Limb Asymmetry
Interventions: Fitbone Transport and Lengthening System; Device
Lead sponsor: Orthofix Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 9
States / cities: Los Angeles, California • Orange, California • Atlanta, Georgia + 6 more

Conditions: Hip Fracture
Interventions: Nutrition, PUSH, PULSE; Dietary Supplement · Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 60 Years and older
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 4
States / cities: Farmington, Connecticut • Baltimore, Maryland • Lebanon, New Hampshire + 1 more

Conditions: Tibial Meniscus Injuries, Tibial Meniscus Tears, Tibial Meniscus, Torn, Anterior Cruciate Ligament Tear
Interventions: Zilretta, Placebo; Drug · Other
Lead sponsor: Austin V Stone; Other
Eligibility: 18 Years to 40 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Bone Cement Implantation Syndrome
Interventions: Administration of general anaesthesia, Neuraxial Analgesia; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Spinal Cord Injuries
Interventions: Ekso Indego Therapy, Wandercraft Atalante X; Device
Lead sponsor: Georgia Institute of Technology; Other
Eligibility: 18 Years to 70 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Neurocognitive Component; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Of Bypass Graft of the Extremities, Peripheral Arterial Disease, Vascular Diseases, Cardiovascular Diseases
Interventions: PICO Single-Use Negative Pressure Dressings, Sterile Gauze Dressings; Device · Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 35 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tibial Fractures
Interventions: micromotion intramedullary nail cohort, standard intramedullary nail cohort; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Search by objective public record fields.

The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults

CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF

Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial

Optimizing Cerebral Autoregulation During Surgery

SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds

Blood Flow Restriction Training (BFR) in an Adolescent Population

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA)

Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery

Efficacy Study of Femoral Nerve Block in Children With a Femur Fracture

A Study to Evaluate the Incrediwear Products Immediately After ACL Repair

Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier

MY01 Pressure Monitoring in Adolescent Tibia Fractures

Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System

Improving Community Ambulation After Hip Fracture

Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury

Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS)

Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury

Adding Neurocognitive Component to Balance Test

Standard Versus PICO Dressings in Lower-Extremity Bypass Patients

Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing